Rinzasip powder 5gr #10

Instruction for Rinzasip

You can buy Rinzasip here

Composition

In the composition of the drug: 750 mg of paracetamol, 20 mg of maleate of phenylamine, 30 mg of caffeine, 10 mg of phenylephrine hydrochloride. Also, the preparation contains auxiliary elements: citric acid, sodium citrate, sanset yellow dye FCF, orange flavor additive, saccharin sodium, sucrose.

Form of issue

The medicine is produced in a sachet of 5 grams. In each sachet is a finely dispersed orange powder, white impregnations are possible. The suspension prepared from it has a taste of orange, black currant or lemon.
Sasha is sold in packs of cardboard, 5, 10, 25, 50 or 100 in each.

pharmachologic effect

Anesthetic, vasoconstrictive, antipyretic.

Pharmacodynamics and pharmacokinetics

Pharmacological activity of the drug is determined by the totality of its constituent substances.
Paracetamol - an analgesic, antipyretic, belongs to the group of anilides. Reduces temperature, anesthetizes. Has a weak anti-inflammatory activity. Compared with other substances in this group, paracetamol is a low-toxic substance. The compound inhibits the synthesis of prostaglandins by blocking both forms of the cyclooxygenase enzyme. Also, the agent selectively blocks COX3 (central nervous system) without affecting COX1 and COX2, which are located at the periphery.
Paracetamol does not have a negative effect on the gastrointestinal tract, does not cause delay of Na + ions in the body, violations of the water-salt balance. The substance penetrates through the blood-brain, placental barrier, absorbed in the small intestine. The degree of connection with blood plasma proteins is high enough, the maximum concentration is observed in half an hour - hour after ingestion.
Chlorpheniramine - a potent antihistamine, blocks H1 histamine receptors. The substance reduces the degree of permeability of capillaries, relieves spasm in the bronchi, has anti-edematous activity. This weak sedative, has the property to reduce the intensity of mucus production in the nasopharynx and bronchi.
Caffeine simulates the central nervous system, improves performance, both mental and physical. In combination with paracetamol accelerates absorption and enhances the effectiveness of the latter.
Phenylephrine hydrochloride is an alpha-adrenomimetic. The substance narrows the blood vessels, raises blood pressure, removes the swelling of the mucous membranes, lowers the pressure in the middle ear and sinuses of the nose. If the substance is used often and for a long time, then the body develops tolerance to phenylephrine, it requires an increase in dosage.

Indications for use

The drug is prescribed for symptomatic treatment of acute respiratory disease, influenza, ARVI and other colds.

Contraindications

The medicine is not prescribed:
    during pregnancy and lactation;
    children under 15;
    at reception, any of components of a preparation separately;
    when allergic to the substances that make up the product.
Care should be taken:
    atherosclerosis;
    with elevated blood pressure;
    patients with diabetes mellitus;
    in the presence of blood diseases;
    liver or kidney disease;
    hyperplasia of the prostate;
    with bronchial asthma;
    at a thyrotoxicosis.

Side effects

Possible:
    sleep disorders, mydriasis, dizziness, hyperexcitability;
    tachycardia and increased blood pressure;
    pain in the stomach, dryness of the mucous membranes, nausea, impaired liver function;
    disturbances in the work of the kidneys, inconvenient urination;
    urticaria, pruritus, rash, bronchial obstruction syndrome.

Instructions for use of Rinzasip (method and dosage)

Powder from one sachet is dissolved in a large amount of hot water, you can add honey or sugar to taste.
Powder Rinzasip instructions for use advise to apply this: the daily dosage is up to 4 packets. The drug is taken every 4-6 hours after eating. Duration of reception means - no more than 5 days.

Overdose

Overdose occurs mainly through paracetamol, which is part of the drug. When you take more than 15 grams of the substance, paleness of the skin, nausea, decreased appetite, vomiting. As therapy, gastric lavage, reception of enterosorbents, elimination of unpleasant symptoms, 8 hours after an overdose should be taken methionine, after 12 - N-acetylcysteine.

Interaction

When combined with the drug, the action of ethanol, sedatives and MAO inhibitors is enhanced.
The likelihood of adverse reactions from the drug is enhanced when combined with antidepressants, neuroleptics, phenothiazine derivatives, GCS, anti-Parkinsonics.
The effectiveness of diuretics taken concomitantly with paracetamol is significantly reduced.
When combined with guanetidine, the hypotensive effect of the drug is reduced, and the alpha-adrenostimulating effect of Rinzasip is enhanced.
It is not recommended to combine the drug with barbiturates, carbamazepine, inducers of microsomal liver enzymes, diphenine due to increased liver load.

Terms of sale

You can buy Rinzasip without prescription.

Storage conditions

Sasha should be stored in closed form, in a dry place, at a temperature of no higher than 30 degrees.
Shelf life - 3 years.

special instructions

If after 5 days after the beginning of the reception of the remedy in the state of improvement did not occur, you should seek help from a specialist.
In connection with the likelihood of drowsiness and weakness, you should refrain from controlling the mechanisms, driving vehicles during the drug.

In pregnancy and lactation

Due to the high toxicity and ability of the drug to overcome the blood-brain and placental barrier, its use during pregnancy during lactation is contraindicated.

Reviews about Rinzasip

On the forums there are many positive reviews about Rinzasip. The drug is effective and is relatively inexpensive. Adverse reactions occur rarely, helps quickly to get on their feet. However, do not forget that Rinzasip only eliminates the symptoms of the disease. Before you start taking it is recommended to consult a doctor.