Rehydron powder #20

Rehydron instruction for use

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Composition

The composition of Rehydron includes 10 g of dextrose, 3.5 g of sodium chloride (Sodium chloride), 2.9 g of sodium citrate (Sodium citrate), 2.5 g of potassium chloride (Potassium chloride).
In the solution obtained by dissolving 1 dose of powder (the contents of one sachet) in 1000 mg of water, the active ingredients are contained in the following concentrations: NaCl - 59.9 mmol, KCl - 33.5 mmol, Na citrate (in the form of dihydrate) 9, 9 mmol, dextrose 55.5 mmol, citrate ions 9.9 mmol, Cl- 93.4 mmol, K + -33.5 mmol, Na + 89.6 mmol.

Form of issue

Powder for drinking. Pouches of 18.9 grams, package number 20.

pharmachologic effect

Hydrating.

Pharmacodynamics and pharmacokinetics

What is Rehydron?

The drug solution is used to correct loss of body fluids and electrolytes in vomiting and / or diarrhea.

Pharmacodynamics

The glucose in the preparation contributes to the absorption of citrates and salts, which helps maintain metabolic acidosis.
The osmolarity of the finished solution is 260 mOsm / l, and its medium is slightly alkaline (pH 8.2). In comparison with the standard solutions that WHO recommends for use in rehydration therapy, Rehydron has a lower osmolality. The sodium content in it is also lower than that of analogues, and the potassium concentration is slightly higher.
There is ample evidence that hypoosmolar solutions are more effective, a lower concentration of sodium can prevent the development of hypernatremia, and an elevated level of potassium promotes a more rapid recovery of potassium levels.

Pharmacokinetics

The pharmacokinetics of glucose, electrolytes and water that are part of the solution, corresponds to the nature of the pharmacokinetics of these substances in the body.

Powder Rehydron: indications for use

Indications for the use of Rehydron are conditions accompanied by a disturbance of the water-electrolyte balance (VEB).
On the question of what helps the medicine Rehydron, the manufacturer in the annotation to the drug indicates that the use of the tool is advisable:
    if necessary, correcting the acidosis in diarrhea, which is accompanied by mild or moderate dehydration (for example, adults and children drink the solution when the weight loss is 3-10%);
    with thermal lesions associated with violations of EBV;
    in cases of dangerous desalination of the body, when the level of chloride in urine does not exceed 2 g / l.

Powder - what is it used for preventive purposes?

The prophylactic use of Rehydron is indicated in cases of intense physical and thermal stresses (when the body loses 750 grams (or more) grams of weight per hour), as well as in situations where during a working day a person loses more than 4 kg of weight.

Why do we need Rehydron for children?

As well as adults, children are prescribed for children with a threat of dehydration, including vomiting and diarrhea, which are a consequence of gastrointestinal infections, as well as in situations where dehydration develops against a background of heat stroke.
However, if the child's chair is watery and bloody impurities are present, the body temperature rises above 39 ° C, the child looks drowsy, sluggish and exhausted, urination stops, acute pain in the abdominal cavity occurs, and diarrhea and vomiting occur more often five times per day, you need to urgently consult a doctor.

Contraindications

In the manufacturer's annotation the following contraindications to the use of the drug are listed:
    intestinal obstruction;
    unconsciousness;
    renal dysfunction;
    cholera-related diarrhea;
    intolerance of the components of Rehydron.
A relative contraindication is diabetes mellitus (type I or II).

Side effects

When the recommended doses are observed, the incidence of side effects is extremely low. The development of hypersensitivity reactions is potentially possible.
With normal kidney function, the risk of hyperhydration or hypernatremia when using rehydration solution is low. If the agent is administered too quickly, vomiting is possible.

Powder Rehydron: instructions for use

How to grow a powder and how to drink adults solution Rehydron?

Rehydron is taken inside at any time of the day, without being tied to the time of ingestion.
To prepare the rehydration solution, the powder is dissolved in a warm (optimal temperature 35-40 ° C) boiled water. For therapeutic purposes, 2.39 grams of powder should be diluted in 0.5 cups of liquid (100 ml), 11.55 grams of powder take half a liter of water, 23.9 grams - 1 liter.
If Rehydron is taken for prophylactic purposes, two times more water should be used to dissolve the powder: 200 ml, 1 and 2 liters, respectively.

How to take Rehydron to adults?

With diarrhea of ​​mild severity, the daily dose of the solution is 40-50 ml / kg. At a diarrhea srednjjazhelogo currents a daily dose from 80 up to 100 ml / kg. Treatment usually lasts 3-4 days. A signal to stop it is the end of diarrhea.
For maintenance therapy before restoring a disturbed EBV and stopping diarrhea, the solution should also be taken at a rate of 80-100 ml / kg / day.
In the first six to ten hours the patient should receive Rehydron in a volume that is twice as large as the loss of body weight provoked by a stomach disorder. At this stage of treatment, there is no need to introduce other liquids.
If diarrhea continues and after correction of dehydration, the patient during the day should be summarily received depending on the weight of 8.3 to 27 liters of liquids. To compensate for the needs of the body use Rehydron, water and other liquids. The outpatient scheme is chosen by the doctor depending on the age and weight of the patient.
For nausea and / or vomiting, it is better to drink liquid chilled and small repetitive doses. A nasogastric tube can be used, but in this case rehydration should be performed under the supervision of a physician.
With convulsions (thermal or provoked by a drinking disease) and other violations of VEB, fractional - 100-150 ml - Rehydron is indicated. In the first half hour, the patient should receive from 0.5 to 0.9 l of a solution of rehydration salts.
Then, until the symptoms of heat damage and water / electrolyte deficiency completely disappear, the patient should receive the same dose of solution every forty minutes,
To prevent VEB violations in extreme physical or thermal stress, the solution is taken in small sips every time you feel thirsty. Stop taking as thirst quenches.

