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Controloc tabs 40mg #14

  • $25.40
  • 3 or more $24.99
  • Availability:In Stock

Controloc user manualYou can buy Controloc hereCompositionBecause the drug may have the form of a powder or tablet, the drug composition will depend on its form of production, the nominal volume.The chemical composition of one tab..

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Controloc user manual

You can buy Controloc here


Because the drug may have the form of a powder or tablet, the drug composition will depend on its form of production, the nominal volume.
The chemical composition of one tablet Controloc coated with special enteric coating may be contained 22.57 mg. or 45.1 mg. active drug substance pantoprazole sodium sesquihydrate.
In addition, in its composition preparation contains auxiliary substances such as purified water, anhydrous sodium carbonate, calcium stearate, mannitol, povidone K90, crospovidone as well.
The composition of the drug shell includes: hypromellose 2910, yellow iron oxide (E172), titanium dioxide (E171), povidone K25, propylene glycol and triethyl citrate, and Eudragit L 30D-55, which is polysorbate 80, sodium lauryl sulfate formed by the reaction of ethyl acrylate copolymer and methacrylic acid.
For application to the marking of tablets, specialized ink brown color which contain soy lecithin, titanium dioxide (E171), polydimethylsiloxane emulsion (Dimethicone 1510), red iron oxide (E172) CL 77491, as well as black and yellow iron oxide (CL 77499 and CL 77492, respectively).
The chemical composition of one bottle of Controloc powder intended for the preparation of the solution contains 45.1 mg. active ingredient pantoprazole sodium sesquihydrate. As auxiliary compounds in the preparation, sodium hydroxide (0.24 mg) and disodium edetate (1 mg) are used.

Form of issue

Controloc are released in the form of tablets that have a biconvex form, as well as a special coating in the form of an enteric coating. The tablet core has an almost transparent white color, and the shell is yellow. Over the drug, brown inks are marked with the indication of the dosage in milligrams "P20" or "P40".
The carton pack can contain 3, 4 or 1 blisters, respectively, for 5 or 7 tablets in each, as well as 1 or 2 blisters of 14 tablets each.
Control powder, intended for the preparation of a solution for internal administration, is a dry substance of white color. Typically, the powdered drug compound is packaged in vials.

pharmachologic effect

The drug has an inhibitory effect on the proton pump.

Pharmacodynamics and pharmacokinetics

Due to the presence in the composition of the preparation of pantoprazole, a compound having the ability to affect gastric secretion, Controloc promotes the inhibition of the proton pump of parietal cells. When pantoprazole hits the acidic medium, the compound passes into its active form and starts the process of inhibiting hydrochloric acid.
It is worth noting that the active drug compound acts on hydrochloric acid at the final stage of its isolation, regardless of the origin of the stimulus. The drug has a positive effect on the basal secretion of gastric juice.
As a result, under the influence of pantoprazole, the level of acidity in the digestive tract decreases, which stimulates an increased production of gastrin. The drug is quickly absorbed by the digestive system and even with a single application it reaches the optimal dose for the treatment of a person's body. With the further administration of Control, the concentration of the active compound in the body does not change and is at a level of 1.5 μg / ml.
It is extremely rare, but a drug compound can provoke an increase in the level of endocrine cells in the stomach. However, this only occurs with prolonged therapeutic treatment with Controloc. It is noteworthy that the pharmacokinetics remain unchanged both for oral administration and for intravenous administration of the drug compound.
The effectiveness of the drug varies depending on the dosage, but on average the antisecretory effect is achieved, as a rule, after a maximum of 4 hours and persists for the next 24 hours. In the treatment of duodenal ulcers caused by a gram-negative bacterium Helicobacter pylori, the drug helps to reduce gastric secretion, and also significantly increases the sensitivity of harmful microorganisms to antibiotics.
Controloc have no effect on the motility of the gastrointestinal tract. Metabolization of the drug compound occurs in the liver, about 80% of pantoprazole is excreted in the kidneys, and 20% is excreted with feces. The intake of the drug with food has no effect on the concentration of the active substance in the body.
Compared to analogous preparations, the Controloc, which has a neutral pH, is the most chemically stable and has the least harmful effect on the liver oxidase system, directly dependent on cytochrome P450. For this reason, the drug does not interact with other proton pump inhibitor drugs.

Indications for use

Controllers are recommended for use in the presence of:
    non-erosive reflux disease (NERD);
    gastroesophageal reflux disease (GERD);
    erosive reflux esophagitis;
    ulcers of the duodenum, as well as of the stomach, including in the phase of exacerbation;
    eradication of Helicobacter pylori;
    erosive gastritis, including those caused by the intake of NSAIDs;
    the Zollinger-Ellison syndrome.
The drug in the form of a powder is used, as a rule, in the treatment and prevention:
    complications caused by an ulcer, for example, with perforation or bleeding;
    stress ulcers.


