Chophytol tabs #180

User manual for Chophytol

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Composition

One Chophytol tablet contains 200 mg of dried Cynara Scolymus leaves (artichoke field), pregelatinized corn starch - 22 mg, talc - 3 mg, magnesium trisilicate - 12 mg, magnesium stearate - 3 mg. The composition of the shell: talcum - 16.3 mg, rosin 1.152 mg, gum milak 1.152 mg, sucrose 86.146 mg, gelatin 0.384 mg, calcium carbonate 2.2 mg, carnauba wax 0.082 mg, polysorbate 80 0.004 mg, brown, black and yellow, sucrose), additives E214 and E 218 (ethyl and methyl parahydroxybenzoate).
The composition of the solution of Chophytol includes a dense aqueous extract of Cynara Scolymus leaves (artichoke field) in a concentration of 20 g per 100 ml, ethyl alcohol, orange flavor, methyl parahydroxybenzoate, propyl parahydroxybenzoate, glycerol, purified water.

Form of issue

    Tablets in a film shell. Tablets biconvex, round, in blisters (5 to 12 tablets / 2 to 30 tablets / 6 to 30 tablets) or polypropylene tubes (60 tablets / 180 tablets).
    Solution for oral administration (in the form of a suspension or syrup) in bottles of dark glass of 120 ml.

pharmachologic effect

Cholagogue.

Pharmacodynamics and pharmacokinetics

The drug Chophytol - its action?

Pharmacological properties of the drug are due to the action of a complex of biologically active substances contained in the leaves of Cynara Scolymus. Tsinarin in combination with phenolic acids has a hepatoprotective and choleretic effect. Carotene, inulin, ascorbic acid and vitamins B1 and B2 contribute to the normalization of metabolic processes.
Chophytol promotes the activation of bile formation and bile secretion, a decrease in the level of urea and cholesterol in the blood.

Pharmacokinetics

Carrying out kinetic observations and identifying metabolites of the drug is not possible, since the effect of Chophytol is the cumulative effect of its active substances.

Indications for use of Chophytol

Injectable solution, drops and Chophytol tablets - what are they from?
    dyspeptic disorders, manifested by nausea, flatulence, heartburn, a feeling of heaviness in the epigastric region;
    chronic non-calculous (tubeless) cholecystitis;
    chronic hepatitis;
    dyskinesia of bile ducts (DZHVP) by hypokinetic type (characterized by slowing and lethargy of bile outflow);
    cirrhosis of the liver;
    chronic renal failure;
    chronic nephritis.
In combination with other medicines artichoke field preparations can be used to treat:
    chronic intoxication (salts of heavy metals, alkaloids, nitro compounds, hepatotoxic substances);
    anorexia;
    obesity;
    atherosclerosis;
    uraturia;
    urolithiasis.

Contraindications

The drug is not prescribed with known hypersensitivity to the components of tablets / solution (in particular to preservatives E214, E216 or E218) and plants of the family of astroids (Asteraceae or Compositae).
Other contraindications to the use of Chophytol:
    obstruction of the biliary tract;
    cholelithiasis;
    acute diseases of the kidneys, liver, urine and biliary tract (angiocholitis, empyema of the gallbladder, etc.);
    children's age to six years (for the tablet form of the drug).

Side effects

Long-term use of the drug in high doses can cause:
    cramping in the abdomen;
    heartburn;
    diarrhea;
    nausea;
    upset stomach.
In some patients, the side effects of Chophytol are manifested in the form of hypersensitivity reactions (skin rashes, urticaria, pruritus and skin hyperemia).

Instructions for use of Chophytol (Method and dosage)

Chophytol tablets, instructions for use

For patients over the age of twelve, tablets are prescribed to take three times daily (before meals) one or two each time (daily dose from 600 mg to 1.2 g).
Treatment, as a rule, lasts from 2 to 3 weeks. If necessary, the doctor can prescribe a second course.

Chophytol solution, instructions for use

Before oral administration, the oral solution is shaken and diluted with water. Single dose for an adult 2.5 - 5 ml (1 tsp). Multiplicity of applications - 3 times a day.
The duration of treatment depends on the nature and characteristics of the course of the disease.

Overdose

Overdose may increase the side effect of the drug.

Interaction

There are no data on the interaction of Chophytol tablets with other drugs in the manufacturer's instructions. Clinical studies of the interaction were not conducted.
It should be taken into account that ethanol (0.13 g per 1 tsp of drug) is contained in the oral solution. Therefore, care should be taken when using drops with CNS suppressive agents at the same time.

