Furacilin alcohol solution 0.067% 1:1500 10ml

Furacilin solution instruction for use

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Composition

In alcohol solution as an auxiliary component is 70% ethanol. The active substance and ethanol are contained in a ratio of 1: 1500.
Furacilin is also part of a number of medicines combined composition.
So, for example, complex drops with Furatsilin are used to treat a protracted runny nose, an antiseptic sponge with Gentamycin and furatsilin - as a disinfectant for infectious lesions of bones and soft tissues (as well as for prevention of purulent complications after operations on bones).

Form of issue

    Alcohol solution 0.067% for local / external use (10 and 25 ml each in dark glass bottles).
The certified standard nitrofural sample corresponds to the fitness requirements and requirements of the ISO of the Pharmacopoeia of Ukraine, the Russian Federation, the United States, Great Britain, and the European Pharmacopoeia.

pharmachologic effect

Antimicrobial.

Pharmacodynamics and pharmacokinetics

What is nitrofural?

Nitrofural is a derivative of nitrofuran, which is yellow or yellow with a greenish tinge, a bitter-tasting, fine-crystalline powder.
The powder is almost insoluble in ether, slightly soluble in ethanol and water, but readily soluble in alkali solutions.
The gross formula of nitrofural is C6H6N4O4.
Wikipedia indicates that one of the properties of nitrofuran compounds is photosensitivity. Therefore, the diluted solution should not be exposed to daylight. Particularly harmful for solutions of furacilin UV rays, which deeply and irreversibly damage the molecule of nitrofural.

Pharmacodynamics

The properties of nitrofurans are due to the presence in their molecule of an aromatic nitro group, which is similar to the chloramphenicol (levomycetin) present in the molecule.
The mechanism of action of nitrofural is different from the mechanism of action of other chemotherapeutic drugs: under the influence of nitrofural from proteins of microbial cells (flavoproteins), amino derivatives that are highly reactive are formed, which have the ability to change the conformation of macromolecules (including ribosomal proteins).
As a result, the tertiary and quaternary structure of the protein is deformed, the flow of metabolic processes in the microbial cell is disrupted, and the cell dies.
The substance increases the absorption capacity of the macrophagic (reticuloendothelial) system and promotes the enhancement of phagocytosis.
Nitrofural is effective against Gram (+) and Gram (-) bacteria, as well as against some protozoa and viruses. Sensitive to the drug are: Shigella (Sh. Dysenteriae, flexneri, boydii, sonnei), Escherichia coli, Streptococcus, Staphylococcus, Salmonella, Clostridium Perfringence.
Resistance to nitrofural develops slowly, while it does not reach a high degree. The drug is effective in the resistance of pathogenic microflora in other antimicrobial drugs (which are not derivatives of nitrofuran).
Nevertheless, in the hospitals there are completely resistant to nitrofural strains of microorganisms.

Pharmacokinetics

With external and local application nitrofural is absorbed in very small amounts. The substance penetrates through the histiocytic barriers and is evenly distributed in the physiological fluids and tissues of the body.
Metabolized nitrofural mainly by reducing the nitro group. The excretion of metabolic products is carried out by the kidneys, in addition, in part they are ex- tracted with bile.
Indication for the use of furacilin

What is nitrofural used for?

Nitrofural is an antimicrobial agent used to prevent the decomposition process on the surface of open wounds, to rinse cavities, as well as to treat microbial lesions of ENT organs and eyes.

Indication for the use of furacilin:

    fresh and complicated by pyogenic infection (purulent) wounds;
    pressure sores;
    burns 2 and 3 degrees;
    minor damage to the skin (cracks, abrasions, cuts, etc.);
    osteomyelitis;
    inflammation of the outer shell of the eye or ciliary edge of the eyelids;
    purulent inflammation of the glands (sulfuric or sebaceous) and the hair bulb of the external auditory canal;
    acute otitis media (middle or outer);
    inflammatory processes in the oral cavity (gingivitis, stomatitis);
    purulent-inflammatory lesions of the pleural and articular cavities.
In addition, the preparation is used to treat the granulating surface before the procedure of skin transplantation.
Tablets of 20 mg are used for the preparation of solutions (aqueous or alcoholic). Application of furacilin in tablets is indicated in bedsores, purulent wounds, ulcerative lesions, osteomyelitis, burns (2 and 3 items), anaerobic infection, chronic purulent otitis, purulent pleurisy.

Furacilin: what helps the aqueous solution and when an alcohol solution is prescribed?

