Zorex morning tabs #10
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Buy Zorex morning tablets onlineZorex morning instructionCompositionEach tablet contains 0.324 g of acetylsalicylic acid, 1.474 g of citric acid, 2.013 g of sodium hydrogen carbonate, as well as auxiliary substances: 0.08 g of suc..
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Buy Zorex morning tablets online
Zorex morning instruction
Composition
Each tablet contains 0.324 g of acetylsalicylic acid, 1.474 g of citric acid, 2.013 g of sodium hydrogen carbonate, as well as auxiliary substances: 0.08 g of succinic acid, 0.048 g of sodium benzoate, 0.001 g of povidone, 0.04 g of lemon flavor and 0.02 g flavoring "lime".
Form of issue
It is issued in the form of effervescent tablets, 2 pieces in contour non-jawed packages (strips), manufactured by combined material, the tablets in the strip are divided among themselves by perforation. Scrubs put on 5 pieces in cardboard packs.
pharmachologic effect
Zorex Morning has analgesic, antipyretic and anti-inflammatory effect.
Pharmacodynamics and pharmacokinetics
Pharmacodynamics
The drug Zorex Morning refers to non-steroidal anti-inflammatory drugs with a combined composition. Acetylsalicylic acid has an inhibitory effect on cyclooxygenase 1 and 2 and as a result disrupts the synthesis of prostaglandins, has an anti-inflammatory, antipyretic, analgesic effect, slows the aggregation of platelets.
Sodium bicarbonate plays an important role in neutralizing free hydrochloric acid in the stomach. This is necessary to reduce the risk of negative consequences as a result of the use of acetylsalicylic acid.
The role of citric acid is to accelerate the absorption of the medication from the digestive tract.
Pharmacokinetics
At the present time there is no data on the pharmacokinetics of Zorex Morning.
Indications for use
To the indications for the use of the drug Zorex Morning include:
headache that occurs in the case of alcohol withdrawal syndrome;
a mild or moderate manifestation of the pain syndrome in adults, which has a different origin (for example, migraine pain, toothache, neuralgia, muscle pain);
elevated body temperature with the development of colds or other infectious-inflammatory diseases (in persons who have reached the age of 15).
Contraindications
Zorex Morning is forbidden to take at:
erosive and ulcerative lesions of the gastrointestinal tract (during an exacerbation), gastrointestinal bleeding;
"Aspirin" asthma;
combined with methotrexate in a dose of 15 mg per week;
expressed violations of liver function;
severe renal dysfunction;
hemorrhagic diathesis (this group includes all types of hemophilia, telangiectasia, von Willebrand's disease, hypoprothrombinemia, thrombocytopenic purpura, thrombocytopenia);
exfoliating aortic aneurysm;
deficiency of glucose-6-phosphate dehydrogenase;
portal hypertension;
pregnancy (during the I and III trimester);
breastfeeding;
hypersensitivity to acetylsalicylic acid and other non-steroidal anti-inflammatory drugs.
The drug can not be prescribed as an antipyretic agent for those who have not reached the age of 15, especially in cases of development of acute respiratory diseases that were caused by viruses, since in such cases there is a considerable risk of the appearance of Reye's syndrome, which is manifested by encephalopathy and acute fatty dystrophy of the liver, and rapid development of acute hepatic insufficiency.
Care should be taken when using the drug in patients with hyperuricemia, urate nephrolithiasis, gout, peptic ulcer of the stomach and duodenum (both in the case of exacerbations, and if there are any references to these diseases in the anamnesis). Also, with caution, prescribe the drug in cases of having a heart failure in the stage of decompensation.
Side effects
The drug has an effect on the body as a whole, so many body systems can exhibit unwanted symptoms caused by the side effect of the drug:
Digestive system: Appetite may drop significantly, abdominal pain, stomach pain, nausea, vomiting, diarrhea, signs of bleeding in the gastrointestinal tract. Signs of bleeding may be obvious (for example, black stool, bloody vomiting), but may be hidden. But in any case there is a danger of developing iron deficiency anemia. It is also possible the occurrence of erosive-ulcerative lesions of the gastrointestinal tract, even with perforation. In rare cases, a disruption of liver function, which is manifested by increased levels of hepatic transaminases and bilirubin.
Central nervous system and sensory organs: There may be dizziness, noise in the ears. In cases where the drug is taken for a long period of time, probably the occurrence of a headache, visual and hearing impairments.