The use of Rehydron for poisoning

When poisoning, Rehydron is taken irrespective of the time of ingestion, often in small sips (a large amount of fluid taken at one time can cause another attack of vomiting).
The dose is calculated depending on the weight of the patient. So, for example, an adult with a weight of 80 kg during the first hour should receive 0.8 liters of solution (10 ml / kg).
As the patient's condition improves, the dose is reduced to 5 ml / kg. If the symptomatology is resumed, the amount of medication administered is again increased to the original one.

How to breed Rehydron for children?

According to instructions for the use of Rehydron for children, for the preparation of drinking the contents of one package should be diluted in liter of boiled water to the temperature of the body. With diarrhea in young children, the powder must be diluted in a larger volume of water to reduce the sodium concentration in the finished solution.
The ready-made solution can be used for 24 hours, but it should be stored in the refrigerator.
A solution of Rehydron for children is recommended to drink after each liquid stool in small sips.
Instruction on Rehydron for children warns that the drug should not be combined with other medicines and diluted in any other liquid except water.

How to take Rehydron to children?

Before starting treatment, the child should be weighed to assess the degree of dehydration and weight loss.
Nutrition or breastfeeding during the use of the drug is not interrupted or resumed immediately after rehydration. During treatment in the diet should not be rich in simple carbohydrates and food fats.
The use of the drug begins as soon as the child begins diarrhea. Treatment, like in adults, lasts 3-4 days, before the normalization of the stool.
In the first ten hours, Rehydron for children should be used at a dose of 30-60 ml / kg (taking into account the degree of dehydration). The average dose for a child is 2-3 tbsp. spoon for one kilogram of body weight. When the symptoms of dehydration decrease, the dose can be reduced to 10 ml / kg.
Newborn infants and young children during the first four to six hours give a medication of 5-10 ml every five to ten minutes.
When vomiting, the baby should be given a chilled solution.
An important rule of rehydration therapy for gastrointestinal infections is the lack of abundant drinking and food. If a child asks for food, preference should be given to low-fat, light foods.

Overdose

When using a too concentrated solution, as well as taking an excessively large amount of solution, the risk of hypernatremia is high. With reduced renal function, hyperkalemia and metabolic alkalosis are possible.
Hypernatremia manifests itself:
    neuromuscular excitation;
    weakness;
    confusion of consciousness;
    drowsiness;
    coma;
    stopping breathing.
Manifestations of metabolic alkalosis are neuromuscular excitation, reduced ventilation of the lungs, tetanic convulsions.
With a severe overdose with severe symptoms of hypernatremia or metabolic alkalosis, the introduction of Rehydron is discontinued. Further treatment is carried out taking into account the results of laboratory studies.

Interaction

The drug interaction was not studied. Since the solution of Rehydron has a slightly alkaline reaction, it can affect the means, the absorption of which depends on the acidity of the contents of the intestine.
It should be borne in mind that diarrhea itself has an effect on the absorption of drugs absorbed in the thin / thick intestine, as well as the absorption of drugs with their enterohepatic circulation.

Terms of sale

Without recipe.

Storage conditions

Packets of powder should be stored at a temperature of 15 to 25 degrees Celsius in a place inaccessible to children. The solution of Rehydron is suitable for use within 24 hours from the moment of preparation (the medicine should be stored in the refrigerator).

Shelf life

Three years.

special instructions

In severe dehydration, when the loss of body weight exceeds 10%, and the patient develops anuria, the treatment begins with the use of rehydration funds for intravenous administration and only after that appoint Rehydron.
Do not exceed the established dose if the deficiency of ions of electrolytes is not confirmed by laboratory tests.
Using a too concentrated solution can trigger the development of hypernatremia, therefore, do not exceed the manufacturer's recommended dose.
Do not add sugar or honey to the solution. Food can be consumed immediately after rehydration.

Rehydron when vomiting to children and adults is given ten minutes after the attack. The medicine should be drunk in small sips and slowly.
If dehydration is a consequence of diabetes mellitus, CRF, or any other chronic pathology in which electrolyte, acid-base or carbohydrate balance is disrupted, rehydration with Rehydron requires careful monitoring of the patient's condition.
The appearance of a liquid bloody stool, the inability of the patient to answer questions, rapid fatigue, speech slowing, drowsiness, fever to 39 degrees or more, anuria, diarrhea lasting more than five consecutive days, as well as its sudden cessation in the presence of severe pain, are the occasion for immediate medical attention.
Treatment at home in these cases is impossible and inefficient.

Rehydron does not slow down the reaction speed, does not hamper thinking processes and does not affect the ability to control machinery or vehicles.

Regiodron during pregnancy

In established doses, the drug can be used during pregnancy and during breastfeeding.

Reviews of Rehydron

Rehydron is an easy-to-use and very effective means for preventing dehydration during vomiting and diarrhea. Most people who leave reviews about Rehydron, believe that the drug should be in every medicine cabinet.
Its only drawback is that many patients refer to the specific taste of the solution. If an adult still manages to drink the right amount of medicine, then persuading the child to take even a portion of the required dose is often quite difficult.
For this reason, many mothers advise choosing for children not Regiodron, but its analogues with a more pleasant taste (for example, Rehydron Optim, which differs from Rehydron with the concentration of active substances and the presence of lemon flavor in the auxiliaries).