Timolol 0.5% 5ml

User manual for Timolol

You can buy Timolol eye drops online

Composition

1 ml eye drops contain 2.5 or 5 mg of active ingredient timolol in the form of maleate.

Form of issue

Eye drops.

pharmachologic effect

A remedy for glaucoma. Non-selective blocker of b-adrenergic receptors.

Pharmacodynamics and pharmacokinetics

The drug indiscriminately blocks beta-adrenoreceptors. Timolol is applied topically.
The action of the drug is aimed at reducing the intraocular pressure by reducing the amount of watery moisture formed, and partly increasing its outflow.
Timolol does not affect the diameter of the pupil, accommodation, does not impair visual acuity, does not affect the quality of night and color vision.
The drug begins to act in twenty minutes.

Indications for use

Timolol is prescribed for secondary glaucoma, open-angle glaucoma, closed-angle glaucoma, congenital glaucoma, intraocular hypertension, acute increase in intraocular pressure.

Contraindications

Timolol is contraindicated in dystrophic lesions of the cornea, intolerance of the components.
In bronchial asthma, COPD, breastfeeding, atrioventricular blockade, arterial hypotension, pulmonary insufficiency, pregnancy, atrophic rhinitis, diabetes, during the neonatal period, severe form of cerebrovascular insufficiency is prescribed with caution.

Side effects

Lachrymation, conjunctival irritation, photophobia, pruritus, conjunctival hyperemia, keratitis, blepharitis, corneal epithelial edema, punctate keratopathy, ptosis, diplopia.
Among the systemic reactions, bradycardia, collapse, a drop in blood pressure, rhinitis, paresthesia, nosebleeds, nasal congestion, drowsiness, dyspnea, myasthenia, depression, hallucinations, diarrhea, vomiting, nausea, ringing in the ears, allergies can be noted.

Eye drops Timolol, instructions for use (Method and dosage)

The drug is instilled twice daily in each conjunctival sac by one drop (0.25% solution).
If necessary, the concentration of the solution is increased to 0.5%.
According to the instructions for the use of Timolol, after normalization and stabilization of intraocular pressure, they pass to maintenance therapy: once a day, one drop (0.25% solution).

Overdose

General obesity effects, typical for many beta-blockers: bronchospasm, bradycardia, headaches, dizziness, vomiting, arrhythmia develop.
It is recommended that the eyes be washed with a solution of sodium chloride and water in a timely manner. Further treatment is asymptomatic.

Interaction

Beta-blockers of systemic action, pilocarpine, epinephrine increase the effectiveness of Timolol.
Impossible simultaneous use with neuroleptics (antipsychotics), tranquilizers (anxiolytics).
Timolol increases the effectiveness of general anesthetics, muscle relaxants.
It is recommended to abandon the intravenous administration of Diltiazem, Verapamil in view of the high probability of falling blood pressure, the development of bradycardia, and depression of AV-conduction.
It is unacceptable to drink alcohol-containing beverages.
With caution appoint with insulin, beta-adrenoblockers, glucocorticosteroids.

Storage conditions

In a dark place inaccessible to children at a temperature of no more than 25 degrees Celsius
Shelf life - Not more than two years.

special instructions

It is recommended to avoid activities that require good vision in the dark. Care must be taken when driving in the dark.
Control of the effectiveness of treatment is carried out in three weeks. Long-term therapy can lead to a weakening of the drug Timolol.
Treatment requires regular monitoring of tear production, evaluation of the integrity of the cornea. It is recommended to stably evaluate the magnitude of the fields of vision. Once a month, the intraocular pressure is measured.
Preservative of the drug is deposited on contact lenses.

Reviews about Timolol

The drug effectively reduces eye pressure (including glaucoma), relieves pain in the eyes, helping to avoid deterioration of vision.
They have eye drops of Timolol and negative reviews. It is noted that the drug over time helps worse, and also has side effects.