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Pimafucin user manual

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Composition

The composition of the candle includes natamycin, as an active ingredient. Among the additional components: cetyl alcohol, adipic acid, solid fat, trioleate sorbitan, polysorbate 80, sodium bicarbonate.
Ointment Pimafucin. The main component is natamycin. Auxiliary components: propylene glycol, cetostearic alcohol, sodium laurip sulfate, purified water, decylletate, methyl parahydroxybenzoate, cetyl ether, propyl parahydroxybenzoate.
Tablets Pimafucin. The active ingredient in the tablets is natamycin, auxiliary ingredients: kaolin, white beeswax, polyvinylpyrrolidone, titanium dioxide, sucrose, magnesium stearate, kaolin, methyl parahydroxybenzoate, gelatin, gum arabic, potato starch, calcium carbonate, lactose, triacetin.

Form of issue

The drug is available in three forms: tablets, cream and vaginal suppositories from thrush. White round tablets are available in 20-pound vials of dark glass. The cream has a white or light yellow color, made in aluminum or plastic tubes of 30 g. Suppositories are produced in foil strips, in which there are 3 candles, the package can be 1 or 2 strips.

pharmachologic effect

Pimafucin has an antifungal and fungicidal effect.

Pharmacodynamics and pharmacokinetics

The principle of the drug's effect is based on the binding of sterols in the cell membrane, the violation of their integrity, which causes the death of the microorganism. The drug acts on yeast-like fungi (especially Candida albicans), yeast, dermatophytes, pathogenic fungi.
Natamycin is active when used topically, has no systemic effect, is not absorbed through mucous membranes or skin. The intestinal-soluble coating of tablets determines the effect of the drug in the intestine.

Indications for use

Pimafucin cream is prescribed for fungal lesions of nail plates, skin and mucous membranes, including vulvovaginitis, balanoposthitis, vulvitis, vaginitis, dermatomycosis, otitis caused by fungi or complicated by candidiasis, candidiasis of nails, skin.
Pimafucin in tablets is effective in fungal diseases of the external auditory canal, mucous membranes, oral cavity. It is prescribed for candidiasis of the intestine, after therapy with corticosteroids, antibiotics, cytostatics, vulvovaginitis, vulvitis, vaginitis, acute atrophic or pseudomembranous candidiasis with cachexia.
Candles Pimafucin is prescribed for balanoposthitis, vulvovaginitis, vulvitis, vaginitis caused by Candida fungi.

Contraindications

With increased sensitivity to substances that are part of Pimafucin, the drug is contraindicated.

Side effects

Tablets at the beginning of therapy can cause nausea or diarrhea, during further treatment, these symptoms are eliminated spontaneously.
With topical application (suppository or cream), slight irritation of the skin or burning may occur.

Instructions for use Pimafucin (Method and dosage)

Suppositories Pimafucin, instructions for use. Used intravaginally. With vulvovaginitis, vulvitis and vaginitis is administered 1 candle 3-6 days. To enter it is necessary in a position "lying down", it is as deep as possible, before a dream once a day. If treatment of Candida albicans caused by vaginitis does not help, then take the pill - 10-20 days, 1 tablet four times a day. For men, the cream is used during treatment. Duration of treatment is established in each case individually. After the symptoms of the disease disappear, a few more days should be continued.
Instructions for the cream. It is applied externally. On the affected areas from one to several times a day, ointment should be applied with balanoposthitis, vulvovaginitis and vulvitis. If symptoms persist, suppositories or tablets are prescribed. With dermatomycosis (including diaper rash in children and candidiasis of nails and skin), the suspension should be applied to the nails and skin up to 4 times a day.
In case of mycosis of the external auditory meatus, the affected area should be lubricated with cream a day up to four times, after having cleansed the ear. After application, it is necessary to place in the ear canal a turunda of cotton or wool. Duration of treatment is determined individually. After the symptoms completely disappear, several days must not be stopped.
Instructions for the use of tablets. Adults with candidiasis intestine appoint 1 tablet four times a day, children - 1 tablet twice a day. The average course of treatment lasts a week.

Overdose

About cases of overdose at the moment is not known.

Interaction

Not described.

Terms of sale

To buy Pimafucin the prescription is not needed.

Storage conditions

At a temperature of about 25 ° C.
Shelf life - 24 months.

special instructions

Under the influence of body temperature, vaginal suppositories quickly dissolve, thus forming a foamy mass, so that the active substance is distributed evenly. With recurrent or chronic infection, therapy can be supplemented with a cream or tablets.
Cetyl alcohol, part of the suppository, can cause burning in the genital area. It is necessary to interrupt the therapy with candles during menstruation. During treatment with suppositories it is possible not to exclude sexual contacts. Nevertheless, it is necessary to examine both partners, and when a lesion is detected, use Pimafucin Cream for men. Treatment for ointment for men occurs in the manner prescribed by the instruction. During sexual intercourse, barrier contraceptives should be used during treatment.
Perhaps the appointment of Pimafucin to the newborn.

With alcohol

Alcohol in combination with Pimafucin can lead to consequences that are undesirable for the body. It is strictly forbidden to drink alcoholic beverages during intestinal candidiasis. Alcoholic drinks lead to an exacerbation of fungal diseases, which can cause prolongation of treatment or its inefficiency.

Pimafucin in pregnancy and lactation

There are no contraindications to taking the drug for pregnant women and breastfeeding. Used tablets, cream and candles from thrush both in the early stages of pregnancy, and at later stages. Most often, Pimafucin supplements are prescribed during pregnancy, and not other forms of this medication. The drug is non-toxic and safe for the fetus, both during the first trimester and the 2nd trimester, and during lactation. Nevertheless, to minimize the risk, it is better to take candles with lactation, or cream. Use of the drug - as indicated in the instructions.

Reviews of Pimafucin

In the forums, the vast majority of patients after the application of the medication note a positive effect. However, there are cases when there is no improvement in the condition or even worse. There are also complaints about the short-term effect of treatment for thrush and other diseases.
Pifamucin from thrush, according to patients, helps, quickly eliminating its symptoms. Moreover, the cream is effective for both women and men. Pimafucin tablets with thrush also help in the treatment and prevention of candidiasis.
Reviews of tablets are usually good, patients write about the rapid and effective action of the drug and the complete absence of side effects. Reviews for candles Pimafucin with thrush report that they quickly relieve itching than when taking tablets, since they act locally. Negative reviews of the cream of Pimafucin not, it is good for fungal diseases and is easily tolerated. Most often, ointment is prescribed to men. Positive reviews during pregnancy indicate that the drug does not affect the development of the fetus and is very well tolerated, quickly eliminating the disease.