The aqueous solution is intended for:
    disinfection of cavities in sinusitis, purulent pleurisy and after operations on the bones (for example, with osteomyelitis);
    rinsing of the urethra and bladder;
    rinsing of the mouth and throat caused by infections that are sensitive to nitrofurale;
    eye rashes with conjunctivitis or blepharitis.
The use of a solution of furacilin (alcohol) is indicated for inflammation of the middle ear.

Contraindications

The use of furacilin is contraindicated in cases of intolerance to nitrofural or auxiliary components of the drug, dermatoses and pathological conditions accompanied by bleeding.

Side effects

With external application of furacilin, dermatitis and hypersensitivity reactions are possible.
In some cases, inflammatory skin damage is the reason for the temporary cessation of treatment, in others - the basis for the complete withdrawal of the drug.
When ingestion possible dizziness, nausea, decreased appetite, vomiting, allergic reactions.

Instructions for use Furacilin

The use of a solution for treating wound surfaces and rinsing cavities
To clean the wounds, only a sterile solution of furacilin can be used. That is, if the medicine is prepared at home, it is boiled for 30 minutes and used from the same container in which it was cooked.
The wound should be treated with a weak stream of cooled solution.
The drug can also be used for dressing wounds as a means for soaking the adherent dressings.
When purulent pleurisy sterile aqueous solution is injected into 20-100 ml into the pleural cavity, after purulent exudate is removed from it.
In osteomyelitis after surgery, Furacilin is washed with a cavity, and then a moist bandage is applied.
When preparing for a skin transplant operation, the drug is used to irrigate the affected parts of the skin, and then cover the wound surface with a moist dressing.

Can I gargle with Thuracilin?

Gargling with Thuracilin is a good help for tonsillitis and tonsillitis. The drug, of course, does not replace antibiotic therapy and other medical measures, but it can significantly alleviate the patient's condition and accelerate recovery.
This is due to the fact that regular rinses with angina promote leaching of pathogenic microflora and pus. In addition, acting as an antiseptic, furacilin stops the growth and multiplication of bacteria.
An aqueous solution of Thuracilin for gargling can be used for any type of disease, regardless of which microorganism is its causative agent.
An important property of the drug is that, when applied topically, it is almost not absorbed into the blood, so it can be used even in young children (provided that they can gargle themselves) and in pregnant women.
How to dilute Furacilin for gargling and how to gargle properly with sore throat?
Furacilin with angina is used in the form of a solution, for the preparation of which one powdered tablet of the drug (20 mg) is filled with half a glass (100 ml) of boiling distilled water. To enhance the therapeutic effect in the drug, when it cools down, add 2 teaspoons of 3% hydrogen peroxide.
Gargling with Thuracilin for angina is done for 3-5 minutes, using for each procedure half a glass of solution (the temperature of the liquid should be close to body temperature).
Before gargling with Thuracilin, you can rinse with a soda solution. This will remove the accumulated mucus and increase the effectiveness of treatment with Furacilin.
Use the tablets to rinse your throat can be up to 10 rubles a day.
The principal difference between how to grow Furacilin for gargling is adult and child is not. It should be remembered that even a child who knows how to gargle independently should perform this procedure under the supervision of an adult.
There is also a way how to gargle Thuracilin's baby's throat, which can not yet do it himself. In order to remove the plaque and bacteria from the throat, the child should be tilted over the bath and rinsed out of the syringe with a solution with a sore throat.

How to prepare a solution of furatsilina for otitis treatment?

Inflammation of the middle ear is treated with alcohol solution, which is prepared on the basis of 70% ethanol.
To make the medicine at home, three tablets of the drug are ground into a powder and poured into half a glass (100 ml) of ethyl alcohol. Before use, the solution should be infused for 2-3 hours.
According to the instructions for use, the alcohol solution of furacil should be injected into the ear canal, pre-heating the medicine to body temperature. Single dose - 5-6 drops.

Can I wash my nose with Furacilin?

Furacilin is often used to wash the nose. The benefit of the nasal shower is that it allows you to remove from the surface of the mucous pathological secret, dust, the products of vital activity of pathogenic bacteria and allergens.
After such a procedure, the inflammation and edema of the nasal mucosa decreases, the function of the cells of the ciliated epithelium and the tone of the capillaries of the nose improve, the movement of mucus increases and, as a consequence, the body's ability to resist infections increases.
The use of the drug is advisable as an aid in frontitis and sinusitis.
To wash the nose with Furacilin for sinusitis, you can use an aqueous solution (pharmacy or prepared by yourself) or a paste that is diluted 1: 1 with sterile water before use.
It is necessary to monitor the correctness of the performance of the nasal shower, since incorrectly done washing can cause germs to enter the eustachian tubes and sinuses of the nose.
It is best to use a specially designed device for this purpose, but you can replace it with a small teapot.
The solution is heated to room temperature, then leans over the sink and slowly pours in the liquid at first, and then into the second nasal passage. After the nasal shower is completed, the remnants of the solution should be blown out.
In order not to exacerbate the course of the disease, during the cold season you should not go out for 2 hours, and in the warm season - for 30 minutes after washing the nasal cavity.
Nasal shower is contraindicated in acute otitis, obstruction of nasal passages, propensity to nosebleeds, presence of neoplasms in the nasal cavity.

