Artrosan tabs 15mg #20

User manual for Artrosan

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Composition

Artrosan tablets contain the active ingredient meloxicam 7.5 mg + excipients (colloidal silicon dioxide, lactose monohydrate, sodium citrate, potato starch, povidone, magnesium stearate).
In the 1 ml solution for intramuscular injection, 6 mg meloxicam and additional substances (glycine, sodium chloride, water, poloxamer, glycofurol, unimolar sodium hydroxide solution) are found.

Form of issue

The preparation is produced as:
    tablets of various shades of yellow, with chamfers, risk, flat form, in packages of 10, 15, 20, 30, 40, 45, 50, 60, 75 and 100 pieces;
    solution for intramuscular injection, clear, yellow-green, 5 ml ampoules of 3.5 and 10 pieces per package.

pharmachologic effect

Anesthetic, anti-inflammatory, antipyretic.

Pharmacodynamics and pharmacokinetics

The active ingredient meloxicam is a derivative of oxycam. It has an anti-inflammatory effect by blocking the synthesis of prostaglandins and the enzyme cicoxygenase-2, which takes part in a cycle of arachidonic acid.
Under the influence of meloxicam, the activity of the mediators of the inflammatory process and the permeability of the vascular walls is significantly reduced, the reactions with free radicals are inhibited. Anesthesia occurs due to a decrease in the activity of interaction of prostaglandins and nerve endings.
A stable maximum concentration is achieved within three to five days. It binds well to proteins in the blood plasma (99% and above). Metabolized in the liver, forming 4 metabolites. They do not play a role in the pharmacodynamic processes. Metabolites are excreted with feces and urine, for a period of 15 to 20 hours.

Indications for use

The medicine is prescribed for various inflammations of the joints, which are accompanied by a pain syndrome:
    osteoarthrosis;
    osteochondrosis;
    myositis;
    rheumatoid arthritis;
    radiculitis;
    ankylosing spondylitis.

Contraindications

    drug allergy or special sensitivity to the components of the drug, including the NSAID group;
    stomach ulcer and 12-colon;
    bronchial asthma;
    polyps in the nose and nasal cavity;
    bleeding and (or) hemorrhage in the stomach, intestines, etc .;
    severe forms of cardiac, renal and hepatic insufficiency;
    age up to 15 years;
    hemophilia;
    hyperkalemia;
    pregnancy and lactation.

Side effects

Possible occurrence:
    indigestion of the stomach, belching, gastric bleeding and stomach ulcers;
    hepatitis, an increase in the level and activity of liver enzymes, acute renal failure;
    bronchospasm, angioedema, peripheral edema;
    leukopenia, thrombocytopenia, anemia;
    tachycardia, anaphylaxis;
    esophagitis, allergic reactions on the skin, photosensitivity and skin itching;
    headache, drowsiness, dizziness, disorientation and blurred vision;
    stomatitis, conjunctivitis and urticaria.

Instructions for use Artrosan (Method and dosage)

Tablets are taken once a day, along with food, washed down with water. The recommended daily dose is from 7.5 mg to 15 mg, depending on the intensity of the pain syndrome and the course of the disease.
If the drug can not be taken orally, intramuscular injections may be prescribed.

Pricks Artrosan, instructions for use

Artrosan injections are prescribed for acute pain, during the first few days of illness. The injections of the medicine are made intramuscularly, deep into the tissue. The daily dose is from 7.5 to 15 mg, with therapy starting with small doses and increasing to achieve the desired effect.
Do not exceed the recommended dosage, possibly increasing the risk of side effects.

Overdose

Symptoms of overdose are
    indigestion;
    pain in the epigastric region, possible bleeding in the stomach;
    impaired consciousness;
    vomiting and nausea;
    asystole;
    stopping breathing;
    disorders in the work of the kidneys and liver.
Therapy - gastric lavage, enterosorbents, symptomatic.

Interaction

When combined:
    with pressure-lowering drugs, their effectiveness decreases;
    with diuretics and cyclosporine, the risk of renal failure is significantly increased;
    with antagonists of vitamin K, fibrinolytics, heparin, serotonin reuptake inhibitors - bleeding may occur.
With caution combine with intrauterine contraceptives, lithium preparations, colestyramine, other NSAIDs, methotrexate.

Storage conditions

Do not allow the drug to interact with water, direct sunlight, storage at temperatures above 25 degrees. Keep out of the reach of children.
Shelf life - 2 years.

special instructions for Artrosan

The use of the drug can mask the infectious diseases that occur in the body.
If you use the product for more than 14 days, you should monitor the liver and kidney function.
If the patient has a predisposition to the occurrence of a stomach ulcer and duodenal ulcer, use Artrosan is very careful.
When there are effects associated with a decrease in the speed of psychomotor reactions, work with mechanisms and driving vehicles should be stopped for a while.

Reviews about Artrosan

Reviews about pricks Artrosan good. The drug is relatively inexpensive and quite effective. Many helped to cope with the pain syndrome with various joint diseases. Taking pills, has the same effect as injections. Of the minuses, there are side effects in the form of headaches, stomach pains and dizziness, but it does not happen often.