Dimephosphon solution 15% 100ml

Dimephosphon instruction

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Composition

Dimephosphon includes dimethyloxobutylphosphonyl dimethylate as an active substance. The solution also contains purified water.

Form of issue

The medicine is sold as a solution and substance-liquid.

pharmachologic effect

Dimephosphon is an anti-acidic drug that improves SCR (acid-base state) with acidosis.

Pharmacodynamics and pharmacokinetics

In addition to the normalization of KHS with acidosis, this drug helps to enhance the reabsorption of bicarbonates, ventilation of the lungs, as well as the processes of acid and ammoniogenesis in the kidneys.
The drug has membrane-stabilizing, antioxidant and anti-inflammatory properties. It improves blood flow and metabolism in the brain tissues, promotes regulation of blood circulation, reduces cardiac and pulmonary insufficiency, strengthens the protective functions of the skin and mucous membranes.
The main anti-acid effect of the drug is due to the intensification of the pulmonary and renal mechanisms of regulation of the KHS. In addition, the effect is increased blood flow and tissue metabolism, as well as a decrease in the level of pyruvic and lactic acid in the brain tissues.
The drug helps to stabilize cell membranes, improves brain activity and helps normalize sleep. It also restores the reactivity of the brain vessels and reflexes, the arcs of which are closed through the stem divisions, reduces the severity of pyramidal, vestibular, auditory, cerebellar and visual disorders.
Antioxidant effect due to the fact that Dimephosphon prevents the activation of lipid peroxidation, as well as increases the activity of antioxidant enzymes in the brain tissues.
It also promotes the activation of energy processes by influencing mitochondria and stimulating the pituitary-thyroid system. Thus, tissues consume more thyroid hormones, and energy and catabolic processes in the mitochondria become more active.
It can be used for cerebrovascular insufficiency in various forms, as it improves microcirculation and increases the resistance of nerve cells to ischemia.
After one use, the drug easily penetrates through the histohematological barriers. The maximum concentration is achieved in 1 hour. The active substance is distributed to many organs and tissues.
The drug is excreted mainly with urine in an unchanged form.

Indications for the use of Dimephosphon

Indications for the use of Dimephosphon are as follows:
    subcompensated hypertension in a small circulatory system;
    acidosis in case of pneumonia, ARVI, diabetes, chronic lung diseases, and also after operations;
    transient ischemic attacks;
    diseases of ENT organs;
    ischemic and hemorrhagic stroke;
    myelopathy;
    radiculopathy;
    ITC;
    atopic dermatitis;
    dental diseases;
    rachitis-like diseases in childhood;
    Chronical bronchitis;
    trauma of the brain and spinal cord (neurosurgical operating rooms);
    bronchial asthma;
    Syndrome and Meniere's disease;
    Pollinosis in children;
    vegetative lability;
    hereditary entero-oxaluric syndrome;
    Infectious-inflammatory diseases of the skin and mucous membranes;
    trophic ulcers;
    mucositis in radiation therapy of malignant neoplasms;
    encephalopathy;
    infected skin lesions.

Contraindications

It is not recommended to use this drug with a tendency to allergic reactions. In addition, it is contraindicated in the following cases:
    chronic renal failure (I-II degree);
    epilepsy.
For children under 18 years of age, the drug is not given for TBI, circulatory disorders in the brain, osteochondrosis, chronic nonspecific lung diseases, migraine, planned neurosurgical operations, multiple sclerosis, the consequences of ischemic and hemorrhagic strokes, chronic cerebrovascular insufficiency (provoked by atherosclerosis and hypertension), Meniere's disease . Children under the age of 12 years of age are not eligible for medication in case of vegetative-vascular dystonia according to the parasympathetic type.

Side effects

The following adverse reactions are possible: nausea, heartburn, drowsiness, vomiting, diarrhea (if applied internally), impaired concentration. As a rule, all undesirable manifestations quickly pass and do not require special treatment.
If some irritation occurs during external application, it is desirable to reduce the concentration of the solution by a factor of 2.

Instructions for use Dimephosphon (Method and dosage)

The medication is administered intravenously 1-4 times a day, on an average of 30-50 mg / kg. Because of the bitter taste, you can drink milk, sweet tea or fruit juice. The scheme of therapy depending on the disease may be as follows:
    TBI - 3-8 weeks;
    disorders of cerebral circulation, Meniere's syndrome - 1-4 weeks;
    prevention of exacerbation of pollinosis - 3 weeks (before the expected onset of seasonal deterioration and during flowering of the plant causing allergies);
    Neurosurgical operations - for five days before surgery and approximately 10-14 days after;
    vegetative dysfunction, acidosis, diseases of the respiratory system, as well as atopic bronchial asthma (in childhood) - 2-4 weeks.
Instructions for use Dimephosphon outwardly informs that the medicine is used in the form of lotions, dressings and turundas with a solution. In the case of infectious inflammatory allergic reactions on the skin and mucous membranes, the procedures are done every day for 3-14 days. During the complex treatment of acne, the affected areas of skin should be wiped with a solution in the afternoon 3-4 times, and in the evening, make lotions. In erysipelas, the affected area is lubricated 3 times every day for 3-5 days. And in order to prevent radial mucositis 20 minutes prior to exposure to the dose, gauze napkins with a solution fit into the projection of radiation beams.
Intravenously, the drug can be used in a jet or drip. Instructions for the use of Dimephosphon inkjet provide the following scheme: 1-2 ampoules of the drug diluted in about 15 ml of pure water for injection, or 15 ml of a solution of 0.9% sodium chloride. For the use of drip, the drug is diluted in 200-400 ml of a 0.9% sodium chloride solution. Dimephosphon should be administered 1-4 daily for 7-10 days.

Overdose

In case of drug overdose, the degree of severity of dose-dependent adverse reactions is increased. As a therapy prescribed gastric lavage, as well as the reception of activated carbon. Treatment is symptomatic.

Interaction

Significant drug interaction with other agents has not been established.

Terms of sale

You don't need a prescription to buy Dimephosphon online.

Storage conditions

Store this medication at room temperature in a dark place.

Shelf life

Do not use the drug after the expiration date indicated on the package. The maximum shelf life is 3 years.

Reviews about Dimephosphon

Reviews about Dimephosphon on the forums are mostly good. Patients note the efficacy and mild effect of this drug, without severe adverse reactions. Positive reviews leave and those who gave the drug to children.
Among the negative moments, note only the bitter taste of the drug. However, it can be diluted in a liquid, so this minus is considered insignificant.