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Vinpotropile tabs 10mg + 800mg #60

  • $24.99
  • 3 or more $24.40
  • Availability:In Stock

Vinpotropile instructionReed more and buy Vinpotropile on this pageCompositionIn 1 ml concentrate for the preparation of the infusion solution is 1 mg vinpocetine, 80 mg pyracetam and inactive compounds: ascorbic (5 mg) and succin..

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Vinpotropile instruction

Reed more and buy Vinpotropile on this page


In 1 ml concentrate for the preparation of the infusion solution is 1 mg vinpocetine, 80 mg pyracetam and inactive compounds: ascorbic (5 mg) and succinic acid (13.4 mg) sodium disulfite (3 mg) and distilled water for injections (not more than 1 ml ).
In one film-coated tablet, 10 mg vinpocetine, 800 mg piracetam, and calcium hydroxide dihydrate (120 mg), povidone (21 mg), sodium croscarmellose (33 mg), magnesium stearate (7 mg), talc (7 mg), microcrystalline cellulose (102 mg). The film shell includes Opadry II (35 mg) brown, macrogol, lactose monohydrate, as well as dyes: iron oxide red, iron oxide black and titanium dioxide.
In one capsule - 5 mg vinpocetine, 400 mg piracetam, lactose and talc as auxiliary substances. The hard gelatin capsule consists of two parts - the body (gelatin, titanium dioxide and dyes - quinoline yellow and "Sunset Sunset") and caps (gelatin, titanium dioxide and dye azorubin).

Form of issue

Vinpotropile is available in three dosage forms:
    In oval-shaped tablets that have a risk and are coated with a filmy coating of beige color with a grayish color. In the cross section, the color is almost white. Packed tablets in blisters, calculated on 10 pieces, in a cardboard bundle can be 3, 6 blisters.
    In two-color capsules, the color of yellow and red (cap), containing a powder of white or beige color, which can include individual crystals and lumps. In a carton box there can be 2, 3, 5, 10 blisters for 10 caps. or 2, 4, 6, 8 blisters for 15 pcs., a polyethylene bottle for 15, 50 caps.
    In the form of a concentrate intended for the preparation of an infusion solution, which is a clear liquid. Usually is issued in ampoules for 5 ml, placed on the contour plastic pallet 5 or 10 ampoules, in the carton packing there are 1 or 2 of them. The drug can be equipped with a scarifier. Ampoules of brown color, made of glass of the first hydrolytic class, have a break point.

pharmachologic effect

Nootropic action and improvement of the blood flow of the brain.

Pharmacodynamics and pharmacokinetics

Vinpotropile is a combined preparation that can improve cerebral blood flow due to the active substance - vinpocetine and have a nootropic effect through the active ingredient - piracetam.
Vinpocetine is able to improve brain metabolism by increasing glucose and oxygen consumption, norepinephrine and serotonin metabolism, neuronal resistance to hypoxia, and has an antioxidant effect. Intensification of glucose transport occurs through the BBB, while the decay of glucose molecules becomes more energy-efficient: the Ca2 + -dependent PDE is selectively blocked by the aerobic pathway and the level of AMP, catecholamines, and cyclic GMP and ATP of the brain increases. Regarding the blood system - reduces the viscosity and aggregation of platelets, increases the plasticity of oxygen carriers - erythrocytes, blocks the utilization of adenosine and activates the return of oxygen. Enhanced cerebral blood flow does not cause significant changes in systemic circulation. It is established that the substance can penetrate through the placental and histohematological barriers.
Piracetam is included as an active substance in Vinpotropile to optimize the integrative activity of the brain: by promoting memory consolidation and the speed of spreading excitement, hemispheric coupling makes the learning process more effective. In addition, sedative and psychostimulating effect is not observed. Under the influence of drugs gradually improves microcirculation and suppressed aggregation of activated platelets, which has a cerebroprotective effect in hypoxia, intoxication, exposure to electric shock. The EEG shows that α- and β-activities are enhanced, δ-activity decreases, and the severity of the vestibular nystagmus is reduced. At the initial stage of cerebral vascular disease in the elderly and senile age has a pronounced effect. Penetrating through the GE and placental barriers, it is effectively removed by hemodialysis.

Pharmacokinetics of the concentrate (parenteral administration)

    Vinpocetine reaches a therapeutic plasma concentration of 10-20 ng / ml, with a volume distribution of 5.3 liters per kilogram, binds to proteins by 66 percent with a clearance of 66.7 l / h, has an extrahepatic metabolism. In breast milk within an hour is 0.25%, half-life is 220-367 min. Elimination by the kidneys and through the intestine (ratio 3: 2).
    The half-life of pyracetam from plasma is 4.5 hours, of the brain - 7.7 hours, of cerebrospinal fluid - 8.5 hours (with chronic and terminal renal failure may extend to 2.5 days). Virtually without biotransformation, two-thirds of the substance is excreted by the kidneys in 30 hours, with a total clearance of 80-90 ml. Studies in the vivariums showed that the substance is selectively cumulated in the tissues of the GM cortex, mostly basal cores, in the frontal lobes, parietal lobes, occipital lobes and in the cerebellum.

Pharmacokinetics of tablets and capsules

The maximum concentration of vinpocetine is reached after 2-4 hours, and the absorption process occurs mainly in the initial sections of the gastrointestinal tract. Subsequent inductions induce linear kinetics. The half-life is approximately 290 minutes. Whereas the bioavailability of piracetam is approximately 100%, the maximum concentration of 84 μg per ml after an hour, multiple-dose increases it to 115 μg per ml.