The drug is not recommended for use with dyspepsia of neurotic genesis, as well as hypersensitivity or individual intolerance of the constituent components of the drug. Controloc are not recommended for use by children under 18 years of age, as well as women during pregnancy and lactation. In addition, the drug is not allowed to be used with Atazanavir.

Side effects

When using Controloc, the following side effects may occur:
    diarrhea or constipation;
    an allergic reaction, expressed in the form of itching and burning, skin rashes, angioedema, Stevens-Johnson and Lyell syndrome, and photosensitivity;
    blurred vision;
    depressive conditions;
    damage to liver cells;
    peripheral edema;
    increased levels of TG, as well as liver enzymes.
The above side effects of the drug occur extremely rarely and disappear, usually after the drug is withdrawn.

Controloc, instructions for use (Method and dosage)

In accordance with the instructions for Controloc, the drug in tableted form is taken orally by washing with a large amount of water. Although the time of ingestion or day does not have a decisive influence on the effectiveness of the drug, to achieve the best result of treatment, doctors are advised to follow a certain schedule of drug intake, which will vary depending on the type of disease and its severity.
For example, with ulcer of the duodenum or stomach, as well as with erosive gastritis Controloc take 80 mg. per day for two weeks. In acute forms of the disease, the drug intake can last from four to eight weeks.
During eradication, the bacterium Helicobacter pylori is taken 2 times a day in the morning and evening before meals, 1 tablet (20 mg.), In combination with 1000 mg. amoxicillin and 500 mg. clarithromycin. In this case, the course of treatment lasts no more than two weeks.
As an anti-relapse agent and in the process of treatment of reflux-esophagitis Controllers take 20-40 mg each. (respectively) per day for four to eight weeks.
In the therapeutic treatment of hypersecretory conditions, as well as Zollinger-Ellison syndrome, the drug is taken at 80 mg. per day. The same dosage of the drug is used in the prevention and treatment of ulcers, the aggravation of which is caused by stress.
In the form of powder Controloc are used in cases of need for intravenous administration of the drug. To prepare the preparation for injections, saline (10 ml.) Is added to the vial with a dry substance. In some cases, besides the physiological solution, atrium chloride is added to the powder, as well as a solution of glucose (5%).
It is important to use the solution for intravenous administration of the drug for no more than 3 hours after preparation. The pH of the solution should be 9.


During the entire period of application of the Controloc, there were no cases of overdose. Controloc are not used for hemodialysis.


When the drug is used in conjunction with drugs whose pH reacts to the gastric environment, for example, ketoconazole or iron, the absorption is reduced above the indicated active compounds. Assign and use Controloc without the risk of complications can be combined with such drugs as:
    Digoxin, Metoprolol, Nifedipine in the presence of diseases of the cardiovascular system;
    oral contraceptives, which include ethinylestradiol and levonorgestrel;
    a group of NSAID medicines, for example, phenazole, Piroxicam or Diclofenac;
    Levothyroxine, Glibenclamide in diseases of the endocrine system;
    Phenytoin and carbamazepine in epilepsy;
    Diazepam in sleep disorders;
    Fenprokumone, Warfarin (indirect anticoagulants);
    Tacrolimus and Ciclosporin in recovery after transplantation.

Terms of sale

To buy Controloc online you don't need a prescription.

Storage conditions

The drug should be stored in an inaccessible place for children at a temperature of up to 25 ° C.
Shelf life - 3 years.

special instructions

Before the immediate start of use of the Controloc in the form of tablets, you should undergo a medical examination and exclude the presence of malignant neoplasms. Use Controloc can prevent timely diagnosis of symptoms of cancer.
The preparation in the form of a powder is recommended for use only in those cases when it is not possible to use Controloc tablets. This medication is not intended for use in the event of mild gastrointestinal complaints.
It is important for elderly patients with impaired renal function to monitor the dosage of the drug.
Patients with severe forms of renal failure should be treated with minimal dosage.
In the course of treatment, Controloc should monitor the level of liver enzymes in patients, so that in case of a sharp increase in their number stop using the drug.
Prior to the use of the drug and after therapy, experts recommend passing an endoscopic control to timely detect the presence of malignant tumors.


The drug is not recommended for people under the age of 18.

During pregnancy (and lactation)

Controllers should not be used during pregnancy and breastfeeding.

Reviews about Controloc

Patients using the drug for the treatment of peptic ulcers, gastritis and other gastrointestinal diseases leave, as a rule, positive feedback about Controloc on the forums. In their opinion, the drug effectively cope with the symptoms of ailments and quickly alleviates the condition, eliminating heartburn, heaviness and abdominal pain, while extremely rarely causing unpleasant side effects.

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