Ibuclin tabs 400mg+325mg #10

User manual for Ibuclin

You can buy Ibuclin tablets here

Composition

The composition of the drug includes active ingredients ibuprofen (400 mg) and paracetamol (325 mg), as well as the following auxiliary substances: corn starch, MCC, sodium carboxymethyl starch (type A), glycerol, talc, silicon dioxide colloid, magnesium stearate.

Form of issue

Produced in the form of capsular tablets with an orange film shell, on one side of the shell - the risk. Marble color is acceptable. Tablets are packed in blisters for 10 pcs., Sold in cardboard boxes of 10 and 20 pcs.
Ibuclin Junior for children - soluble tablets of round shape with risks, pink, with splashes. They have mint flavor.

pharmachologic effect

The preparation has a combined composition, its effect is determined by the action of the components.
Ibuprofen has an anti-inflammatory, analgesic, antipyretic effect on the body. Under its influence, the number of prostaglandins decreases both in the focus of the inflammatory process and in healthy tissues. This effect is due to the inhibition of cycloxygenase, a violation of the metabolism of arachidonic acid. Also exudative and proliferative phases of the inflammatory process are suppressed.
Paracetamol provides non-selective blocking of COX, has little effect on the mucosa of the gastrointestinal tract and on water-salt metabolism. Provides antipyretics and analgesia.
In combination, the effectiveness of the effects of components is more pronounced than individually.
The drug contributes to the weakening of arthralgia at rest and during movement, reduces the feeling of morning stiffness and swelling of the joints, increases the volume of movements.

Pharmacodynamics and pharmacokinetics

Ibuprofen is almost completely and very quickly absorbed from the digestive tract. The maximum concentration after oral administration occurs in 1-2 hours. Communication with plasma proteins is more than 90%. Ibuprofen is slowly absorbed into the joint cavity creating in the synovial fluid concentrations higher than in the blood plasma. Exposed to metabolism. 90% of the body is excreted through the kidneys, a smaller part is excreted as metabolites and their conjugates with bile.
Paracetamol is rapidly adsorbed, its association with plasma proteins is less than 10%, with an overdose it slightly increases. The maximum concentration occurs after 0.5-2 hours. In liquid body fluids, paracetamol is distributed relatively evenly.
90-95% of the substance is metabolized in the liver. A small part is hydroxylated by microsomal enzymes. In breast milk, a small amount of paracetamol is ingested - less than 1% of the dose.

Indications for use of Ibuclin

Indications for use of the drug (from which tablets Ibuclin used for symptomatic treatment):
    febrile conditions, including those due to colds or flu;
    attacks of neuralgia;
    myalgia;
    painful sensations of different intensity in the back;
    pain in the joints, pain arising from diseases of the musculoskeletal system;
    toothache;
    pain caused by dislocations, sprains, fractures, severe bruises;
    painful menstruation;
    pain syndrome postoperative or post-traumatic nature.
From what Ibuclin is used in the treatment of children, the pediatrician will explain in more detail. It is necessary to know exactly what the drug is used for and how it helps, because it can only reduce pain and inflammation during use. The progress of the disease as a whole does not affect its use.

Contraindications

Contraindications for Ibuclin treatment are:
    a high level of sensitivity to the components that make up the drug;
    acute form of duodenal ulcer or stomach;
    bleeding in the stomach or intestines;
    inflammatory processes in the intestine;
    severe form of kidney failure, progressive kidney disease;
    defeat of the optic nerve;
    bronchial asthma, polyposis of the nose and paranasal sinuses, combined with intolerance to acetylsalicylic acid and other NSAIDs;
    diseases of the circulatory system;
    liver disease in acute form or severe course of hepatic insufficiency;
    hyperkalemia;
    III trimester of pregnancy.

Side effects

The drug can provoke the occurrence of some side effects when used for adults and children:
    In the functions of the gastrointestinal tract: symptoms of NSAIDs-gastropathy (vomiting, nausea, heartburn, epigastric pain, diarrhea); there are fewer violations of liver function, erosion and ulcers, bleeding, pancreatitis, dry mouth, constipation, stomatitis.
    In the functions of the nervous system: increased anxiety, dizziness, headache, agitation, depression, hallucinations; less noticeable decrease in hearing, vision, double vision, aseptic meningitis, amblyopia.
    In the functions of the cardiovascular system: increased blood pressure, tachycardia, heart failure.
    In the functions of the hematopoiesis: thrombocytopenic purpura, anemia of thrombocytopenia, leukopenia.
    In the functions of the respiratory system: bronchospasm, dyspnea.
    In the functions of the genitourinary system: acute renal failure, edema, allergic nephritis, polyuria, cystitis.
    The onset of allergic reactions.
    Change in laboratory indicators: decrease in glucose, hematocrit, hemoglobin; an increase in the period of bleeding, an increase in the activity of hepatic transaminases.
    Severe sweating.
If Ibuclin from the temperature of the patient takes in high doses for a long period, ulcers of the mucosa of the gastrointestinal tract, bleeding, vision problems may appear. In this case, you need to visit a doctor to replace the tablets from the temperature with another drug.

