Dorzopt Plus drops 20mg/ml + 5mg/ml 5ml

Dorzopt Plus instruction for use

You can buy Dorzopt Plus on this page

See also - Dorzopt

Form of formulation and composition of the preparation

The drug Dorzopt Plus is available in the form of eye drops in polymer bottles with a dropper on the tip of 5 ml. The vial is placed in a cardboard box with the detailed attached instruction. Drops are a sterile liquid, clear, odorless, color and foreign impurities. The main active components of Dorzopt plus are dorzalamid hydrochloride (20 mg in 1 ml) and timolol maleate 5 mg in 1 ml. As auxiliary components are: citric acid monohydrate, sodium hydroxide solution, purified water, benzalkonium chloride.

Pharmacological properties of the drug

Drops Dorzopt plus are a drug for the treatment of increased intraocular pressure. The drug includes 2 active ingredients - timolol and dorzolamide, whose therapeutic effect is aimed at normalizing the pressure indices inside the eye by reducing the production of intraocular fluid.
Unlike the Dorzopt preparation, drops of Dorzopt Plus are more effective and expressed lowering the intraocular pressure.
Included in the drug Dorzolamide belongs to selective inhibitors of carbonic anhydrase type 2. Timolol is a beta-adrenoblocker, which stimulates the increase in fluid outflow from the eyeball.
The therapeutic effect of the patient develops 20 minutes after instillation of the drug into the conjunctival sac and lasts up to 24 hours.

Indications for use

The main indications for prescribing Dorzopt Plus are:
    Open angle glaucoma;
    Pseudoexfoliation glaucoma.

Contraindications to use

The drug has serious limitations to the use, so before starting therapy should be screened by an ophthalmologist. According to the instructions, the following conditions are contraindications for the use of drops in the eye:
    Chronic obstructive pulmonary disease of severe course;
    Bronchial asthma in history;
    Violation of cardiac conduction, changes in the rhythm of the heart;
    Heart failure in the stage of decompensation;
    The period of pregnancy and breastfeeding;
    The patient's age is 18 years;
    Cardiogenic shock;
    Acute myocardial infarction;
    Renal failure of severe course;
    Degenerative changes in the cornea;
    Individual intolerance to the components of the drug.
Drops Dorzopt plus with particular caution are prescribed for patients with diabetes mellitus, hepatic insufficiency or persons of retirement age.

Dosing and Administration

Drops Dorzopt plus are designed to treat patients older than 18 years. The drug is instilled in the conjunctival sac 1 drop every 1-2 times a day, depending on the degree of expression of glaucoma. The duration of the course of therapy with a medicine is determined by an ophthalmologist.
If several medications are prescribed for a patient, the interval between their instillations should be at least 10 minutes.
Use of the drug during pregnancy and breastfeeding
Drops Dorzopt Plus are contraindicated for use by women in the waiting period of the child. Clinical trials have not been conducted, so it is not known how the active substances of drops on the fetus act.
If necessary, the treatment of glaucoma in nursing mothers should resolve the issue of stopping breastfeeding.

Side effects of Dorzopt plus

During the use of droplets in the eyes of Dorzopt Plus, the following side effects may develop in patients:
    Inflammation of the eyelids, lacrimation, reddening of the mucous membrane of the eye, keratitis, iridocyclitis, hemorrhage, sensation of foreign body, burning, dry mucous membrane;
    Headaches, violation of the sensitivity of the limbs, rapid fatigue and lethargy;
    Development of angioedema, urticaria, skin itching, bronchospasm;
    Dryness in the mouth, swallowing in the throat;
    Omission of the upper eyelid, double vision;
    Tinnitus;
    Decreased sex drive;
    Systemic lupus erythematosus;
    Change in blood pressure, syncope, development of Raynaud's syndrome;
    Perhaps the development of anaphylactic shock.

Overdose

With prolonged use of the drug or exceeding the dose specified in the instruction, the patient develops symptoms of an overdose, which manifests an intensification of the above-described side effects, as well as depression of the function of the heart, liver, kidneys. Possible cardiac arrest.
Against the background of an overdose of eye drops Dorzopt plus in patients often develop acidosis, a change in the water-salt balance.
With the development of an overdose, the drug is immediately stopped, the patient is taken to the hospital. Treatment is symptomatic. Dialysis is not effective. Such patients need to constantly monitor the concentration of potassium in the blood and monitor the work of vital organs.

Interaction of Dorzopt Plus with other drugs

With the simultaneous use of Dorzopt plus drops with beta-blockers for oral administration, the patient is at increased risk of developing severe hypotension and the systemic side effects described above.
Simultaneous use of the drug with MAO inhibitors enhances the hypotensive effect of the drug.
It is not recommended at the same time to use eye drops with drugs from the group of carbonic anhydrase inhibitors, as this leads to an increased risk of acidosis and the above-described side effects and overdose.

special instructions

Before starting therapy with the drug, the patient must undergo a complete examination, including an electrocardiogram and a cardiologist's consultation. Patients who had a history of heart abnormalities should, for the duration of therapy, Dorsoptom Plus be under the strict supervision of specialists.
When wearing contact lenses, the drug is instilled only after they have been removed, since the preservative contained in the drops can settle on the lens material and have a toxic effect on the body. You can not insert the lenses back earlier than 15 minutes after using the drug.
The drug with particular caution is prescribed for patients with diabetes mellitus. During the period of drug therapy, such patients should constantly monitor the blood glucose level and, if necessary, adjust the dose of hypoglycemic agents.
If the patient is to have planned surgery, then the treatment with drops of Dorzopt plus is canceled 2 days before the surgery. The active substance of the drug can enhance the therapeutic effect of general anesthesia.
During treatment with this drug, the patient should refrain from driving by car and managing complex mechanisms that require increased concentration.
For elderly patients, the daily dose is determined by the doctor, perhaps it will be slightly lower than recommended in the manual.

Storage conditions

Drops Dorzopt Plus should be stored at room temperature out of the reach of children, avoiding heating or freezing. When suspensions or foreign matter appear in the vial, drops should be discarded even if the product has not expired.
The opened vial should be kept in the refrigerator and used within 14 days. If the drug has not been consumed, then it is thrown out and a new bottle is unsealed.

Terms of sell

To buy Dorzopt plus you don't need a prescription.