Afloderm cream 0.05% 40gr

Afloderm instruction for use

You can buy Afloderm cream on this page

Composition

The drug contains dipolpionate as an active substance of alklomethasone.
Cream Afloderm also has the following additional components: propylene glycol, sodium dihydrogen phosphate dihydrate, cetostearyl alcohol, macrogol glyceryl stearate, sodium hydroxide, chlorocresol, phosphoric acid, macrogol cetostearate, soft white wax, purified water.
In turn, the ointment contains such auxiliary substances: paraffin soft white, propylene glycol monopalmitostearate, beeswax white, hexylene glycol.

Form of issue

Pharmacies sell cream and ointment Afloderm.

pharmachologic effect

The drug has anti-inflammatory, antipruritic, anti-allergic and antiproliferative properties.

Pharmacodynamics and pharmacokinetics

The drug acts as an anti-inflammatory, vasoconstrictive and itching-stopping agent. It is believed that its active substance induces the synthesis of phospholipase A2 inhibitors. As a result, the release of arachidonic acid from the phospholipids of the membranes is reduced. This causes oppression of the synthesis of prostaglandins and leukotrienes from arachidonic acid.
With local application of Afloderm to a healthy skin area, 3% of the active substance is absorbed into the circulatory system. If the skin is damaged or an occlusive dressing is used, the degree of absorption may be higher.
Splits the drug in the liver. Most of the metabolites are excreted in the urine, the rest - with bile.

Indications for use

The medicine is prescribed for:
    atopic dermatitis;
    psoriasis;
    solar dermatitis;
    eczema;
    allergic and contact dermatitis;
    allergic reaction to insect bites.
You can use this product for children from 6 months.

Contraindications

The drug is contraindicated for use when:
    hypersensitivity to its components;
    cutaneous manifestations of syphilis;
    viral skin infections;
    open wounds;
    trophic ulcers;
    skin tuberculosis;
    chicken pox;
    skin postvaccinal reactions;
    children up to six months.

Side effects

Cream and ointment rarely cause negative reactions. As side effects, rashes, erythema, irritation, itching, dry skin, acne are possible. In rare cases, changes in skin resembling acne, folliculitis, stretch marks, hypertrichosis, secondary skin infections, hyperpigmentation, atrophic skin changes, enlargement of superficial vessels, allergic contact dermatitis are reported. Negative reactions at the site of application are more often manifested when using an occlusive dressing.
Systemic side effects can lead to suppression of adrenal function. It is assumed that this is possible with prolonged use on large areas of skin.

Instructions for use Afloderm (Method and dosage)

Cream Afloderm instructions for use recommends use for the treatment of acute skin lesions, and ointment - for the purpose of treating subacute and chronic dermatoses.
After the acute period of the disease is over, and also if the drug is used on dense areas of the skin or it is necessary to remove the inflammatory effect in denser layers of skin, it is desirable to use Afloderm as an ointment.
The preparation in the form of a cream is well absorbed and does not leave a fat shine.
The medicine is applied with a thin layer evenly to the affected skin. Do this 2-3 times a day. If you need to apply a cream or ointment to areas where the skin is more dense, for example, elbows or feet, and also easily erased, you can apply the medicine more often.
Instructions for use Afloderm reports that for children, when the main symptoms begin to pass, the remedy can be used once a day.
In order to prevent relapse, treatment should be continued for some time after the skin returns to normal.
When used for young children, it should be taken into account that the skin folds and synthetic diapers can affect the same as the occlusive dressing. Thus, the degree of absorption of the active component is increased. In addition, in children absorption may be higher due to insufficient maturation of the skin.
It is not advisable to apply cream and ointment under occlusive dressings in areas where diapers and diapers touch the skin. Therapy for children lasts a maximum of 3 weeks. If you need to use the drug longer, you need to do this under the supervision of a specialist.
If the effect of the drug is not visible within two weeks, it is necessary to check the diagnosis.

Overdose

If the drug is applied to large areas with prolonged therapy, as well as with the use of occlusive dressing and in childhood, the active substance can be absorbed more. Then it can lead to glucosuria, hyperglycemia, oppression of the hypothalamic-pituitary-adrenal system with growth retardation, Cushing's syndrome and intracranial hypertension.
In rare cases, fever, arthralgia, myalgia, general weakness is possible.
When symptoms of an overdose appear, the medicine should be withdrawn. Treatment is symptomatic. Normal measures are used to maintain normal body functions.

Interaction

Significant interaction with other drugs has not been established.

Terms of sale

You can buy this medicine without a prescription.

Storage conditions

The optimum temperature is up to 30 ° C. Keep the medicine in a place inaccessible to small children.

Shelf life

For the ointment, the shelf life is 3 years, and for the cream - 2 years.

Reviews about Afloderm

Reviews about ointments and cream on the Internet can be found very different. For most people, the drug helps. Those who have tried the cream or ointment Afloderm note their rapid action and effectiveness. The beneficial effect of the remedy is already noticeable from the first days of use. Parents who used the medicine for children, reviews about Afloderm also leave positive.
However, there are those who did not get the drug. They say that the remedy turned out to be ineffective. As a rule, people who tried to remove inflammation on dense skin areas write about it. But the side effects are almost not reported. In general, the drug is well tolerated.