Afrin Extro spray 0.05% 15ml

Afrin Extro instruction for use

You can buy Afrin Extro spray on this page

Nasal Spray Afrin Extro-anticongestive, alpha-adrenomimetic drug.
Alpha-adrenostimulating agent for topical application. Has vasoconstrictive effect. Oxymetazoline causes narrowing of the vessels of the mucous membranes of the nose, paranasal sinus and eustachian tube, which leads to a decrease in their edema and the release of nasal breathing in allergic and / or infectious inflammatory rhinitis (runny nose).
Due to the presence of auxiliary substances in the medicinal product (MCC, carmellose sodium and povidone K29-32), Afrin exstra nasal spray does not flow out of the nose and does not drain into the throat, tk. after injection into the nasal passages, the spray becomes more viscous and retained on the mucous membranes of the nose more effectively than the standard aqueous solution.
On the basis of published clinical studies, the intranasal administration of an aromatic composition similar to that of a medicament containing levomenthol (also known as menthol), cineole (also known as eucalyptus) and camphor, causes a temporary sensation of cooling the nasal mucosa due to interaction with the cold trigeminal receptors nerve on the surface of the mucous membrane.
According to clinical studies, the drug begins to act for 1 minute, and the effect lasts up to 12 hours.

Pharmacokinetics

When used as a nasal spray, oxymetazoline is practically not detected in the blood plasma.

Indications for use

Indications for the use of the spray Afrin Extro are: symptomatic therapy of rhinitis (rhinitis) of allergic and / or infectious inflammatory etiology; sinusitis; eustachiitis; hay fever.

Mode of application

Before each use of the spray, Afrin Extro, it is necessary to vigorously shake the bottle. Before the first application of the nasal spray, it is necessary to calibrate it by pressing the spray head several times.
Adults and children over 6 years of age - 2-3 injections into each nasal passage with an interval of 10-12 hours. Multiplicity of application can be increased up to 3 times a day in adults. Do not exceed the specified dose.

Side effects

In general, the drug Afrin Extro is well tolerated, and possible adverse events are usually mild and transient.
Transient dryness and burning of the mucous membrane of the nasal cavity, dry mouth and throat, sneezing; increased blood pressure, increased anxiety, nausea, dizziness, headache, insomnia, palpitations, sleep disturbances. With prolonged use - tachyphylaxis, reactive hyperemia and atrophy of the mucous membrane of the nasal cavity. Benzalkonium chloride, which is part of the drug, can cause local skin reactions.

Contraindications for Afrin Extro

Contraindications to the use of the spray Afrin Extro are: hypersensitivity to sympathomimetic drugs, to any component of the drug; atrophic rhinitis; simultaneous use of MAO inhibitors (including the period of 14 days after their cancellation); children's age till 6 years.
With caution: coronary artery disease; arrhythmias; chronic heart failure; severe atherosclerosis; arterial hypertension; hyperthyroidism; diabetes; chronic renal failure; angle-closure glaucoma; hyperplasia of the prostate with clinical symptoms; pregnancy; lactation period.

Pregnancy

The safety of the drug Afrin Extro in pregnant women and during lactation is not established, so the drug should be prescribed to pregnant or lactating breast only on the advice of a doctor if the expected benefit of using the drug for the mother exceeds the potential risk to the fetus or baby.

Interaction with other drugs

Afrin Ekstro slows the absorption of local anesthetic drugs, lengthens the time of their action.
Joint use with other vasoconstrictive drugs increases the risk of side effects.
With the simultaneous use of MAO inhibitors (including the period of 14 days after their withdrawal), maprotiline and tricyclic antidepressants - an increase in blood pressure.

Overdose

Symptoms of an overdose of the spray Afrin Extro: with a significant overdose or accidental ingestion, nausea, vomiting, cyanosis, fever, tachycardia, arrhythmia, increased blood pressure, dyspnea, mental disorders, depression of the central nervous system (drowsiness, lower body temperature, bradycardia, lowering blood pressure, stopping breathing and coma).
Treatment: symptomatic; with accidental ingestion - gastric lavage, activated charcoal. Vasopressor drugs are contraindicated.

Storage conditions

At a temperature of no higher than 25 ° C.
Keep out of the reach of children.

Form of issue

Afrin Extro-nasal spray, 0.05%.
In a hermetically sealed plastic opaque bottle with a capacity of 23 ml with a fine atomizing dispenser and a protective cap covered with shrink film to control the first opening with the company logo, 15 ml.

Composition

Spray nasal Afrin Extro - 1 ml contains the active substance: oxymetazoline hydrochloride 0.5 mg.
Excipients: MCC and carmellose sodium (avicel RC 591) - 30 mg; sodium hydrophosphate - 0.975 mg; sodium dihydrogen phosphate monohydrate - 5,525 mg; disodium edetate dihydrate 0.3 mg; macrogol 1450 - 50 mg; Povidone K29-32 - 30 mg; benzyl alcohol - 3 mg; cineol - 0.2 mg; camphor - 0.2 mg; levomentol 0.6 mg; benzalkonium chloride a solution of 17% - 1.471 mg; polypropylene glycol - 5 mg; purified water - q.s. up to 1 ml.

Additionally

With prolonged use (more than 1 week), it is possible to resume symptoms of nasal congestion. If you need to continue treatment for more than 5 days, you need to consult a doctor.
Avoid contact with the eye.
Influence on the ability to drive vehicles and work with machinery. The drug, if used correctly and at recommended doses, does not affect the driving of vehicles and work with mechanisms, however, if such side effects, such as dizziness, arise, one should refrain from these activities.

Terms of sell

You can buy spray Afrin Extro without doctor's prescription.