Terms of sale

Tablets and solution - without a prescription.

Storage conditions

Store Chophytol at room temperature in a place inaccessible to children.

Shelf life

The shelf life of the tablets is three years, the solution is four years.

special instructions

    Chophytol should be used with extreme caution in pathologies that can potentially provoke obstruction of the biliary tract, as well as in severe liver pathologies.
    The occurrence of abdominal pain and / or diarrhea should serve as an excuse for stopping treatment and contacting a doctor.
    The tablets contain sucrose (0.08 grams / tab.), Which should be taken into account in patients with glucose-galactose malabsorption syndrome, fructose intolerance or a deficiency of isomaltase sucrose.
    The presence of preservatives in the tablets and oral solution may cause hypersensitivity reactions (including deferred).
    The oral solution contains ethanol in its composition, therefore during the period of treatment with Chophytol in this dosage form it is recommended to avoid drinking beverages that contain alcohol.
    The tablets and the injection solution do not slow down the reaction rate and do not interfere with the ability to concentrate attention. Drops for ingestion due to the presence of ethanol in their composition can influence these parameters, which should be remembered when driving and when working with machinery.

Which is better: Allochol or Chophytol?

Allochol, like Chophytol, is designed to treat liver and bile duct pathologies. Its basis are Activated Carbon (enterosorbent), bile, garlic bulbs of inoculum and leaves of nettle dioecious.
The drug has choleretic properties (it has a cholekinetic effect and causes a moderate choleretic effect), enhances the secretory function of the liver, reflexively increases the motor and secretory organs of the digestive system, improves the digestive process in general and, in particular, emulsifies edible fats, reduces the cholesterol precipitation probability from the subsequent formation of stones.
Active components of Allochol also contribute to suppressing the processes of fermentation in the intestinal tract and thereby reduce flatulence.
Allochol is prescribed for the treatment of cholangitis, chronic reactive hepatitis, DZHVP, postcholecystectomy syndrome, atonic constipation.
Cholagogue agents are prescribed only in the absence of signs of inflammation. The choice in favor of a given drug is made taking into account the type of dysfunction, and also depending on how quickly you need to get a positive result from therapy.
Both Allochol and Chophytol are true choleretics, since both increase the secretion of bile and stimulate the formation of bile acids, but Chophytol besides choleretic has also a protective effect.
Proceeding from this, it can be concluded that the use of bile-containing drugs is expedient if it is necessary to conduct long-term course treatment with biliary dysfunction, the choice is in favor of Chophytol in situations when the patient simultaneously diagnoses liver pathology.

Chophytol in pediatric practice

In pediatrics solutions for oral / parenteral administration are prescribed without age restrictions, tablets for children over six years of age.
Indications for use in children are acute or chronic hepatitis, chronic stone cholecystitis, fatty hepatosis, motor disorders and a decrease in the tone of the gallbladder and its ducts, an increase in the concentration of acetone in the blood, intoxication (salts of heavy metals, nitrates, etc.), oliguria, chronic renal failure , chronic nephritis, skin diseases (acne in adolescents, psoriasis, etc.), dyspeptic disorders, obesity, jaundice of newborns.
Children over the age of twelve are scheduled to take pills at the same dose as adults. The daily dose of tablets Chophytol for children 6-12 years - 600 mg (the dose should be divided into three doses).
The optimal dosage form for newborns are drops. According to the instructions for Chophytol, for infants it is necessary to measure 5-10 drops of medication for each dose. The medicine is given on an empty stomach 3 r. / Day .. Before giving the child Chophytol in drops, the required dose is preliminary dissolved in 5 ml of water.
Teenagers over the age of twelve 2.5-5 ml of the solution are bred in 1 tbsp. l. water. Children under the age of twelve are required to take 2-3 milliliters (depending on the age and indications) for a similar volume of water. Take this dose should be 3 r. / Day. 20 minutes before meals.
Reviews of Chophytol for children indicate that the drug not only copes very well with the task, but is also very well tolerated by small patients. In addition, the drug is very convenient to use and easy to dose, which is very important when it comes to treating infants.
For newborns, the reviews are a confirmation, the drug is prescribed primarily in cases where the child has a long period of physiological jaundice.
Excessive increase in the concentration of bilirubin in the blood with pathological jaundice is dangerous because it can lead to the development of noninfectious damage to the structures of the brain.
The timely use of Chophytol for newborns helps normalize liver function and biotransformation of insoluble toxic indirect bilirubin in a non-toxic direct. The mothers of small children note that the child's bilirubin decreased on average by the ninth day of life, and by the end of the second or third week the symptoms of jaundice completely disappeared.

