Penester tabs 5mg #90

Penester instruction for use

Reed more and buy Penester on this page

Composition

One tablet of the drug Penester includes 5 mg finasteride.
Additional components: lactose monohydrate, povidone K30, corn starch, sodium docomate, sodium carboxymethyl starch, magnesium stearate.
Sheath composition: talcum, hypromellose 2910/5, emetic simethicone SE4, macrogol 6000, titanium dioxide, dye yellow.

Form of issue

Biconvex pale yellow tablets of round shape.
    10 tablets in a blister - three blisters in a pack of cardboard.
    15 tablets in a blister - six or two blisters in a pack of cardboard.

pharmachologic effect

Inhibits the reductase of testosterone.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

A means for treating benign prostatic hyperplasia, an artificially created 4-azasteroid compound. Competitive and selective blocker of 5-alpha reductase steroid - an intracellular enzyme that transforms testosterone into a physiologically active form of 5-dihydrotestosterone. The growth of the prostate and the increase in its size are caused by the conversion of the testosterone hormone to dihydrotestosterone in the prostate gland. Under the action of the drug there is a marked decrease in the level of dihydrosterone. Penester does not bind to androgen receptors.
As a result of using the medication, the prostate gland decreases, the symptoms of prostate hyperplasia decrease.
Does not change the level of blood lipids, as well as the concentration in the blood of cortisol, thyroid-stimulating hormone, prolactin, estradiol, thyroxine.

Pharmacokinetics

After use, the drug is quickly absorbed from the intestine. Bioavailability reaches 80% and does not change under the influence of food intake. The time of the greatest concentration in the blood is 1-2 hours. Reacting with plasma proteins - up to 90%.
Finasteride is transformed in the liver and is excreted in the form of derivatives with urine and feces. The half-life of people from 60 years - 6 hours, in persons from 70 years - about 8 hours.

Indications for use

Therapy of prostate adenoma (to reduce the volume of the prostate gland, increase the maximum rate of urinary retention and alleviate the symptoms caused by hyperplasia, and reduce the risk of acute urinary retention).

Contraindications

    prostate cancer;
    closure or sharp narrowing of the lumen of the urinary tract;
    sensitization to the components of the drug;
    childhood.
It is recommended to prescribe with caution the drug for disorders of liver function.

Side effects

    Changes from the genital area: breast tenderness, gynecomastia, impotence, decreased libido and a decrease in ejaculate volume.
    Other reactions: allergic phenomena.

Penester, instructions for use (Method and dosage)

Means are taken regardless of the meal.
Usually the medicine is prescribed to take 5 mg daily. The duration of therapy before evaluating its results should be at least six months. Approximately half of the patients during the year of treatment experienced the disappearance of the symptoms of the disease.

Overdose

There are no reports of an overdose of the drug.

Interaction

Clinically significant reactions of finasteride with other drugs have not been recorded.

Terms of sale

To buy Penester you don't need a prescription.

Storage conditions

Store in a dark place at room temperature. Keep away from children.
Shelf life - 2 years.

special instructions

Before the beginning of treatment it is necessary to exclude diseases that can simulate adenoma of the prostate gland: urethral stricture, prostate cancer, infectious prostatitis, bladder hypotension and some changes in the genitourinary area provoked by a number of diseases of the nervous system.
Since with the use of finasteride, a decrease in the prostate-specific antigen is often observed, in the course of therapy it is necessary to regularly check patients to exclude malignant diseases of the prostate gland.

Children

The drug is not used in children.

In pregnancy and lactation

It is forbidden to use the drug and contact with crushed tablets during the periods indicated.

Reviews about Penester

Reviews of Penester on the forums generally positively assess the effect of the drug, but side effects in the form of dilution of ejaculate or other phenomena develop in the vast majority of patients.