Cerucal tabs 10mg #50

Instruction for Cerucal tabs

Reed more and buy Cerucal online

Composition

The active substance is metoclopramide hydrochloride monohydrate.
In 1 tablet contains 10, 54 mg of this substance, which in terms of metoclopramide hydrochloride is 10 mg.
Additional substances are: silicon dioxide, potato starch, gelatin, magnesium stearate and lactose monohydrate.
In 1 ml of the solution contains 5 mg of metoclopramide hydrochloride. Additional substances are: edetate disodium, injection water, sodium sulfite, sodium chloride.

Form of issue

The drug is available in the form of tablets and a solution for intravenous and / or injections.

pharmachologic effect

Antiemetic drug.

Pharmacodynamics and pharmacokinetics

The active ingredient is metoclopramide. The main substance is a blocker of serotonin and dopamine receptors. Cerucal eliminates hiccups, heartburn, accelerates the emptying of the stomach, tones up the lower sphincter of the esophagus, significantly reduces and slows the motor activity of the esophagus, does not cause diarrhea, speeds up the movement of food through the small intestine. The drug stimulates the release of prolactin.
After intravenous administration, the effect of the drug is felt after 1-3 minutes, when administered intramuscularly - after 10-15 minutes. The drug is metabolized in the liver. Output is in the initial state of about 20% and about 80% metabolites.

Indications for the use of Cerucal

From what tablets and ampoules?

The drug is prescribed for hiccups, vomiting, hypotension and atony of the intestine, stomach, with reflux-esophagitis, dyskinesia of the bile ducts, exacerbation of ulcerative lesions of the digestive system, flatulence. What are the other indications for the use of Cerucal? To enhance peristalsis, the drug is used in radiocontrast studies of the digestive tract.

Contraindications

Cerucal is not prescribed for bleeding in the digestive system, with intolerance to metoclopramide, pheochromocytoma, perforation of the intestine and stomach, mechanical intestinal obstruction, stenosis of the pylorus, epilepsy, extrapyramidal disorders, with prolactin-dependent tumors, Parkinson's disease. With arterial hypertension, bronchial asthma, kidney pathology, liver, in pediatrics appoint with caution.

Side effects

Cerucal can cause the following side effects: diarrhea, constipation, drowsiness, dizziness, dry mouth, depression. Long-term use of high doses by the elderly causes gynecomastia, dyskinesia, the phenomenon of parkinsonism, galactorrhea. In case of an overdose, extrapyramidal disorders, disorientation, hypersomnia are recorded. After the drug is discontinued, the symptoms disappear after a day.

Instructions for the use of Cerucal (Method and dosage)

Tablets Cerucal, instructions for use

The drug is taken orally 30 minutes before meals three times a day for 5-10 mg. It is recommended to take a tablet with a large amount of liquid. The maximum daily dose of 60 mg, single 20 mg.

Cerucal injections, instructions for use

Adults and at the age of 14 years enter intramuscularly or slowly intravenously, one ampoule 1-3 per day.
Children from 2 to 14 years of age should be injected at a rate of 0.1 mg / kg, the maximum allowable dose per day is 0.5 mg / kg.

Overdose

The following phenomena are observed: hallucinations, drowsiness, irritability, convulsions, lowering of consciousness level and its confusion, stopping of respiratory and cardiac activity, anxiety, extrapyramidal disorders, cardiovascular system disorders, dystonic reactions.
In case of an overdose, symptomatic treatment should be used.

Interaction

Anticholinesterase drugs weaken the action of metoclopramide. Cerucal increases the absorption of paracetamol, Ampicillin, tetracycline, ethanol, levodopa, ascorbic acid. The drug reduces the absorption of cimetidine, digoxin. It is inadmissible simultaneous administration of neuroleptics (increased risk of extrapyramidal disorders).

Terms of sale

To buy Cerucal you don't need a prescription.

Storage conditions

In a dark place inaccessible to children at a temperature of no higher than 25 degrees Celsius.
Shelf life not more than 5 years.

special instructions

According to the annotation in some cases it is recommended to additionally apply anti-Parkinsonics, central holinoblokatory. It is inadmissible to use ethanol in the treatment with Cerucal. The drug affects the performance of complex activities, driving a car.
INN: Metoclopramide.
The medicine is used in veterinary medicine for cats and dogs.

Cerucal for children

The drug is contraindicated for children under 1 year.
The dosage of Cerucal for children is as follows: 0.1 mg / kg body weight up to 3 times a day. The maximum daily dose is 0.5 mg / kg body weight.
To prevent postoperative vomiting, use the drug after the operation. Maximum should be used no more than 2 days.

Cerucal during pregnancy

According to experiments, Cerucal during pregnancy does not cause toxic damage to the fetus, however, in recent terms, it is impossible to exclude the appearance of extrapyramidal syndrome in infants. Therefore, the drug should be administered with caution by a qualified doctor, you should avoid using the medication on the final terms of pregnancy.
When breastfeeding is not recommended to use medication.

Reviews of Cerucal

Removes nausea and vomiting for several minutes. According to reviews, Cerucal is really effective, but it has a number of serious side effects, as well as contraindications. When used, the exact dosage is important.