Chophytol in pregnancy

What is the prescription for the drug?
What is Chophytol for pregnancy? The instructions state that the use of Chophytol in pregnant women is allowed according to the doctor's prescription and provided that the expected result of treatment exceeds the probable risks to the fetus or the child.
In the first months of pregnancy, the drug, with the available risk factors prescribed for the prevention of late gestosis, as well as to ease the condition of women with early toxicosis. There is evidence that the inclusion of Chophytol in the treatment of pre-eclampsia contributes to improving the clinical course of the disease.
In pregnancy, the drug acts as an antioxidant and hepatoprotector. It reduces oxidative degradation of lipids under the influence of free radicals, improves the metabolism of fats, protects the liver and facilitates its work, stimulates the formation and excretion of bile, has a mild diuretic effect, lowers cholesterol in the blood, improves blood and microcirculation (including the placenta) .
Despite the fact that the drug is not a special gynecological or obstetric agent, it is used to improve the condition in liver pathologies, atherosclerosis, inflammatory diseases of the urinary tract.
Against the background of the application of Chophytol, the overall well-being of pregnant asthenic type also improves. Women are much less likely to be disturbed by weakness, dizziness, mood swings, drowsiness, and CNS excitability decreases.
One of the problems of pregnant women is fluid retention in the tissues. Because of this, pregnancy is often complicated by quite serious pathologies. Chophytol also improves the functioning of small vessels and kidney function, thus preventing the development of edema and dropsy.
Nevertheless, it must be taken into account that the preparation does not possess antiseptic and antibacterial properties. Therefore, if there are signs of inflammation during a blood test, Chophytol alone is not enough. Along with it it is necessary to take uroseptic medications permitted for pregnant women.
Reviews of Chophytol during pregnancy are more often good. Most women claim that the drug helped them well in case of toxicosis, heartburn and edema. However, there are also such reviews, which note that the result was not noticeable even after the completion of the full course.

What dosage is considered optimal during pregnancy?

How to take Chophytol during pregnancy? The optimal dosage of tablets during pregnancy is 500 mg / day. The medication is usually taken within three weeks.
In the form of an oral solution, Chophytol is taken three times a day in a teaspoonful (5 ml). The course of treatment is usually about two weeks.
The doctor determines the duration of the course individually.

Application of Chophytol in lactation

Data on the safety of the use of the drug during the period of breastfeeding are not provided.

Reviews about Chopytol

Befor you buy online Chophytol, see Reviews below:
Chophytol is intended to enhance gallbladder motility and restore normal bile flow in dysfunctional biliary tract disorders.
The drug has hepatoprotective and diuretic properties, which makes it possible to use it not only in DZHVP and chronic pathologies such as nephritis, hepatitis or cholecystitis, but also in pregnancy (to reduce the symptoms of early toxicosis and treatment of late gestosis), with newborn jelly and slimming in the framework of obesity treatment programs (as an aid).
If you examine the feedback of doctors about Chophytol, then we can conclude that the remedy is effective in chronic cholecystitis and, in addition, works well in disorders of liver function. As a hepatoprotector, the drug is most often used to eliminate the effects of toxic liver damage (including drug damage).
Reviews of Chophytol for toxicosis, as well as the results of a number of studies confirm that after the course of the drug, the symptoms of toxicosis completely cease in about 25% of patients, and another 35-50% (according to different data) the general condition improves noticeably.
The forums also often discuss the appropriateness, safety and efficacy of Chophytol for children (in particular, for newborns). For older children, the medicine is prescribed for the treatment of diseases of the bile duct and gall bladder, as well as for the elimination of dyspeptic symptoms, for newborn children - for the treatment of physiological jaundice.
Most mothers give good reviews about the drug, because it has a natural composition, is well tolerated by children and is easy to use. Nevertheless, there are also some reviews that mention side effects on the background of treatment (the cause of complaints is most often diarrhea), and also that in some cases the medicine did not alleviate the condition of the child at all.
For the sake of justice, it should be noted that negative reviews about Chophytol are single. Mostly they are left by people who are dissatisfied with the fact that the medicine has not relieved them completely of the disease, but only temporarily removed the symptoms.