Maxitrol eye drops 5ml

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Instruction for Maxitrol

Composition

In one milliliter of eye drops there are 3500 units. neomycin sulfate and 6000 units. polymyxin (B) sulfate, as well as 1 mg dexamethasone and excipients: neutral additives, polysorbate 20, hydroxypropylmethylcellulose (0.5%), distilled water. As a preservative used benzalkoniya chloride 0.004 percent.

Form of issue

Eye drops are available in 5 ml vials with Drop-Teiner dropper. Each bottle is sealed in a cardboard box.

pharmachologic effect

Has a local antibacterial and anti-inflammatory effect.

Pharmacodynamics and pharmacokinetics

Eye drops Maxitrol is a combined preparation that is used in ophthalmology. Neomycin is able to disrupt protein synthesis (bactericidal action, development of resistance is slow and to a small extent) in bacteria such as:
    Staphylococcus aureus (Staphylococcus aureus);
    bacterium-pathogens of diphtheria (Corynebacterium diphtheriae);
    small pathogenic streptococcal bacteria (Streptococcus viridans);
    E. coli (Escherichia coli);
    a rod of Friedlander (Klepsiella pneumoniae);
    Proteus vulgaris (Proteus vulgaris);
    Gram-negative bacillus bacterium (Aerobacter aerogenes);
    Haemophilus influenzae.
In this neomycin is not active against pathogenic fungi, viruses and anaerobic flora.
The active substance of this drug - Polymyxin B sulfate acts by blocking the permeability of the cytoplasmic membrane of cells of a number of bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli and Friedlander bacillus, and Koch-Weeks bacillus, which causes conjunctivitis.
Dexamethasone is a glucocorticosteroid, which has anti-inflammatory, anti-allergic, anti-exudative and desensitizing effect. In combination with antibiotics significantly reduces the risk of infection.

Pharmacokinetics

Local application is characterized by a low level of systemic absorption.

Indications for use

Eye drops Maxitrol is usually used for various infections of the eyes and appendages:
    with blepharitis;
    conjunctivitis;
    keratoconjunctivitis;
    keratitis;
    iridocyclitis;
    and as a prophylaxis in the postoperative period with inflammation of the anterior part of the eye.

Contraindications

    hypersensitivity to the constituents of this drug;
    eye diseases caused by viruses: keratitis (herpes simplex) and chicken pox;
    fungal diseases of the eyes;
    mycobacterial infections of the eyes;
    tuberculosis of the eyes;
    shingles;
    state after the removal of the foreign body of the cornea;
    purulent infections of the eye and eyelids, which are caused by microorganisms resistant to neomycin, including a purulent corneal ulcer.
Caution should be used for glaucoma and cataract.

Side effects

Local side effects usually manifest in the form of allergic reactions, accompanied by itching, swelling of the eyelids and reddening of the conjunctiva.
The steroid component causes increased intraocular pressure, followed by the development of glaucoma, damage to the optic nerve and visual fields, a posterior cataract of the subcapsular type, a delay in the healing of wounds.
In addition, the course of treatment - more than 10 days requires monitoring of intraocular pressure;
In addition, it is possible that:
    secondary infection with glucocorticosteroids and antibiotics;
    fungal infection of the cornea with prolonged use of steroids, up to the formation of non-healing ulcers indicative of fungal infestation.

Instructions for the use of Maxitrol (Method and dosage)

Method of application: topically, in a conjunctival sac. Before use, it is necessary to shake the vial with drops, then - always close it.
Instructions for eye drops Maxitrol differs from the severity of the infection process:
    non-severe form - 1-2 cap. must be instilled every 4-6 hours;
    a serious infectious process - 1-2 cap. It is necessary to dig in every hour, in process of decrease in an inflammation it is possible to lower frequency of instilljatsij preparations.

Overdose

At the moment there are no recorded cases of overdose with topical application.

Interaction

If it is necessary to use other local ophthalmic means - the interval before using the next preparation should be at least 10 minutes.

Storage conditions

In a place inaccessible to children. Make sure that the temperature is between 8-30 ° Celsius and the bottle is in a vertical position.
Shelf life - Two years. After opening the bottle - up to 4 weeks.

Reviews about Maxitrol

Reviews of eye drops are few, since the drug is released in pharmacies only on prescription, but those who used Maxitrol note that it helps, does not burn eyes and does not cause other side and allergic reactions.