Ledibon tabs 2.5mg #28x3

Ledibon instruction for use

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Composition

Tibolone, micronized lactose monohydrate, potato starch, direct compression lactose, ascorbyl palmitate, magnesium stearate.

Release form

White round tablets, flat in a blister strip package in a cardboard crustacean No. 28, 84.

pharmachologic effect

Estrogen-progestin.

Pharmacodynamics

The drug belongs to the group of anabolic steroids. It has estrogen-progestin and mild androgenic effect. After the extinction of ovarian function normalizes the hypothalamic-pituitary system, reduces the production of gonadotropic hormones. In the postmenopausal period, it slows down the process of bone resorption, alleviates or stops the symptoms of menopausal syndrome (headaches, flushing to the face, increased sweating).
It has a positive effect on mood and libido, stimulates the vaginal mucosa, without causing proliferation of the endometrium. Suppresses ovulation in women of fertile age. Reduces the concentration in the serum of phosphate ions and calcium, prevents osteoporosis.

Pharmacokinetics

The drug is rapidly absorbed from the gastrointestinal tract. Food consumption on absorbability effects. The concentration of Tibolon in the blood is low due to the rapid metabolism process, cumulation is absent. Metabolized to pharmacologically active metabolites. Excreted from the body with feces and slightly with urine in the form of sulfated metabolites.

Indications for use

Postmenopausal estrogen deficiency. Prevention of osteoporosis and bone fractures in the postmenopausal period with contraindications for taking other drugs prescribed for the prevention of osteoporosis.

Contraindications for Ledibon

High sensitivity to the drug, the presence or suspicion of hormone-dependent tumors, pronounced abnormal liver function, cerebrovascular disorders, a history of endometrial hyperplasia, thromboembolism, thrombophlebitis, vaginal bleeding of unknown etiology, the period of up to one year after the date of the last menstruation, the period of pregnancy, a pregnancy, a pregnancy, a pregnancy, a pregnancy, a pregnancy.
Take the drug with caution in migraine, endometriosis, hypercholesterolemia, endometrial hyperplasia, leiomyoma, renal failure, bronchial asthma, epilepsy, carbohydrate metabolism, systemic lupus erythematosus.

Side effects

Dizziness, depression, migraine, diarrhea, change in body weight, edema, seborrheic dermatitis, hypertrichosis, metrorrhagia, hemorrhagic rash, pruritus, endometrial proliferation, pain in the back, limbs, vaginal bleeding, lower limb thrombosis, arthralgia.

Ledibon, instructions for use (method and dosage)

Before starting therapy, it is necessary to exclude malignant tumors of the reproductive organs, especially in the presence of bleeding.
Rules for taking Ledibon: starting to take pills should be from the top row of the package, the pill that is marked on the corresponding day of the week, and then, in accordance with the day of the week before the end of the package.
The drug is taken daily, preferably at one time at a dosage of 1 tablet per day. Swallow the tablet whole, if necessary, zapit water. Dose adjustment for elderly patients is not required. The drug should be taken no earlier than one year after the date of the last natural menstruation. Failure to comply with this condition increases the risk of irregular bloody vaginal bleeding or discharge. After surgical menopause, drug treatment should begin immediately. Treatment of post-menopausal symptoms is desirable to begin with the lowest effective dose. The minimum course of admission Ledibon - 3 months.
The transition to tibolone from the cyclical mode of use of the drug's hormone therapy - taking Ledibon should be started immediately after the end of the previous treatment regimen (the next day), and when switching from a continuous treatment regimen with combined HRT drugs, you can start the Ledibon treatment any day.
In the case when the pill is missed, if the time interval does not exceed 12 hours, the missed dose of the drug should be taken as soon as possible. If the time interval exceeds 12 hours, you should skip this procedure, and take the next dose at the usual time. At the same time, with frequent misses of taking the drug increases the risk of vaginal bleeding.
Ledibon is not a contraceptive.

Overdose

When taking the drug in a dose that is many times higher than the therapeutic dose, nausea, vomiting, and vaginal bleeding may appear.

Interaction

The drug enhances the action of anticoagulants, because it enhances the fibrinolytic properties of blood.

Terms of sale

You can buy Ledibon without a prescription.

Storage conditions

At temperatures up to 25 ° C.
Shelf life - 2 years.

Ledibon Reviews

Responses of women and doctors about Ledibon are mostly positive:
“... I have been taking LadyBon tablets for almost three years. Currently a quarter pill per day. This dose is enough for me. No problem, feeling good. Very pleased.