Verospiron caps 50mg #30

Verospiron user manual

Reed more and buy Verospiron online

Composition

INN: spironolactone. Contains 25 mg for tablets, 50 or 100 mg for capsules.
Additional substances in tablets: talc, silicon dioxide, lactose monohydrate, magnesium stearate, corn starch.
Additional substances in capsules: sodium lauryl sulfate, lactose monohydrate, magnesium stearate, corn starch.
In the lid and body of the capsule, gelatin, dyes and titanium dioxide are also contained.

Form of issue

The drug is available in the form of capsules and tablets.

pharmachologic effect

Competitive antagonist of aldosterone, a potassium-sparing diuretic.

Pharmacodynamics and pharmacokinetics

The main substance is spironolokton. In the distal sections of the nephron prevents water retention and sodium aldosterone, reduces the potassium-releasing effect of aldosterone, reduces the synthesis of permeases. The maximum effect of taking the drug is noted 7 hours after taking the capsule, last for 24 hours. Reduction of blood pressure is achieved diuretic effect, it manifests itself after 2-5 weeks of admission. The active substance becomes an active metabolite. The medicine is excreted by the kidneys.

Indications for use Verospiron

What is the medicine for? Consider for what purpose Verospiron.
Tablets and capsules are used in combination therapy with essential hypertension. Indications for the use of Verospiron are also: edematous syndrome with CHF, nephrotic syndrome, ascites, liver cirrhosis. The drug is also used as an auxiliary substance in the prevention of hypomagnesemia / hypokalemia in the treatment of diuretics. The drug is successfully used in the syndrome of Kona during the preoperative short-term course of treatment, and also with the purpose of establishing the diagnosis of "Primary hyperaldosteronism".

Contraindications

Contraindications to Verospiron are: hypersensitivity to the components of the drug, hyperkalemia, hyponatremia, Addison's disease, anuria, severe renal failure (CC less than 10 ml / min), pregnancy and lactation. With special care, the drug is prescribed for metabolic acidosis, hypercalcemia, AV blockade, diabetes mellitus, diabetic nephropathy, menstrual irregularities, general and local anesthesia, liver, kidney, and elderly patients.

Side effects

Gastrointestinal tract: diarrhea, nausea, vomiting, gastritis, constipation, intestinal colic, impaired liver function.
Central nervous system: retardation, ataxia, headaches, dizziness, lethargy, drowsiness, muscle spasm, confusion, spasms of the calf muscles.
Side effects from the hemopoiesis: thrombocytopenia, agranulocytosis, megaloblastosis.
Metabolism: hypercreatininaemia, hyperuricemia, hyperkalemia, increased urea levels, hyponatremia, hyperchloremic metabolic alkalosis and acidosis.
Endocrine system: men can develop gynecomastia, erectile dysfunction, decreased potency. In women, amenorrhea, dimenorrhea, hirsutism, terorrhagia, and breast carcinoma are possible.
Allergic reaction: itching, drug fever, hives, erythematous, maculopapular rash.
Dermatological reaction: hypertrichosis, alopecia.
Urinary system: acute renal failure.

Instructions for use Verospiron (Method and dosage)

On the capsules and tablets Verospiron instructions for use coincides. Everything depends on the amount of active substance taken.
Essential hypertension: Adults: 50-100 mg once. The dose can be gradually increased to 200 mg, the amount of the drug is increased 1 time in 2 weeks.
Idiopathic hyperaldosteronism: 100-400 mg per day.
Pronounced hyperaldosteronism, hypokalemia: per day 300 mg for 2-3 doses. Gradually, the dose of the drug is reduced to 25 mg per day.
Hypomagnesemia, nipokaliemia, provoked by the action of diuretics: 25-100 mg per day, once or for several doses.
Diagnosis and treatment of primary hyperaldosteronism: 400 mg per day for 4 days. The daily dose of the drug is divided into several receptions.

How to take with edema?

Edema in nephrotic syndrome: adults 100-200 mg per day. Verospiron is used only if other methods of treatment have proved ineffective.
Edema in CHF: 100-200 mg per day (several doses) for 5 days in combination with thiazide and loop diuretics. The daily dose can be reduced to 25 mg.
Edema in cirrhosis: with a ratio of Na + / K + in the urine above 1.0, then designate 100 mg. If less than 1.0, the daily dose is 200-400 mg.
Edema in children: initially 1-3.3 mg per 1 kg of body weight, or 30-90 mg / m2 per day for 1-4 doses. After 5 days, dose adjustment is performed.

How long can I take?

The usual course is 20 days, followed by a break of at least six months. The longest can be used for a couple of months. With long use, you can get acute kidney failure.

How to take before meals or after?

It is recommended to take the medicine after eating.

Overdose

Symptoms: diarrhea, dizziness, nausea, vomiting, skin rashes. Treatment is aimed at washing the stomach, increasing blood pressure.

Interaction

The drug reduces the effectiveness of mitotane, anticoagulants, increases the effect of antihypertensive and diuretic drugs. Stimulates the effect of Buserelin, Tryptrelelin, gonadorelin. With simultaneous admission with potassium preparations, the risk of hyperkalemia increases. Reduces the toxicity of cardiac glycosides. Indomethacin, salicylates lower the diuretic effect of the drug. Verospiron increases the metabolism of Antipyrin, increases the half-life of digoxin.

Terms of sale

You don't need a prescription to buy Verospiron.

Storage conditions

In a place inaccessible to children at temperatures up to 30 degrees Celsius.
Shelf life not more than 5 years.

special instructions

Verospiron in gynecology is prescribed to reduce the androgen rate in women with PCOS (polycystic ovary syndrome). The drug can cause bleeding, disrupt the menstrual cycle. Verospiron is often recommended together with contraceptives to normalize the menstrual cycle, reduce hirsutism.
In Wikipedia, there is no article about the preparation.

In pregnancy

The drug is contraindicated in pregnancy and breastfeeding.

Reviews about Verospiron

Reviews about Verospiron on the forums testify in favor of this drug. The medicine is effective, but it is advised to use it on the measure and on the prescription of the doctor, since the drug has side effects and contraindications.
Diuretic tablets fully cope with the function assigned to them, and also effectively help with edema. In gynecology, the drug is successfully used in the process of writing.
Helps Verospiron and slimming, as it has a diuretic property.
Those who use the medicine say that it does not help with hirsutism.