Stopgripan powder #10

Stopgripan user manual

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Form of release, composition and packaging

Powder for the preparation of solution for ingestion (blackcurrant) is crystalline, from light pink to dark pink with blue crystals, with a characteristic smell of black currant; the prepared solution is opaque, purple, with the smell of black currant.
1 sachet
paracetamol 325 mg
phenylephrine hydrochloride 10 mg
Pheniramine maleate 20 mg
ascorbic acid 50 mg
Excipients: calcium phosphate, citric acid, maltodextrin, sodium citrate dihydrate, sucrose, titanium dioxide, ethyl maltol, malic acid, blackberry flavor, dye, brilliant blue, dye sunset yellow, dye Ponso 4R.
21.5 g - sachets (10) - packs of cardboard.

pharmachologic effect

Combined drug. Paracetamol has antipyretic and analgesic effect. Phenylephrine is a vasoconstrictive action, thereby contributing to the elimination of the edema of the nasal mucous membranes, nasopharynx and paranasal sinuses, to a decrease in discharge from the nose, thereby facilitating nasal breathing. Pheniramine has anti-allergic and anti-edematous effect, reduces vascular permeability, nasal discharge, lacrimation, eliminates sneezing. Ascorbic acid participates in the regulation of oxidation-reduction processes, carbohydrate metabolism, blood coagulability, tissue regeneration, in the synthesis of steroid hormones; increases the body's resistance to infections, reduces vascular permeability, reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid. It improves paracetamol tolerance and lengthens its action.

Indications for Stopgripan

- Catarrhal diseases, flu, acute rhinitis, rhinopharyngitis, sinusitis, inflammation of the paranasal sinuses, accompanied by fever, chills, runny nose, nasal congestion, headache;
- pain syndrome (mild and moderate): arthralgia, myalgia, neuralgia, migraine, dental and headache, pain with trauma, algodismenorea.

Contraindications

- hypersensitivity to paracetamol and other components that make up Stopgripan;
- taking other drugs containing substances that are part of Stopgripan;
- simultaneous reception of tricyclic antidepressants, MAO inhibitors, beta-blockers;
- portal hypertension;
- Alcoholism;
- diabetes;
- Pregnancy,
- lactation period;
- Children under 12 years old.
With caution in the expressed atherosclerosis of the coronary arteries, arterial hypertension, deficiency of glucose-6-phosphate dehydrogenase; blood diseases, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor syndrome), hepatic and / or renal insufficiency, eukrytougolnoy glaucoma, prostate adenoma; hyperthyroidism, pheochromocytoma, bronchial asthma.

Dosage

Contents 1 sachet (sachet) pour into a glass, pour hot water, stir until completely dissolved and drink. Adults and children over 12 years should take 1 packet 3-4 times / day with intervals between meals 6 hours (no more than 4 bags per day).
Consult your doctor if symptoms persist for 5 days.

Side effects of Stopgripan

In therapeutic doses, Stopgripan is usually well tolerated, but there may be an increase in blood pressure, allergic reactions (skin itch, rash, hives, angioedema), dry mouth, nausea, vomiting, epigastric pain, decreased speed of psychomotor reactions, increased excitability, dizziness , palpitations, sleep disturbances, urinary retention, renal colic, glucosuria, mydriasis, paresis of accommodation, increased intraocular pressure.
Given the presence of paracetamol in Stopgripan, rarely can there be violations of the hematopoiesis system (thrombocytopenia, leukopenia, agranulocytosis, hemolytic anemia, aplastic anemia); with prolonged admission in high doses, there may be abnormalities on the part of the liver and kidneys (hepatotoxic action, nephrotoxicity - papillary necrosis).

Overdose

It is conditioned, as a rule, by paracetamol. Possible: pallor of the skin, anorexia, nausea, vomiting, pain in the epigastric region; in severe cases - hepatic insufficiency, hepatonecrosis, increased activity of hepatic transaminases, increased prothrombin time, encephalopathy and coma. A detailed clinical picture of liver damage manifests itself after 1-6 days. Rarely, liver failure develops at a lightning speed and can be complicated by renal insufficiency (tubular necrosis).
Treatment: gastric lavage followed by the administration of activated charcoal; symptomatic therapy; introduction of donors SH-grypp and precursors of the synthesis of glutathione-methionine 8-9 hours after an overdose and N-acetylcysteine ​​- after 12 hours.

Drug Interactions

Strengthens the effects of MAO inhibitors, sedatives, ethanol.
Antidepressants, antiparkinsonics, antipsychotics, phenothiazine derivatives increase the risk of urinary retention, dry mouth, constipation.
Glucocorticosteroids increase the risk of increased intraocular pressure.
Paracetamol reduces the effectiveness of uricosuric drugs and improves the effectiveness of indirect anticoagulants.
Phenyramin simultaneously with MAO inhibitors, furazolidone can lead to hypertensive crisis, agitation, hyperpyrexia.
Tricyclic antidepressants enhance the sympathomimetic effect, the simultaneous administration of halothane increases the risk of ventricular arrhythmia.
Reduces the hypotensive effect of guanethidine, which in turn increases the alpha-adrenostimulating activity of phenylephrine.
With the simultaneous appointment of Stopgripan with barbiturates, diphenine, carbamazepine, rifampicin and other inducers of microsomal liver enzymes, the risk of hepatotoxic action of paracetamol increases.

special instructions for Stopgripan

To avoid toxic damage to the liver, Stopgripan should not be combined with the use of alcoholic beverages.
If, despite the reception of Stopgripan, the disease is accompanied by an ongoing fever or there are repeated increases in temperature, it is necessary to consult a doctor.
Impact on the ability to drive vehicles and manage mechanisms
Patients taking Stopgripan should refrain from occupations that require increased attention and speed of mental and motor reactions, including. and from driving a car.

Pregnancy and lactemia

Contraindicated in pregnancy and lactation.

Application in childhood

Contraindication: children under 12 years.

In case of violations of kidney function

Careful - with kidney failure.

With violations of liver function

Careful - with hepatic insufficiency.

Conditions of leave from pharmacies

To buy Stopgripan you don't need a prescription.

Terms and conditions of storage

Keep out of the reach of children, dry place at a temperature of no higher than 25 ° C. Shelf life - 2 years. Do not use after the expiry date specified by the packaging.