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Verospilactone caps 50mg #30

  • $9.54
  • 3 or more $9.35
  • Availability:In Stock

User manual for VerospilactoneReed more and buy Verospilactone hereCompositionTablets - spironolactone, magnesium stearate, milk sugar, potato starch, colloidal silicon dioxide, talc.Capsules - spironolactone, 2% titanium dioxide,..

Tags: caps

User manual for Verospilactone

Reed more and buy Verospilactone here


Tablets - spironolactone, magnesium stearate, milk sugar, potato starch, colloidal silicon dioxide, talc.
Capsules - spironolactone, 2% titanium dioxide, gelatin.

Form of issue

    Tablets 25 mg of white color of round shape, flat-cylindrical, odorless, in a blister pack, in cardboard pack No. 20 and 40.
    Capsules gelatinous 25,50,100 mg, in blister packing, in cardboard pack № 10, 30, 50.

pharmachologic effect

Diuretic, hypotensive.

Pharmacodynamics and pharmacokinetics


The drug is an antagonist of aldosterone and belongs to the group of potassium-sparing diuretics. Spironolactone in nephrons inhibits sodium water retention by aldosterone and suppresses the potassium-releasing effect of aldosterone.
The drug binds to aldosterone receptors, enhances the process of releasing chlorine, sodium and water ions in the urine, reduces the excretion of urea and potassium ions and the acidity of urine. The therapeutic effect comes in 7 hours and lasts no less than 24 hours. The hypotensive effect is due to a diuretic effect.


The drug is rapidly absorbed from the digestive tract and transformed into active metabolites. The connection with blood proteins is high (about 98%). Stam in the blood is reached after 3 hours. Spironolactone weakly penetrates tissues and organs, and its metabolites penetrate the BBB and into breast milk. The half-life of Spironolactone is 12-20 hours, its metabolites - up to 16 hours. It is excreted as metabolites (50%) and unchanged (10%) with urine and partly with feces.

Indications for use

    edema of various genesis (with cirrhosis of the liver, CHF, nephrotic syndrome, swelling during pregnancy in the II and III trimesters);
    arterial hypertension;
    premenstrual syndrome and polycystic ovaries, hirsutism;
    primary hyperaldosteronism;
    hypokalemia in the treatment of saluretic and its prevention;
    aldosterone producing adrenal adrenal gland.


Hypersensitivity to the drug, Addison's disease, chronic renal failure, anuria, hyperkalemia, diabetes mellitus, hyponatremia, hypercalcemia, breast tenderness, I trimester of pregnancy, metabolic acidosis, hepatic insufficiency, menstrual cycle disorder. Take with caution at the age of 60 years, with cirrhosis.

Side effects

Dizziness, headache, drowsiness, retardation, nausea, abdominal pain, vomiting, gastritis, bleeding in the gastrointestinal tract, diarrhea, intestinal colic, increased urea levels, decreased potency, hypercreatininaemia, alkalosis or acidosis, thrombocytopenia, agranulocytosis.
When receiving spironolactone for a long time - a violation of erection, dysmenorrhea, amenorrhea, gynecomastia, hirsutism, tenderness and enlargement of the mammary glands, coarsening of the voice, local allergic reactions, breast cancer.

Verospilactone, instructions for use (Method and dosage)

Capsules / Tablets taken after meals. The daily dose can be taken for one or more doses. The dosage of the drug (initial and maintenance) is selected individually depending on the disease, drug tolerance and age of the patient.
Edema on the background of CHF: the initial dose of 25 mg / day, the maximum - 100 mg.
Edema in cirrhosis: the dose is selected depending on the ratio of sodium and potassium and varies within the range of 100-400 mg / day.
Edema in nephrotic syndrome: daily dose of 100-200 mg.
With essential hypertension: a daily dosage of 50-100 mg. If necessary, the dose can be gradually increased to 200 mg. Duration of taking the drug for at least two weeks.
Children daily appoint at the rate of 3 mg / kg of weight and divide it into 1-2 admission.


It is manifested by drowsiness, nausea, vomiting, confusion, diarrhea, skin rash. Less common is dehydration and electrolyte imbalance.


Spironolactone with simultaneous administration with anticoagulants reduces their effectiveness. The drug increases the effect of antihypertensive drugs and diuretics. With simultaneous reception of Spironolactone with drugs containing potassium and potassium supplements, ACE inhibitors, potassium-sparing diuretics, the risk of hyperkalemia increases.
Against the background of taking the drug reduces the toxicity of cardiac glycosides. Spironolactone lowers the sensitivity of blood vessels to norepinephrine. The intake of diuretics and GCS accelerates and intensifies the natriuretic and diuretic action of Spironolactone.
Indomethacin, salicylates - diuretic effect of spironolactone are reduced.
With the simultaneous administration of Veroshpiron and lithium preparations, the toxic effect of the latter increases.

Terms of sale

To buy Verospilactone you don't need a prescription.

Storage conditions

At temperatures up to 30 ° C.
Shelf life - 2 years.

Reviews about Verospilactone

Reviews about the drug are mostly positive. Patients note its high efficiency.
    "... application of Verospilactone well removes swelling with my bouquet of sores: hypertensive disease of chronic heart failure."
Some note the development of side effects, in particular, from the gastrointestinal tract. Sometimes on the forums ask the question: Veroshpiron and Verospilactone have significant differences or not? There are no significant differences between them, except for dosage and manufacturers.

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