Magnistad tabs #50

Magnistad instruction for use

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Indications for use

Magnistad is used to treat an established deficiency of magnesium, isolated or associated with other deficient conditions, accompanied by symptoms such as:
- increased irritability;
- minor sleep disorders;
- gastrointestinal spasms;
- cardiopalmus;
- increased fatigue;
- pain and muscle spasms;
- tingling sensation.

Contraindications

- hypersensitivity to the components of the drug;
- marked renal failure (creatinine clearance less than 30 ml / min);
- phenylketonuria;
- children's age till 6 years;
- deficiency of lactase;
lactose intolerance;
- Glucose-galactose malabsorption (the preparation contains lactose).
It is necessary to prescribe with caution the drug with moderate failure of kidney function, since there is a risk of hypermagnesemia.
Magnistad can be used during pregnancy only on the recommendation of a doctor.
Avoid the use of the drug during lactation. If the drug is still needed, breastfeeding should be discontinued.

Dosing and Administration (Instruction)

Magnistad is taken orally, with food, with a glass of water.
Adults are recommended to take 6-8 tablets per day.
Children older than 6 years (body weight over 20 kg) are recommended to take 4-6 tablets per day.
The daily dose should be divided into 2 - 3 doses. The average course of treatment is 1 month.
Immediately after the normalization of the magnesium level in the blood, the drug should be stopped.

Pharmachologic effect of Magnistad

Magnistad is a combined preparation containing therapeutic doses of magnesium lactate and pyridoxine hydrochloride (the latter improves the absorption of magnesium in the intestine, its transport from the blood and intercellular fluid into the cells).
Magnesium ensures the supply of glycolysis products to the Krebs cycle, is involved in the synthesis and decomposition of nucleic acids, the synthesis of proteins, fatty acids and lipids, in particular phospholipids, also participates in the synthesis of enzymes that provide energy reactions. Magnesium is necessary for the implementation of neuromuscular transmission, the mineralization of bones, the realization of the effect of parathyroid hormone, for the normal exchange of neurotransmitters. Magnesium helps reduce insulin resistance of tissues and induce insulin-dependent glucose uptake.
Pyridoxine hydrochloride (vitamin B6) as coenzyme is involved in metabolic processes, is necessary for the normal functioning of the central and peripheral nervous system.

Side effects

Allergic reactions, abdominal pain, diarrhea, nausea, vomiting, flatulence.
With normal kidney function, oral magnesium intake does not cause toxic reactions. However, an overdose of magnesium can develop with renal failure.
Symptoms of an overdose of Magnostad: asystole, bradycardia, central nervous system inhibition, coma, hypotension (syncope), muscle paralysis, polyuria or oliguria, diplopia and blurred vision, shortness of breath.
Treatment of overdose: the drug should be discontinued; specific treatment - if the magnesium level in the blood is 10 mmol / l, 10 ml of a 10% calcium gluconate solution should be administered, but not more than 2 times.
Nonspecific - rehydration measures, forced diuresis.
With renal failure, hemodialysis or peritoneal dialysis is necessary.

Special instructions for Magnistad

Magnistad should not be taken on an empty stomach because of the possibility of developing diarrhea.
When combined with tetracyclines, it is necessary to observe an interval of 3 hours between the methods of Magnystad and the preparation of the tetracycline series. When combined with preparations containing phosphates or calcium salts, the interval of 1 hour should be observed.
The drug does not affect the ability to drive vehicles and control mechanisms.

Interaction

The simultaneous use of drugs containing phosphates or calcium salts can significantly reduce the absorption of magnesium in the gastrointestinal tract.
Magnesium preparations reduce the absorption of tetracycline.
Magnesium weakens the effect of oral thrombolytic agents, reduces the absorption of iron.
Pyridoxine decreases the effectiveness of levodopa.

Terms of sell

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