Troximetacin gel 40gr

Troximetacin instruction for use

You can buy Troximetacin gel on this page

Composition

1 g of the drug contains:
active ingredients: indomethacin 30 mg, troxerutin 20 mg;
excipients: carbomer 15 mg, disodium edetate 0.5 mg, sodium benzoate 2.5 mg, macrogol-400 522 mg, isopropanol 150 mg, dimethyl sulfoxide 150 mg, purified water 110 mg.

Description

Uniform, transparent gel from yellow to yellow-brown color.
Pharmacotherapeutic group: anti-inflammatory agent for topical use
ATH:
M.01.A.B.51 Indomethacin in combination with other drugs

Pharmacodynamics

The combined preparation for topical administration, which consists of indomethacin and troxerutin.
Indomethacin has a pronounced anti-inflammatory, analgesic and anti-edema effect, leading to pain relief, reduction of edema and shortening the recovery time of affected tissues. The main mechanism of action is associated with the suppression of the synthesis of prostaglandins by reversible blockade of cyclooxygenase 1 and 2.
Troxerutin (trihydroxyethyl rutinoside) is a bioflavonoid. It has an angioprotective effect. Reduces capillary permeability and shows venotonic action. Blocks the venodilating action of histamine, bradykinin and acetylcholine. It acts anti-inflammatory on the near-venous tissue, reduces capillary fragility and has some antiplatelet effect. Reduces swelling, improves trophism in various pathological changes associated with venous insufficiency.
Troximetacin gel, when applied to the skin, suppresses the inflammatory edematous reaction, reduces pain and temperature in the foci of inflammation located on the surface and in depth, reaching the blood vessels located there. It has a pronounced venotonic, capillary-protective effect.

Pharmacokinetics

The gel base used provides the solubility and release of Troximetacin components Indomethacin and Troxerutin.
Gel dosage form, which includes indomethacin and troxerutin, is well absorbed from the skin surface and provides a therapeutic effect of Troximetacin.
When applied to the skin in the subcutaneous tissue and periarticular tissues are concentrations close to therapeutic. The penetration of active ingredients into the systemic circulation is clinically insignificant.

Indications for Troximetacin gel

For symptomatic treatment:
- in the treatment of chronic venous insufficiency of the lower extremities (varicose veins) - to relieve swelling, feelings of heaviness and pain in the legs;
- superficial thrombophlebitis, phlebitis; post-phlebitis states;
- rheumatic lesions of soft tissues: tendovaginitis, bursitis, fibrositis, periarthritis;
- postoperative edema, contusions, dislocations, sprains.

Contraindications

- Hypersensitivity to Troximetacin;
- hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs);
- III trimester of pregnancy and breastfeeding period;
- children's age up to 14 years (due to the lack of clinical experience of use);
- violation of the integrity of the skin.

Carefully

Simultaneous use of Troximetacin with other NSAIDs, bronchial asthma, allergic rhinitis, nasal mucous polyps.
Pregnancy and lactation: Clinical experience that proves the safety of Troximetacin when used during pregnancy and during lactation is absent. The use of the drug is possible only if the expected benefit to the mother outweighs the potential risk to the fetus or child.

Dosage and administration

The gel is applied externally.
3-4 times a day by rubbing the gel with a thin layer into the skin of painful areas of the body. The amount required for a single rubbing is about 4-5 cm of gel squeezed out of a tuba. The total daily amount should not exceed 20 cm of gel. The duration of treatment should not exceed 10 days.

Side effects

Tolerability of Troximetacin is usually very good.

Local reactions

You may experience symptoms of hypersensitivity on the part of the skin - contact dermatitis, itching, redness, rash, a feeling of warmth and burning at the place of use.

Overdose

There is no information about cases of overdose with local use.
If you swallow large amounts of Troximetacin, you may have a burning sensation in the mouth, salivation, nausea, and vomiting.
Treatment: washing the mouth and stomach, if necessary - symptomatic treatment.

Interaction

The gel can enhance the effect of drugs that cause photosensitivity.
Clinically significant interactions with other drugs are not described.

Special instructions for Troximetacin gel

The drug should be applied only to intact skin, avoid contact with eyes and mucous membranes.
After applying the drug should not apply an occlusive dressing.
In case of contact with eyes, mucous membranes or open wound surfaces, local irritation is observed - tearing, redness, burning, pain.
The necessary measures in this case - washing the affected area with copious amounts of distilled water or saline solution to the disappearance or reduction of complaints.
Sodium benzoate and dimethyl sulfoxide, which are contained in the preparation as auxiliary substances, can irritate the skin.
Troximetacin does not affect the ability to perform potentially hazardous activities that require high concentration of attention and speed of psychomotor reactions (including driving and working with moving mechanisms).

Form release / dosage

Gel for external use.
Packaging:
40 g in aluminum tubes, with an internal lacquer coating, lithographed outer surface, membrane and sealing ring, with a plastic screw cap.
Each tube together with instructions for use are placed in a cardboard box.

Storage conditions

At a temperature not higher than 25 ° С.
Keep out of the reach of children.
Shelf life - 2 years.
Do not apply after the expiration date

Pharmacy Sale Terms

You can buy Troximetacin without a prescription.