Oftan Catachrom 10ml

Instruction for eye drops Oftan Catachrom

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Eye drops Oftan Catachrom contain (per 1 ml): 20 mg of nicotinamide, 0.675 mg of cytochrome C, 2 mg of adenosine + additional ingredients (succinate sodium hexahydrate, disubstituted sodium 2-aqueous sodium phosphate, water, benzalkonium chloride, sorbitol, monosodium phosphate 2- water).

Form of issue

The drug is produced in plastic bottles, with a dropper, a volume of 10 ml. The medicine is a clear red solution. There is one bottle in the carton.

pharmachologic effect

Anti-inflammatory, antioxidant, nourishing.

Pharmacodynamics and pharmacokinetics

The therapeutic effect of taking drops is due to the combination of their constituent substances.
Cytochrome C neutralizes the effect of free radicals on the cornea of ​​the eye. The substance also directly affects the crystalline eye, reducing the risk of cataracts (by inhibiting the synthesis of the enzyme cytochrome oxidase). This component is cleaved in the epithelium of the crystal to the heme peptide.
Adenosine dilates blood vessels and helps restore normal microcirculation in the eye. Also, the outflow of toxins and the saturation of the blood with oxygen are normalized. The substance stops the inflammatory process in the conjunctiva, the cornea and the anterior parts of the eye, by stimulating the A2 receptors on the surface of the cell membranes. It should be noted that adenosine is one of the fundamental elements in the processes of DNA renewal and energy metabolism. Being a structural component of the enzyme glutathione reductase and NADP, this substance plays the role of an intermediary in the processes of reducing glutathione occurring in the crystal of the eye.
Nicotinamide is a part of NADP and NAD - the main metabolite of the eye crystal. It is proposed to reduce the rate of cataract development by increasing the number of metabolites.
Due to the fact that this drug is low-toxic it can be used as a prophylaxis and for the cessation of cataracts. The duration of treatment should be at least six months.
The medicine affects not only the crystalline. It is proved that the drug has anti-inflammatory, antioxidant, disinfectant and antibacterial effect on the surface of the eye, it can stop the development of various infectious diseases in the anterior part of the eyes. Also, the preparation moisturizes well and relieves fatigue.
Cytochrome C is not subjected to systemic absorption. Once in the body is completely metabolized to bilirubin, which in turn is excreted with bile.
Adenosine has the ability to penetrate deep into the cornea of ​​the eye and spread across all tissues. In the tissues of the body very quickly (in a couple of minutes) the substance turns into inosine, urate and xanthine, which are excreted through the kidneys.
Nicotinamide is rapidly absorbed, part of it is metabolized to nicotinic acid, and then to N-methyl nicotinamide. Both compounds are excreted by the kidneys.

Indications for use

Drops are prescribed for the prevention and treatment of cataracts of various origins.

Contraindications

Admission means contraindicated in allergies to any of the components of the drug, children and adolescents (persons under 18 years of age).

Side effects

Immediately after instillation, a tingling sensation in the eyes may or may be felt.
Possible:
    allergic reactions (conjunctivitis, pruritus, contact dermatitis);
    rashes and itching on the skin, congestion, swelling of the face and skin.
Very rarely can be observed:
    nausea, loss of consciousness, dyspnea;
    lowering of pressure, hot flushes, a feeling of heat, weakness.

Eye drops Oftan Catachrom, instruction (method and dosage)

The drug is used exclusively topically.
Before use, the vial cap should be turned, while pressing down, open the vial.
It is necessary to carefully remove the lower eyelid, look up and drip the medicine under the lower eyelid.
According to the instructions for use, appoint 1-2 drops, 3 times a day.
Duration of admission is usually determined by the attending physician. The course of treatment should be at least 6 months.

Overdose

No cases of overdose have been reported.
Due to a slight systemic absorption and rapid removal of the drug, with its ophthalmic use, an overdose is unlikely.
If the medicine was accidentally ingested, symptomatic therapy should be given.

Interaction

The drug interaction with other agents does not occur or was not observed.
A 15-minute interval between the use of various ophthalmic agents should be observed.

Storage conditions

Keep the bottle at a temperature of 8 to 15 degrees.
Shelf life - 3 years. After the first opening of the vial, the shelf life is reduced to 30 days.

special instructions

Before using drops, remove contact lenses and do not wear them for 15 minutes to avoid the penetration of benzalkonium chloride into the lens.
The medication is not intended for oral administration or as an injection.
The drug can not be used by patients with glaucoma.
To avoid contamination of the tip of the bottle, they should not touch the skin or mucous membrane of the eye.
After taking the remedy, a brief misting in the eyes is possible.

In pregnancy and lactation

There is insufficient clinical data on the use of the drug by pregnant or lactating women. In this regard, the use of drops is not recommended.

Reviews of Oftan Catachrom

Reviews about the eye drops of Oftan Catachrom are good. The drug stabilizes the lens of the eye, prevents cataracts from developing; well established itself as a preventive tool. Adverse reactions are extremely rare.