Coldrex Hotrem powder #10

Coldrex Hotrem instruction

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Composition

Coldrex Hotrem includes the following active components:
    paracetamol;
    ascorbic acid;
    phenylephrine hydrochloride.
Additional substances: citric acid, sucrose, sodium cyclamate, sodium citrate, corn starch, sodium saccharin, caramel SCS (E150), as well as lemon, honey or currant flavor.

Form of issue

Powder, which is contained in sachets, designed for 5 or 10 g.

pharmachologic effect

Powder Coldrex Hotrem is used for colds.

Pharmacodynamics and pharmacokinetics

The drug has a sympathomimetic, antipyretic, immunostimulating and analgesic effect. The features of its action depend on the properties of the components that make up the composition.
Active components are excreted mainly with urine. In addition, some ascorbic acid may be secreted with bile. The half-life of phenylephrine is 2-3 hours, and paracetamol is 1-4 hours.

Indications for use

The medicine is used to get rid of the symptoms of acute respiratory viral infection and influenza: hyperthermia, chills, sore throat and nose, headache, nasal congestion, painful sensations in the joints and muscles.

Contraindications

Powder is contraindicated for use with a negative reaction to its components, diseases of the circulatory system, thyrotoxicosis, lack of glucose-6-phosphate dehydrogenase, liver and kidney dysfunction, hypertension.

Side effects

When used according to the instructions, the medicine is well tolerated without side effects. In rare cases, the following negative reactions are noted:
    system of digestion and liver: increased activity of liver enzymes, vomiting, nausea, diarrhea, anorexia, dry mouth;
    nervous system: headache, insomnia, irritability, tinnitus, dizziness, tremor;
    allergy: skin itching, rash, angioedema, urticaria, Lyell's syndrome, anaphylactic shock;
    SSS: heart rhythm disturbance, leukopenia, thrombocytopenia, agranulocytosis, arterial hypertension, neutropenia, anemia, pancytopenia;
    urinary system: oliguria, nephrotoxic effect, renal colic;
    other: hyperhidrosis, changes in blood glucose.

Instructions for use Coldrem Hotrem (Method and dosage)

For those who take Coldrex Hotrem powder, the instruction manual recommends using the sachet approximately every 4 hours. The daily dosage is maximum for 6 sachets.
Instructions for Coldrex Hotrem informs that the powder should be poured into a glass with warm water, stir until it completely dissolves, and add cool water.
The maximum duration of drug use is 5 days.

Overdose

The dose of the drug specified in the instruction can not be exceeded. In case of overdose, it is necessary to consult a doctor even if there are no clearly expressed negative symptoms, as there is a possibility of serious damage to the liver, encephalopathy, coma, and metabolic acidosis.
Overdose can cause nausea, headache, loss of appetite, vomiting, pallor, pain in the epigastric region. In addition, in severe cases, possible hypertension and hepatotoxic effect of the drug. Manifestations of toxic reactions due to paracetamol overdose usually occur within 12-48 hours. In this case, the use of Acetylcysteine ​​and Methionine is indicated.
In case of an overdose it is also possible to wash the stomach and use enterosorbents. Treatment is symptomatic.

Interaction

When combined with barbiturates, carbamazepine, diphenin, rifampicin, zidovudine and other inducers of microsomal hepatic enzymes, taking the medication can cause a hepatotoxic effect.
Coldrex Hotrem can not be taken together with other products containing paracetamol. In addition, reception with MAO inhibitors, tricyclic antidepressants and beta-blockers is contraindicated, and also within 14 days after their withdrawal.

Terms of sale

You can buy Coldrex Hotrem without a prescription.

Storage conditions

The medicine should be protected from children. Store at room temperature.
Shelf life - three years.

Reviews

Those who leave feedback on Coldrex Hotrem powder report the following advantages of the drug:
    efficiency;
    quick action;
    pleasant taste;
    the presence of various flavors (lemon, currant);
    convenient packing;
    ease of use;
    possibility to buy by the piece;
    availability in pharmacies.
Among the shortcomings of the remedy are the presence of contraindications and side effects, as well as a high price.