Sofradex eye/ear drops 5ml

Sofradex instruction

You can buy Sofradex here

Composition

The composition of drops (1 ml) includes 0.05 mg of gramicidin, 0.5 mg of dexamethasone, 5 mg of .ramicetin. Auxiliary compounds: lithium chloride, sodium citrate, citric acid monohydrate, ethanol 99.5%, phenylethanol, polysorbate 80, d / and water.

Form of issue

Ear drops of Sofradex are available in bottles with a dropper and made of dark glass, 5 ml in volume.
Sofradex eye drops are also available in bottles with a dropper of dark glass, a volume of 5 ml.

pharmachologic effect

The drug has antipruritic, anti-allergic, antibacterial and anti-inflammatory effect.

Pharmacodynamics and pharmacokinetics

The drug Sofradex has a bactericidal and antibacterial effect of a wide spectrum due to gramicidin and Framicetin, is active against such Gram-positive and Gram-negative microorganisms as:
    Staphylococcus epidermidis and aureus;
    Streptococcus pyogenes, pneumoniae and faecalis;
    Escherichia coli;
    Proteus spp .;
    Klebsiella spp .;
    Pseudomonas spp. and etc.
Anti-inflammatory, anti-allergic and antipruritic effect has a glucocorticoid - dexamethasone. As a result of instillation into the eye, pain sensations, burning sensation decrease, there is photophobia, lacrimation and other symptoms characteristic of pathological processes caused by the corresponding pathogens. In addition, it is also effective in adenoids.

Pharmacokinetics

    Local application leads to low systemic absorption.
    Framicetin sulfate is absorbed by inflamed skin or through open wounds. Entering the systemic blood stream, is exposed to rapid excretion of the kidneys with a half-life in unchanged form 2-3 hours.
    Dexamethasone is rapidly absorbed from the digestive tract, the half-life is 3.16 (6) hours.

Indications for use

Eyelid droplets are usually prescribed for superficial bacterial infections of the eyes with an inflammatory or allergic component, as well as blepharitis, eczema eczema, barley, allergic conjunctivitis, keratitis rosacea, scleritis, episcleritis, iridocyclitis, iritis.
Drops for the ears are effective in acute or chronic external otitis.

Contraindications

    viral, for example, herpetic infections;
    fungal infections;
    tuberculosis;
    glaucoma;
    suppurative inflammation of the eye tissues;
    hyperemia of the eye of unknown etiology;
    hypersensitivity;
    perforated tympanic membrane (for ear drops).

Side effects

    irritation, burning, itching, pain, dermatitis at the place of application;
    increased intraocular pressure;
    subcapsular cataract (possible with prolonged use);
    thinning of the cornea - more often with diseases of the cornea, sclera.
Ear and eye drops Sofradex, instructions for use (Method and dosage)

In ophthalmology

Drops for the eyes should be used 6 times or more (per day) for 1-2 drops. 2-3 drops are instilled into the ear 3-4 times a day. Instructions for use Sofredeks assumes a 7-day course of treatment.
Attention! For infants or young children, the dosage should be selected individually and the drug should be used with extreme caution, since large doses and prolonged therapy can cause unwanted systemic effects.

Application in ENT practice

It should be buried in the outer part of the auditory meatus 2-3 drops. 3-4 times a day, or - you can lay a gauze pad, moistened with a solution.
The drops in the ears of Sofradex are applied no more than 7 days, except for cases of visible positive dynamics. It should be remembered that GCS mask hidden infections, long-term use of antimicrobial agents contributes to the development of stable flora and superinfections.

Adenoid application

Treatment regimen: Bury the drops in the nose should be within 4-6 days to 6-8 cap. Then, in order to remove a protracted viral infection, long-term therapy with Cycloferon (10-15 days) in the form of inhalations through the nebulizer is necessary.

Overdose

With prolonged local administration of large doses, systemic effects may occur, in which case symptomatic treatment is necessary.
If oral solution of 10 ml of solution (contents of 2 bottles) was taken orally, then the occurrence of adverse reactions is unlikely.

Interaction

Do not combine framicetin sulfate with other antibiotic agents that have ototoxic and nephrotoxic effects (eg: Streptomycin, Gentamicin, Monomycin, Kanamycin).

Storage conditions

The temperature does not exceed +25 ° C. Outside of children's access.
Shelf life - 24 months After opening the package - less than 1 month.

special instructions

In connection with the temporary loss of clear vision, do not immediately after the instillation procedure to get behind the wheel of an auto, to start working with complex equipment or machines.

Children

For children younger than 7 years, the drug is contraindicated, since oppression of the function of the adrenal gland is possible.
Burying Sofradex in the nose of a child can be with adenoids, remembering that in future antiviral therapy will be required.

In pregnancy and lactation

In pregnancy, the drug is contraindicated, since safety of use is not established.

Reviews of Sofradex

Reviews about Sofradex are positive, especially praise the drug people who used it for infectious-inflammatory diseases. Eye drops for 4-5 days cope with the problem of barley, and the ear - with acute and chronic external otitis. There are certainly disadvantages - possible tingling and itching, increased intraocular pressure.