Polydexa with Phenylephrine spray 15ml

Polydexa with Phenylephrine instruction

You can buy Polydexa with Phenylephrine here

Composition

Nasal spray is composed of neomycin sulfate, Polymyxin b sulfate, dexamethasone sodium metasulphobenzoate, phenylephrine hydrochloride. In addition, the drug contains additional substances: lithium chloride, methyl parahydroxybenzoate, citric acid, macrogol 400, lithium hydroxide, Polysorbate, water.

Form release

The drug is available in the form of a spray. It is a colorless transparent liquid, which is contained in a bottle of polyethylene with a sprayer. The bottle contains 15 ml of the drug, it is Packed in a pack of cardboard.

Pharmacological action

A combination drug that is used in otorhinolaryngology for topical use. Polydexa with Phenylephrine has an anti-inflammatory effect due to the action of dexamethasone on the nasal mucosa. Phenylephrine has a vasoconstrictor effect, and antibiotics neomycin and polymyxin B cause antibacterial effect. The combination of antibiotics allows to expand the range of their action. Therefore, these drops in the nose with an antibiotic act on most gram-positive and gram-negative organisms that provoke the development of infectious and inflammatory diseases of the nasal cavity and sinuses.

Pharmacodynamics and pharmacokinetics

There is no data on pharmacokinetics of the drug due to its low systemic absorption.

Indications for use

Nasal drops (spray) Polydexa with Phenylephrine should be used for the treatment of infectious and inflammatory diseases of the nasal cavity, sinuses and nasopharynx:
acute and chronic purulent rhinitis;
sinusitis, sinusitis, sinusitis;
acute and chronic rhinopharyngitis;
chronic adenoiditis;
purulent rhinitis in children, as a consequence of prolonged intubation by nasotracheal method;
prevention and treatment after surgery on the nasal cavity and sinuses.

Contraindications

Polydexa spray is not used for the nose in the following diseases and conditions:
high sensitivity to medium components;
suspicion for the development of angle-closure glaucoma;
the use of MAO inhibitors;
kidney disease, in which there is albuminuria.
Caution should be used in the presence of drug patient signs of hyperthyroidism, hypertension, angina, coronary heart disease.

Side effect

Perhaps the manifestation of the following side effects when taking the drug. Polydexa with Phenylephrine for the nose in some cases can provoke a feeling of dryness in the nose, as well as the manifestation of allergic reactions – itching, skin rashes, hives. The medicine for the nose causes systemic adverse effects only if it is used for a long time for treatment, or if it is used in a dose that is significantly higher than the recommended one. As a systemic side effects may manifest headache, tremor, tachycardia, pallor of the skin, increased blood pressure, insomnia.

Instructions for use (Method and dosage)

If you use nose drops Of Polydexa with Phenylephrine, the instruction must be taken into account. Adult patients should apply a spray to the nose in the following way: from 3 to 5 times a day, one injection is carried out in each nasal passage.
Instructions for the use of nasal spray for children from 12 years provides no more than 3 injections per day in each nasal passage.
Treatment lasts from 5 to 10 days. To make the injection, you need to click on the bottle. It should be kept upright, and the head should be tilted slightly forward so that the solution gets into the nasal passage in the form of a spray, not as a liquid stream. Only one injection press is carried out.
If no improvement is observed within 10 days, you should consult a doctor and stop treatment with the drug.
You can not use the drug for the purpose of washing the sinuses of the nasal cavity. Polydexa with Phenylephrine in sinusitis is a drug of choice, experts note that it should be used strictly according to the instructions. Reviews for sinusitis indicate that the effect of the use of the drug depends on the individual characteristics of the body.

Overdose

The local application overdosing is impossible, because the absorbability of the substances, when applied topically is very low.

Interaction

Nasal spray for children and adults Polydexa with Phenylephrine is often used in combination treatment due to good compatibility with other drugs. However, with some drugs Polydexa with Phenylephrine is not combined.
When combined with Bromocriptine increases the risk of arterial hypertension.
When combined with Guanethidine, the hypertensive effect of Phenylephrine increases.
When combined with MAO inhibitors in patients with hypertension increases the risk of hypertensive crisis.
Do not combine taking the drug and treatment with selective MAO inhibitors due to the lack of accurate information about such interaction.
When using Galotan or Cyclopropane in conjunction with Polydexa increases the risk of ventricular fibrillation.
Possible negative effects on cardiac function when combining the drug with Bepridil, Halofantrine, Sparfloxacin, Aminoglutetimid, Terfenadine, Sultopridom, Erythromycin, Winkaminom, Astemizole, Pentamidine.
In addition, caution should be exercised when taking the drug for a long time with Acetylsalicylic acid, other salicylates, as well as with antiarrhythmic drugs.
Special caution is necessary when combining Polydexa with weakened live vaccines, as there is a high probability of generalization of the disease.

Terms of sale

You can buy Polydexa with Phenylephrine without a prescription.

Storage conditions

Refers to the list B. it is Necessary to store the drug at a temperature not exceeding 25°C, protect from access to children.
Shelf life - 3 years.

Special instruction

Polydexa with Phenylephrine the drug cannot be taken orally. Do not practice treatment means longer than 10 days, as there is a risk of withdrawal syndrome and iatrogenic rhinitis. With prolonged therapy or in the use of high doses of the drug, it can have a systemic effect on the body.
Due to the presence in the composition of Polidexa corticosteroid can be changed for allergies, but local symptoms persist.
The drug contains dexamethasone, which in the process of doping control can give a positive result.
After the bottle of medicine is opened, you receive the possibility of contamination by microorganisms.
Cases impact on the ability to drive vehicles and work with the exact mechanisms are not mentioned.

What's better: Polydexa with Phenylephrine or Isofra?

Isofra or Polydexa with Phenylephrine for children and adults is optimal, in each case, can only say a specialist. In the composition of the drug Izofra — framizetin sulfate, an antibiotic that belongs to the same group as the antibiotic from the composition of Polydoxy. To accurately determine the effectiveness of both drugs, it is necessary to conduct a bakposev to obtain information about the sensitivity of microorganisms to each of the antibiotics.

Children

Polydexa with Phenylephrine used in the treatment of children from runny nose, sinusitis, sinusitis. However, the instructions say that the drug can be used in the treatment of children only 12 years of age.
Treatment of young children is possible only under the strict supervision of a specialist and with careful observance of all recommendations for use.

Pregnancy and lactation

To date, there is no reliable research on the impact of Polydexa with Phenylephrine on the body of a pregnant woman and fetus. There is evidence that prolonged use of the drug may have an ototoxic effect on the fetus, which may eventually provoke incorrect formation of the hearing.
The drug is prescribed in some cases during pregnancy only after careful weighing of the expected benefits and harmful effects. If possible, the doctor prescribes other drugs for treatment.
During lactation during treatment with Polidexa breast-feeding should be discontinued.

With antibiotics

Nasal spray cannot be used in conjunction with the antibiotics Gentamicin, Streptomycin, Netilmicin, Amikacin, Monomitsin, probably because the increased ototoxic action.

Feedback about the Polydexa with Phenylephrine

Feedback about nazalnam spray Polydexa with Phenylephrine testify to its effectiveness as a tool is a new generation product. It is noted that nose spray often improves the condition of the patient after several uses.
There are reviews for nose drops, where it is that the drug helped reduce the intensity of pain in the maxillary sinuses, headaches, swelling. However, it is noted that when using the tool, you need to follow the instructions accurately and use it only as recommended by the doctor. In the reviews there are negative comments about the inconvenience of using the bottle.