Can I wash my eyes with Furacilin?

Furacilin is a good helper when it comes to inflammatory diseases of the conjunctiva. The advantage of the drug is the possibility of application in pediatrics.
To prepare a furacilin solution for the eyes, two powdered 20 mg tablets are poured into a glass of hot water and, after stirring occasionally, cooled to room temperature. After this, the solution should be filtered, since even small crystals can injure the mucous eyes.
For straining the medicine, a sterile gauze folded several times is used.
All manipulations must be carried out with clean hands.
Clean the cotton pad dipped into the solution and squeezed. After that, pulling the lower eyelid, they rub the mucous membrane of the eye.
The direction of movement is from the inner corner of the eye to the outer corner. This will avoid the spread of infection to healthy tissue.
The medicine can also be injected into the eye with a special funnel.

Furacilin from acne

For the treatment of problem skin, the solution can be used in two ways: in pure form or in combination with tooth powder and calendula tincture.
In the first case, furacilin is used instead of a tonic for rubbing the skin after each washing. Wiping your face, you should especially stay on the affected areas of the skin.
To prepare furatsilinovoj ointments from spots it is necessary to take 1 part of a solution (tablet Furatsilina on a glass of water), 1 part of tincture of calendula and 1 part of tooth powder. All components are mixed and applied pointwise to inflamed elements on the face.
The duration of exposure is 15 minutes. After this time, you need to wash your face.

What happens if you drink a solution or swallow a pill?

The ingestion of a small amount of solution when rinsing the throat poses no threat to health.
Also, do not worry if you accidentally drank 1-2 tablets of the drug. There are situations when they are appointed to take inwards, therefore, in the absence of clinical manifestations of poisoning, this is also not terrible.
If the taken dose is much higher than recommended, you should induce vomiting, rinse the stomach with a suspension of activated charcoal and call a doctor. Also, the affected person should be given an isotonic solution of sodium hypochlorite.
The most likely side effects of oral administration of furacilin are nausea, weakness, dizziness and vomiting. With a severe overdose, there may be dyspeptic disorders, a violation of vitamin synthesis, dysbacteriosis, hepatitis, nephritis, polyneuropathy and peripheral neuritis.

Overdose

Overdose can be manifested by increased severity of side effects.

Interaction

Negative drug interactions are not described.

Terms of sale

Without recipe.

Storage conditions

Store at temperatures up to 25 ° C. The solution must be protected from exposure to daylight and ultraviolet rays.

Shelf life

Tablets for external use - five years. Tablets for oral administration - four years. Alcohol solution and ointment - two years.

Furacilin for newborns

Furacilin is one of the most commonly used remedies for conjunctivitis in children.
In the presence of secretions from the eyes, the solution for the eyes of newborns can be used already from the first days of life.

How to grow Furacilin for washing the eyes of a baby?

To prepare a solution for the treatment of the eyes of newborns, 1 tablet of the drug is dissolved in a quarter of a liter of boiling water. The medicine is used in the daily morning toilet of the child.

How to wash the eyes of a newborn?

The procedure is carried out as follows: the cotton disc is wetted in a room temperature solution, lightly squeezed, and then rubs the child's eye in the direction from the inner corner to the outer corner. For each eye should be a separate wadded disk.
If the number of secretions does not decrease after a day or two, it is necessary to consult a doctor.

Furacilin in pregnancy

A feature of nitrofural is that it does not enter the blood when applied topically / topically. This property allows you to use the drug in pregnancy, when most other drugs are contraindicated.
Rinses Furacilin during pregnancy are indicated for inflammatory diseases and bacterial infections of the mouth and throat, as well as for sinusitis and frontitis.
In addition, the aqueous solution can be used to wash and syringate with vaginal candidiasis, and ointment and paste - to treat minor injuries of the skin and mucous membranes.
Despite the fact that the drug does not harm the future mother's body and its child during external application, it is still necessary to use it for the intended purpose and in accordance with the prescriptions of the doctor.
In addition, when rinsing your throat during pregnancy, you should avoid swallowing the medication.

Reviews of Furacilin

Finding bad reviews about Furacilin is very difficult. The drug has proved to be an effective antimicrobial agent with a wide spectrum of action that is not only available but can be used even in infants and pregnant women.