System of hematopoiesis and hemostasis: A side effect of the drug may be the development of aplastic anemia, agranulocytosis, pancytopenia, hemorrhagic syndrome, thrombocytopenia. If the medication is taken for a long time, the level of platelet aggregation and the rate of blood clotting may decrease (development of hypocoagulation).
The urinary system: As a result of the use of high doses of the drug, it is possible to develop hyperoxalaturia and the formation of urinary stones from calcium oxalate, the glomerular apparatus of the kidneys may be damaged, kidney failure may develop; and with prolonged use of the drug - papillary necrosis.
It is also possible to develop allergic reactions: skin rash, Quincke's edema, bronchospasm, Stevens-Johnson syndrome, toxic epidermal necrolysis (or Lyell's syndrome).
Instructions for the use of Zorex Morning (Method and dosage)
Pills Zorex Morning take inside. For this, the tablet is dissolved in a glass of water and drunk. Single dose for adults and children aged 15 years - 1-2 tablets with a break between doses from 4 to 8 hours. The maximum allowable dose for a day is 8 tablets.
According to instructions on Zorex Morning, the length of the treatment period should not be more than 7 days in the case when the drug is prescribed as an anesthetic, and not exceed 3 days if used as an antipyretic.
Overdose
The first symptoms of overdose are signs of excitation of the central nervous system, the appearance of dizziness, severe headache, gastralgia, ringing in the ears, lowering of the severity of hearing, impaired vision, nausea, vomiting, dyspnea. In the following stages, a sensation of drowsiness, convulsive states, anuria is characteristic, consciousness is suppressed until the onset of coma, the development of respiratory failure, disturbance of water-electrolyte metabolism.
If signs of poisoning appear, it is necessary to induce vomiting or rinse the stomach, then drink the required amount of tablets of activated carbon or another drug with a similar effect, drink a laxative and seek medical help from a doctor. Further treatment is carried out in a specialized department.
Interaction
The drug has the property of increasing the toxicity of methotrexate, causing an increase in the effect of opioid analgesics, other non-steroidal anti-inflammatory drugs, heparin, certain types of anticoagulants, sulfonamides, thrombolytic agents, platelet aggregation inhibitors, triiodothyronine, reserpine. It also reduces the effect of uricosuric drugs (such as benzbromarone and sulfinpyrazone), blood pressure lowering agents, and diuretics (eg, spironolactone, furosemide).
The use of glucocorticosteroids, ethanol or ethanol-containing drugs in conjunction with Zorex tablets Morning causes an increase in the damaging effect on the mucous membrane of the gastrointestinal tract, increases the risk of gastrointestinal bleeding.
The drug increases the concentration in the blood plasma of barbiturates, digoxin, and also lithium preparations.
The use of antacids, which contain magnesium hydroxide or aluminum, leads to a slowing and deterioration in the absorption of acetylsalicylic acid.
Paracetamol increases the likelihood of unwanted side effects.
Terms of sale
It is allowed to sell without a prescription.
Storage conditions
In a dry place and protected from light. The air temperature should not exceed 25 ° C.
Shelf life - 3 years.
special instructions
Care should be taken when using the drug for people with a predisposition to gout, since acetylsalicylic acid, which is part of the drug, helps to reduce the excretion of uric acid from the body, and this can provoke an acute attack of this disease.
If the drug is used for a long time, it is necessary to monitor the condition of the peripheral blood, the functional state of the liver and check the presence of hidden blood in the analysis of stool.
It is worth remembering that in a single dose of the drug Zorex Morning contains 933 mg of sodium, so you need to apply with caution to people who are on a salt-free diet.
Children
Do not administer to children under 15 years of age.
With alcohol
The use of alcohol during treatment can provoke gastrointestinal bleeding.
In pregnancy and lactation
It is forbidden to use the drug during the I and III trimesters of pregnancy. During the second trimester of pregnancy, a single use of the drug is possible, but only in those cases where the risk to the fetus is less than the benefit for the pregnant woman.
If you need to apply the drug during lactation, for the period of treatment you need to stop breastfeeding.
Reviews
Reviews about the drug Zorex Morning a lot. Most often it is drunk as a pill from a hangover. There are reviews of its effectiveness, but there are also a lot of those that talk about the occurrence of side effects of the drug, especially allergic reactions.