Dramina tabs 50mg #10

Dramina user manual

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Composition

In one tablet of Dramina contains the active component: dimenhydrinate - 50 mg.
Additional ingredients: magnesium stearate, lactose monohydrate, MCC, povidone and crospovidone.

Form of issue

Dramina is released in the form of tablets of 50 mg, packed in a pack of 5 or 10 pieces.

pharmachologic effect

Tablets have sedative, antiemetic, antihistamine and anti-allergic effect.

Pharmacodynamics and pharmacokinetics

For this preparation blocking of central H1-histamine receptors and m-holinoblockers is characteristic. In addition, the synthesis of acetylcholine is blocked, the production of acetylcholine is reduced at the level of presynaptic endings, and the release of the substance into the synaptic cleft is reduced. Also, oppression of vestibular stimulation by summing the antihistamine and m-holinoblocking effect was noted.
High dosages of the drug can affect the semicircular canals in the middle ear area, which are responsible for maintaining equilibrium and orientation in space. Dramina positively affects the vestibular apparatus, relieving of dizziness, nausea and vomiting, which cause various vestibular disorders, for example, kinetosis.
Tablets have a sedative, moderate anti-allergic and mildly local anesthetic effect. Getting inside the body, the medicine is quickly and fully absorbed from the digestive tract. The manifestation of an antiemetic effect is noted 15-30 minutes after taking the drug and lasts an average of 3-6 hours. As for the distribution of matter, it occurs in the tissues of the body, with easy binding to plasma proteins. High concentrations of Drumina can penetrate through blood-brain or hematoplacental barriers. Metabolism and excretion occurs within 24 hours, an insignificant part of the substance can excrete with breast milk.
Long-term use of the drug sometimes causes tolerance to dimenhydrinate, which helps to reduce the severity of antiemetic and sedative effect, but completely retaining antihistamine action.

Indications for use

The preparation is intended for:
    prevention and treatment of kinetosis, sea and air sickness, symptoms of vestibular disorders and hyperstimulation of the labyrinth, for example, dizziness, nausea, vomiting, and so on;
    therapy of vestibular disorders associated with craniocerebral trauma;
    treatment of Ménière's disease.

Contraindications for use

It is not recommended to take Dramina when:
    increased individual sensitivity to its components;
    epilepsy;
    convulsive syndrome;
    acute exudative and vesicular dermatoses;
    age of patients up to a year;
    lactation, pregnancy.
It is necessary to take into account the peculiarities during treatment of patients with closed-angle glaucoma, bronchial asthma, prostatic hyperplasia, cardiovascular disorders, hyperthyroidism, gastrointestinal ulcers and so on.

Dramina during pregnancy

During lactation and pregnancy, this medication is not recommended.
If there is a need for prescription of tablets during lactation, then during the treatment, breastfeeding ceases. At the same time, you can resume feeding of the baby 5-7 days after the last taking of the drug.

Side effects

When treating Dramina tablets, there may be disturbances in the activity of the central nervous system, for example: general weakness, fatigue, decreased reaction rate, impaired concentration, development of headache, dizziness, nervousness, anxiety, sleep or wakefulness problems, and more.
Also, deviations in the activity of the digestive organs, respiratory, cardiovascular system, the development of allergic reactions and other undesirable symptoms are possible.
In some cases, the side effects can be reduced or eliminated by stopping treatment or reducing the therapeutic dosage. It is recommended that all cases of adverse symptoms be discussed with the attending physician.

Instructions for use Dramina (Method and dosage)

As you know, Dramina tablets instructions for use advise to take in, before eating. They are used in the treatment of sea and air sickness, during the prevention and treatment of vestibular or labyrinthine disorders, for example, dizziness, nausea or vomiting, with the exception of the abnormalities that antitumor therapy is causing.
Dramina for children 3-6 years is prescribed in the form of half or a quarter of the pill to take a day 2-3 times. Children of 7-12 years are prescribed half or a whole tablet a day 2-3 times. For children from 12 years and adults, patients can appoint 1-2 times a day 2-3 times.
Treatment of Meniere's disease in children under 12 years requires the appointment of a daily dose of half or one tablet 2-3 times, for patients 12 years old it is fashionable to take 1-2 tablets 2-3 times.
The maximum daily dosage for adult patients should not be more than 7 tablets.
When carrying out prophylaxis of kinetosis it is recommended to take the medicine for half an hour before the trip on 1-2 pieces.
Duration of drug use and repetition of the therapeutic course should be carried out in agreement with a specialist.

Overdose

In cases of overdose, the occurrence of dryness of the mucous membranes of the oral cavity and nasopharynx, problems with breathing, confusion, the development of convulsions and hallucinations may occur.
The development of symptoms of overdose requires the provision of medical care with washing the stomach, the appointment of salt laxatives, the conduct of symptomatic therapy.

Interaction

Dramina can enhance the effect of m-holinoblokatorov, for example, atropine, as well as tricyclic antidepressants, barbiturates, catecholamines, neuroleptics, hypnotics and sedatives. Simultaneous use with drugs that depress the central nervous system, increases the effectiveness of Drumina. There was also a decrease in the depressive effect of acetylcholine in the area of ​​the heart muscle. Combination therapy with bismuth preparations, psychotropic and analgesic agents, scopolamine increases the risk of developing a deviation of the visual function. In addition, the incompatibility of Dramina with ototoxic antibiotics, for example, streptomycin, amikacin, neomycin, viomycin and kanamycin, has been established. It is possible to mask the symptoms of ototoxicity of these drugs, the development of hearing impairments, which prevents timely diagnosis.

Terms of sale

You can buy Dramina without a prescription.

Storage conditions

To store the drug is intended a place with a temperature of up to 25 C, reliably protected from children.
Shelf life - 5 years.

Alcohol

Simultaneous use of Drumina and alcohol can significantly enhance its effect.

Reviews about Dramina

As shown by numerous reviews about the drug, all who took it in this or that case, note its high efficiency. Often, users discuss on the network, from which the Dramina tablets help best and causes drowsiness.
Some patients report that the effect of this remedy manifests itself in half an hour and at about the same time they feel very sleepy. However, others notice a positive effect, but did not feel side effects, including drowsiness. Therefore, it can be understood that the sedative effect depends precisely on the characteristics of the nervous system of a particular person.
In addition, the topic of the effect of the drug on young children is actively discussed. At the same time, when the tablets are used in an airplane, the responses about Dramina report that patients better tolerate flights. For this reason, if the child has a propensity for complications of well-being during the trip, then you need to choose the right medicine together with the pediatrician, which will help make the trips more enjoyable.