Chondroxid tablets 250mg #60

Chondroxid tablets instruction for use

You can buy Chondroxid tablets on this page

Release form, composition and packaging

Tablets from white with a yellowish tinge to white with a creamy tint, blotches are allowed, with a dye and a bevel.
1 tab.
chondroitin sodium sulfate 250 mg
Excipients: calcium stearate monohydrate (calcium stearate 1-water) - 4.8 mg, crospovidone (polyplasdone XL-10, collidon CL-M) - 12.39 mg, povidone K30 (collidon 30) - 9.312 mg, microcrystalline cellulose - 96 mg, magnesium hydroxycarbonate pentahydrate (basic magnesium carbonate water) - 107.498 mg.

pharmachologic effect

A drug that regulates the metabolism of cartilage tissue. It has chondrostimulating, regenerating and anti-inflammatory effects.
Chondroxide is involved in the construction of the main substance of cartilage and bone tissue. Affects metabolic processes in hyaline and fibrous cartilage. It inhibits degenerative processes in cartilage and connective tissue, inhibits enzymes that cause damage to cartilage tissue.
Chondroxide stimulates the biosynthesis of proteoglycans, promotes the regeneration of the articular sacs and the cartilaginous surfaces of the joints, increases the production of the intra-articular fluid, and has an anti-inflammatory effect. It slows down bone resorption and reduces calcium loss, accelerates bone repair processes.
Hondroksid slows the progression of osteoarthritis and osteochondrosis. The use of Chondroxide tablets reduces pain and improves the mobility of the affected joints, while the therapeutic effect lasts a long time after the end of the course of therapy.

Pharmacokinetics

With a single ingestion of the average therapeutic dose of Tmax in the plasma is 3-4 hours, Tmax in the synovial fluid is 4-5 hours. Bioavailability is 13%.
It accumulates mainly in the cartilage tissue (Tmax in the articular cartilage is 48 hours): the synovial membrane is not an obstacle to the penetration of Chondroxide tablets into the joint cavity. Excreted by the kidneys within 24 hours

Indications

Degenerative-dystrophic diseases of the joints and spine:
- treatment and prevention of osteoarthritis, spinal osteochondrosis.

Contraindications

- pregnancy;
- lactation period;
- hypersensitivity to Chondroxid tablets.
Precautions should be used when bleeding or bleeding tendency.

Dosage

Chondroxid tablets should be taken orally at 500 mg (2 tab.) 2 times / day, with a small amount of water.
The recommended duration of the initial course of treatment is 6 months.
The therapeutic effect of Chondroxid tablets lasts for 3-5 months after its cancellation, depending on the location and stage of the disease. If necessary, it is possible to conduct repeated courses of treatment, the duration of which is determined individually.

Side effects

In some cases: allergic reactions, nausea, diarrhea.

Overdose

Symptoms: rarely - nausea, vomiting, diarrhea, with prolonged use in excessively high doses (more than 3 g / day) hemorrhagic rashes are possible.
Treatment: symptomatic treatment.

Drug interaction

Perhaps increasing the effect of indirect anticoagulants, antiplatelet agents, fibrinolitikov.

special instructions

When combined with indirect anticoagulants, antiplatelet agents, fibrinolitikami requires more frequent monitoring of blood coagulation.

Use in pediatrics

The efficacy and safety of chondroitin sulfate in children have not been established.

Influence on ability to drive motor transport and control mechanisms

Does not affect the ability to drive motor vehicles and other mechanisms.

Pregnancy and lactation

Chondroxid tablets are contraindicated during pregnancy and lactation.

Use in childhood

The efficacy and safety of chondroitin sulfate in children have not been established.

Pharmacy sales terms

You can buy Chondroxide tablets without a prescription.

Terms and conditions of storage

Chondroxid tablets should be stored out of the reach of children, dry, protected from light, at a temperature not exceeding 25 ° C. Shelf life - 2 years.