Decaris tabs 150mg #1

Instruction for Decaris

You can buy Decaris tablets on this page

Composition

Levamisole hydrochloride, corn starch, sodium saccharin, talc, povidone, apricot flavor, magnesium stearate, yellow dye.

Form release

Tablets-flat, round shape, light orange color 50 and 150 mg blister contour package №1 and 2 in a cardboard bundle.

Pharmacological action

De-worming.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Wikipedia defines Decaris as an anthelmintic agent with immunomodulatory effects. The drug depolarize muscle membrane of worms, inhibits enzymatic activity futuretweets and of succinate dehydrogenase, inhibits bioenergetic processes. Paralyzed nematodes are removed from the body by intestinal peristalsis within 24 hours after taking the drug.
The immunomodulatory effect of the drug is manifested by increased production of antibodies to antigens and T-cell response, activation of T-lymphocytes, increased function of macrophages, monocytes and neutrophils (phagocytosis, chemotaxis and adhesion).

Pharmacokinetics

When ingested, the drug is rapidly absorbed from the gastrointestinal tract. Smax in the blood after administration of the drug is achieved in 1.5 - 2 hours. Levamisole metabolism occurs in the liver, its metabolites are glucuronide and hydroxy-levamisole. The half-life is 3-6 hours. It is released in the form of metabolites with urine and feces.

Indications for use

Infection with helminths (hookworm, ascariasis, necatoroz, Trichostrongylus, trihozefalez, strongyloidiasis, enterobiasis, toxoplasmosis).

Contraindications

high sensitivity to the drug;
agranulocytosis a history of drug-induced;
the age of 3 years;
period of pregnancy and lactation.
Take care when oppression kostnomozgovy blood, liver and kidney failure.

Side effect

Insomnia, headache, dizziness, convulsions, palpitations, encephalopathy, dyspeptic disorders, skin rash, leukopenia, agranulocytosis, tremor.

Pills Decaris, usage instructions (Method and dosage)

Adults should be taken orally with a meal at the next dose:
In toxoplasmosis: once at one time 150 mg per day for three days. If necessary, the course of treatment can be repeated intermittently in one 1 week.
In helminthiasis: once, before bedtime at a dose of 150 mg for adults and at a rate of 2.5 mg / kg for children. If necessary, the course can be repeated again in 1-2 weeks.
Instructions for use Decaris indicates the need to study peripheral blood before treatment, and during treatment – the control of the number of leukocytes. During the reception of the drug and after, for one day, it is strictly forbidden to drink alcoholic beverages.

Overdose

When taking a high dose (more than 600 mg) may appear signs of intoxication in the form of nausea, vomiting, headache, dizziness, drowsiness, diarrhea, seizures and confusion.

Interaction

Decaris should not be taken with ethanol, lipophilic compounds (carbon tetrachloride, oil chenopodia, tetrachloroethylene, chloroform) and drugs that cause leukopenia.
The drug enhances the effect of indirect anticoagulants and phenytoin.

Terms of sale

To buy Decaris the prescription is not required.

Storage conditions

At a temperature of 15-25°C.
Shelf life - 60 months.

Decaris for children

Decaris for children, given the large number of possible side effects in the treatment of helminthiasis, can be taken only after consultation with a doctor. Tablets for children are available at a dose of 50 mg levamisole.
How to take the drug to children? One tablet (50 mg) is calculated on 10 kg of weight of the child. Instructions on the drug contains the calculation of the dosage for children. Indicative dosage children from 3 to 6 years account for 25-50 mg; from 6 to 10 —50-75 mg; from 10 to 14 years — 75-100 mg. However, calculation of dosage by weight child's is more accurate and reduces the likelihood of side effects.

Decaris to enhance immunity

To boost immunity in children is almost never used. There are many modern high-performance and relatively safe immunomodulators that your child will be prescribed by a doctor if necessary. Reviews about taking Decaris in children in most cases positive. Judging by them, side effects in children occur less often than in adults. This is probably due to the fact that parents, giving Decaris from worms to the child, strictly observe the dosage prescribed by the doctor. In the reviews, there is a good anti-leaf effect of Decaris, and the convenience of a single reception.

Feedback about the Decaris

Reviews about the drug are quite different. Many patients, taking decaris tablets from worms, note the strong side effects in the form of odor, severe nausea, headaches, dizziness, vomiting and skin rashes. Because of this, some parents are afraid to give to children. But in most cases, complaints about the inefficiency of the drug, both for adults and for children in the treatment of helminthic infestations are absent.
Many website visitors are interested in how worms come out after taking the drug. Helminths, who died of paralysis, are removed from the body within a day after taking the drug in a natural way (through the intestine with feces). Some ask, what pills Decaris assigned, meaning what kinds of worms it works. The drug is effective against nematodes (round worms) which include ascarids, pinworms, Trichinella, Toxocara, vlasoglav.

Decaris, doctor reviews

Doctors mostly speak favorably about Decaris, noting its high efficiency:
"...in the practice of the doctor of rural out-patient clinic Decaris I apply quite often. Many patients, having read negative reviews on the Internet, are afraid to take the drug. Have them sometimes for a long time to dissuade. In my personal, almost ten-year practice, there have been only a few cases of moderate consequences. Most people tolerate the recommended dose of the drug completely normal. I personally and my family as a preventive measure take Decaris (live in the house 3 cats and a dog) for almost 7 years. And no serious complications were observed. It should be remembered that the phenomena of headache and nausea are a consequence of intoxication of the body, formed due to the difficulties of emptying the intestine. To this end, you can take a laxative drug, and the drug must be taken at night, then the side effects of the patient practically does not notice."