Instructions for the use of Ibklin (Method and dosage)

Instruction on Ibuclin is as follows: the medicine is taken orally, before eating, or 2-3 hours after eating. Tablets do not need to be chewed, washed down with a lot of water.
Adults need to take one tablet of Ibuclin three times a day. Three tablets are the maximum allowable dose of the drug. Between taking the tablets should take at least 4 hours. For the elderly and for those who suffer from impaired renal and hepatic function, the interval between taking the tablets should be at least 8 hours.
Children who are 12 years old and who have a body weight of more than 40 kg take 1 tablet 2 times a day.
Treatment with Ibuclin to reduce the temperature can last no more than three days. The use of the drug as an anesthetic is possible for no more than five days. If you need to continue therapy, you should first consult with your doctor.
Instructions for the use of child Ibuclin are as follows: one tablet of the drug Ibuclin Junior is dissolved in one teaspoon of warm water. Dosage Ibuclin Junior for children is made according to their weight.
    At a weight of 11-15 kg - 1 tablet 1 time in 8 hours, 3 times a day;
    At weight 16-21 kg - 1 tablet 1 time in 6 hours, 4 times a day;
    At weight 22-40 kg - 2 tablets once in 8 hours, 3 times a day;
    At a weight of more than 40 kg, the minimum dose for adults is taken.

Overdose

In case of an overdose, the following symptoms may occur:
    disorders of the gastrointestinal function, accompanied by nausea, vomiting, diarrhea, pain in the epigastric region;
    bleeding occurring after 12-48 hours;
    state of retardation, depression, drowsiness;
    headache;
    violation of the heart rate, lowering blood pressure;
    convulsions;
    impaired consciousness;
    noise in ears.
If there is a suspicion of an overdose, you should immediately seek help from a doctor. In case of an overdose, gastric lavage is practiced during the first 4 hours after taking the drug, drinking alkaline drink, activated charcoal, conducting forced diuresis. Symptomatic treatment is performed. Other methods of therapy the doctor determines individually, depending on the concentration of Ibuclin components in the body.

Interaction

Simultaneous administration of drugs containing ibuprofen and acetylsalicylic acid reduces the anti-inflammatory and anti-aggregation effect of the latter.
Wikipedia indicates that the interaction of the drug with GCS, ethanol, corticotropin increases the likelihood of erosion and ulcers of the gastrointestinal tract.
Ibuprofen activates the effect on the body of thrombolytic agents, direct and indirect anticoagulants, colchicine, antiplatelet agents. As a consequence, the risk of hemorrhagic complications increases. Also increases the hypoglycemic effect of insulin and oral medications with hypoglycemic effect.
When combined with hypotensive agents and diuretics, their effectiveness decreases. The analgesic effect of ibuprofen is enhanced by caffeine. When taking gold preparations, cyclosporine with ibuprofen, nephrotoxicity increases. With the simultaneous administration of antacids and colestyramine, the absorption of Ibuclin is reduced.

Terms of sale

You can buy Ibuclin without a doctor's prescription.

Storage conditions

Store the drug in a dry place, which does not receive rays of light. The temperature should not be more than 25 ° C. The drug should be protected from children.
Shelf life - 5 years.

special instructions

The abstract indicates that the drug should be treated with caution in CHD, chronic heart failure, diabetes mellitus, peripheral arterial diseases, history of gastrointestinal ulcers, Helicobacter pylori infection, liver cirrhosis, nephrotic syndrome. Also, the drug is used cautiously for the treatment of elderly people, smokers, those who regularly consume alcohol.
It is not necessary to simultaneously take Ibuclin and other drugs that have a composition of paracetamol, NSAIDs.

Children

Ibuclin is not prescribed for treatment of children under 12 years.
Ibuclin Junior is not assigned to children under three years of age.

With alcohol

If the patient simultaneously takes Ibuclin and spirits, the likelihood of hepatotoxic effect increases. Therefore, during treatment with this drug, alcohol should not be taken.

With antibiotics

Sometimes patients have a question about whether Ibuclin is an antibiotic or not. The answer is unequivocal: this drug is not an antibiotic. If necessary, in parallel with the reception of Ibuclin, antibiotic therapy is prescribed, however, complex treatment is carried out only under the supervision of a doctor.

In pregnancy and lactation

If there is a need to take Ibuclin during pregnancy and during breastfeeding, the expected benefits of treatment and the likely risk are clearly determined. In the first trimester of pregnancy, if necessary, short-term treatment with the drug is possible. With a short reception of Ibuclin during lactation, as a rule, to stop the process of feeding is not necessary.

Reviews on Ibuclin

Reviews of doctors and patients indicate that Ibuclin effectively reduces body temperature in both adults and children. According to people who took the drug, he quickly removes the pain syndrome, has a pronounced antipyretic effect. Side effects are rare. Reading reviews on children's Ibuclin, it can be noted that most parents note as side effects the appearance in children of loose stools, pain in the abdomen.
Nevertheless, Ibuclin for children is a very popular and effective drug. The testimonies testify that it can be given to children who do not lose other drugs at elevated body temperature. If the correct dosage for children is observed, then the drug has an effect faster and more pronounced than another syrup or tablet.