Oftaquix 0.5% 5ml

Oftaquix user manual

You can buy eye drops Oftaquix here

Composition

In 1 ml of the drug Oftaquix contains 5.12 mg of levofloxacin hemihydrate, which corresponds to 5 mg of pure levofloxacin.
Additional substances: sodium chloride, benzalkonium chloride, sodium hydroxide, hydrochloric acid, water.

Form of issue

Eye drops Oftaquix is ​​a light yellow or light salad solution.
5 ml of solution in a vial with a cap in the form of a dropper. One such bottle in a pack of cardboard.

pharmachologic effect

Antibacterial.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Chemically, levofloxacin is the L-isomer of the racemic drug of Ofloxacin. Antibacterial action is provided by the L-isomer Ofloxacin.
Antibacterial agent from the pharmacological group of fluoroquinolones inhibits the activity of topoisomerase of the second type of DNA-gyrase and topoisomerase of the fourth type of bacterial cells. The action in the cells of gram-negative microorganisms is directed mainly at the DNA-girase, and in gram-positive microorganisms - on the topoisomerase of the fourth type.
It is active against gram-negative aerobes: Haemophilus influenzae, Branchamella cataralis, Neisseria gonorrhoeae and Pseudomonas aeruginosa; Gram-positive aerobes: Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus.

Pharmacokinetics

After use, levofloxacin is well fixed in the lacrimal film. Usually the average concentration in the blood after 60 minutes after application is from 0.86-2.05 ng / ml.
The highest concentration of levofloxacin in the blood is fixed on the fourth day after two days of using the drug eight times a day.

Indications for use

    therapy of superficial infectious diseases of the eye, caused by sensitive microorganisms, in persons older than 1 year;
    prevention of complications after laser and surgical operations on the eye.

Contraindications

    sensitization to drugs from the group of fluoroquinolones;
    sensitization to the components of the drug;
    pregnancy or lactation period;
    It is necessary to use with caution the drops of Oftaquix in childhood.

Side effects

    most often occur: a burning sensation in the eye area, a decrease in visual acuity, revealing mucous cords;
    rarely appear: blepharitis, sprains in the form of papillae on the conjunctiva, edema of the eyelids, chemosis, unpleasant sensations in the eye area, pain or itching in the eye area, the development of follicles on the conjunctiva, contact dermatitis, conjunctival hyperemia, erythema eyelids, dry eye syndrome, photophobia, eye irritation and allergic reactions;
    other reactions: rhinitis and headache.

Instruction for the use of Oftaquix (Method and dosage)

Instructions for use on eye drops Oftaquix prescribes taking the drug topically, by digging into a diseased eye.
In the first 2 days, it is prescribed to instill 1 or 2 drops every two hours into the diseased eye, but not more than eight times a day. On the 3-5 day of therapy, 1 or 2 drops are injected into the diseased eye four times a day.
Duration of treatment should be determined by the attending physician and usually it is five days.

Overdose

The total amount of levofloxacin present in one vial of the drug is too small to cause an acute toxic reaction, including the cases of taking the contents of the vial inside. After topical application of an excessive dose of eye drops, rinse with clean water.

Interaction

There have been no separate studies on the pharmacological interaction of Oftaquix with other drugs.
The interaction characteristic of systemic use is clinically insignificant because of the low concentration of levofloxacin in the blood with topical application.

Storage conditions

Store at temperatures up to 25 degrees. Keep away from children.
Shelf life - Two years. After depressurizing the vial, drops can be used for three months.

special instructions

These eye drops can not be applied subconjunctivally or injected into the anterior chamber of the eyeball.
With the joint use of other ophthalmic agents, the break between their use should be more than 15 minutes.
Do not use this drug while using hydrophilic contact lenses.
To prevent contamination of the dropper and drug solution, do not touch the tip of the dropper bottle with near-orbital tissues.

Children

The drug is not allowed for children under 1 year.

In pregnancy and lactation

In these periods, the drug is prohibited for use.

Reviews about Oftaquix

The reviews report satisfaction with the result of treatment with the drug of the vast majority of patients who used Oftacwix as prescribed by the doctor. Among the shortcomings most often noted high price of this drug.