Indications for use Vinpotropile

Any of the dosage forms is prescribed for:
    insufficiency of cerebral circulation in the period of recovery after an ischemic or hemorrhagic stroke;
    parkinsonism of vascular genesis;
    various intoxications;
    psychoorganic syndrome, where the signs of adynamia and asthenia predominate.
The use of capsules and concentrate for the preparation of infusions is effective for encephalopathies of various genesis, as well as alcoholism, brain traumas and other CNS diseases, which are accompanied by a deterioration of intellectual and mnestic functions. In addition, with:
    asthenic syndrome and Ménière syndrome;
Additional indications for the use of tablets are:
    chronic circulatory insufficiency of the brain of hypertensive and post-traumatic origin;
    symptomatic treatment for dizziness;
    prevention of migraine and seasickness.


    hypersensitivity to constituents;
    severe cardiac arrhythmias;
    severe course of ischemic heart disease;
    acute phase of hemorrhagic stroke;
    renal and / or hepatic insufficiency;
    deficiency of the enzyme - lactase, established lactose intolerance;
    tablets are contraindicated for glucose-galactose malabsorption;
    pregnancy and breastfeeding;
    age category up to 18 years.

Precautions should be taken when:

    hemostasis disorders;
    heavy bleeding;
    benign hyperbilirubinemia, including those with Gilbert's syndrome;
    viral hepatitis and alcoholic liver damage;
    deficiency of the enzyme glucose-6-phosphate dehydrogenase (tablets and capsules);
    patients of advanced age.

Side effects

Regarding different organs and systems, the following reactions may occur:
    CCC: ECG changes in the form of depression of the ST segment, prolongation of the QT interval, the appearance of tachycardia, extrasystole, worsening of angina pectoris, functional mobility of blood pressure, hot flashes.
    CNS: sleep disorders, headache, dizziness, agitation, anxiety, irritability, decreased concentration and attention, depression, extrapyramidal disorders, hyperkinesis, convulsions, tremor.
    The digestive system: dry mouth, gastralgia, heartburn, nausea and vomiting, diarrhea.
    Sense organs: coordination disorders.
    Skin: redness and itching, hives or dermatitis.
    Other: increased libido and sexual activity, weight change in the direction of increase, general weakness, increased sweating.
As a result of Vinpotropile infusions, local reactions may occur, which manifest as pain at the site of injection and thrombophlebitis.

Instructions for use Vinpotropile (Method and dosage)

To prepare a solution for infusions, take 2-3 amp. of the preparation, 500 ml of a 0.9% solution of sodium chloride and a dextrose-containing solution. Enter should be intravenously at 50-100 ml once a day at a speed of not more than 80 drops per minute. Carry out infusion no later than three hours before bedtime. The standard course of treatment is from 10 days to 2 weeks, which, if necessary, can be repeated after 6-8 weeks. If there is a marked improvement, you can switch to another method of intake - inward.
Instructions for use Vinpotropile in tablets: take inside 1 tablet 2 or 3 times during the day, but no later than 4 hours before sleep, and does not matter the mode of food intake. You need to drink plenty of clean water.
Capsules are also taken orally, however, before meals, 1 table. 2 or 3 times during the day, but no later than 4 hours before bedtime. As maintenance therapy, you should take 1 capsule 3 times during the day.
The length of the course of treatment with tablets and capsules ranges from 2-3 weeks to 2 months and even half a year. The withdrawal of the drug requires a gradual dose reduction or the use of another dosage form, for example, capsules. Duration of treatment and dosage should be checked with your doctor.


An overdose of vinpocetine is accompanied by an increase in the severity of dose-dependent adverse reactions. For treatment, gastric lavage, activated charcoal and symptomatic therapy are prescribed.
Overdose of pyracetam invokes abdominal pain, diarrhea with blood. Treat symptomatically, hemodialysis in this case is effective at 50-60%. A specific antidote was not found.


    Heparinotherapy: increased risk of hemorrhagic complications.
    Increase in the action of thyroid hormones.
    Antipsychotic drugs (neuroleptics), psychostimulants, indirect anticoagulants - enhancement of effects.
    Acenocoumarol - reduced platelet aggregation, viscosity, fibrinogen content and von Willebrand factor.
    Methyldopa is the potentiation of the hypotensive effect.
    Anticonvulsants - a decrease in the effectiveness of drugs.
    Use with caution with substances that have a central or antiarrhythmic effect.
The infusion solution is pharmaceutically compatible with solutions such as: Dextrose (5, 10, 20% -cent), fructose (5, 10, 20%), 0.9% Sodium Chloride solution, Ringer's solution, Mannitol solution 20% and hydroxyethyl starch (6 , 10%).

Storage conditions

In a dry dark place, the temperature is not more than 25 ° Celsius.
List B. For the safety of children and animals it is recommended to store in an inaccessible place.
Shelf life - two years from the date of issue.

Reviews about Vinpotropile

Reviews of Vinpotropile Buyers confirm its effectiveness as a nootropic drug that can improve the circulation of blood in the brain. They say that the state and general feeling, as well as attention and memory, improve noticeably and argue that the drug is worth its money.
The doctors' comments about Vinpotropile are positive, it is used in psycho-geriatric practice, it is prescribed for various conditions (for example, intoxications), insufficient blood circulation of the brain, as well as for the prevention of migraine and seasickness.

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