Hepa-Mertz #10

Hepa-Mertz instruction for use

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Composition

One sachet contains 5 g of a mixture of granules for the preparation of a Hepa-Merz solution containing 3 g of ornithine aspartate (active drug compound), as well as the following excipients: E110 (orange yellow dye), orange and lemon flavors, cyclamate sodium, levulose, saccharin and polyvinylpyrrolidone.
In a single ampoule concentrate for the preparation of Hepa-Mertz solution there is 5 g. Ornithine aspartate, as well as up to 10 ml. water for injection (auxiliary connection).

Form of issue

The granulate (a mixture of Hepa-Mertz granules of white and orange colors) for the preparation of the solution is packaged in sachets of 5 g each. One carton contains 30 sachets.
The concentrate is produced in ampoules of dark glass, with a nominal volume of 10 ml. One carton pack contains 10 ampoules.

pharmachologic effect

The drug has a hepatoprotective pharmacological effect on the human body. Hepa-Mertz refers to a hypoazotemic pharmaco-therapeutic group of drugs.

Pharmacodynamics and pharmacokinetics

The active compound ornithine aspartate, contained in Hepa-Mertz, participates in biosynthesis from urea ammonia (the ornithine Krebs cycle), and promotes the production of STH and insulin, speeds up protein metabolism, improves liver function (detoxification effect) and lowers ammonia levels in the blood.
The medicinal substance is quickly absorbed in the stomach and penetrates into the blood through the intestinal epithelium and is excreted from the body with urine.

Indications for use Hepa-merz

Indications for the use of Hepa-Mertz are:
    liver diseases, including chronic or acute forms, accompanied by hyperammonemia;
    hepatic encephalopathy.
As part of complex therapy, the drug is used to treat disorders of consciousness (coma or a state of precoma). In addition, Hepa-Merz acts as a corrective supplement in the diet for patients with protein deficiency.
The drug can be used to remove intoxication during alcohol poisoning.

Contraindications

The drug is contraindicated in cases of impaired renal function (with a blood content of 3 mg / 100 ml of creatine).

Side effects

It should be noted that such possible side effects of the drug as nausea, allergic rashes on the skin and vomiting are extremely rare.

Hepa-Merz, instructions for use (Method and dosage)

In accordance with the instructions for use Hepamerz, the drug is recommended after eating. To prepare a single dose of the drug should be mixed 200 ml. water (better than room temperature) with a single sachet packet containing 5 grams of granulate powder.
The Hep-Merz solution for infusions is administered intravenously at a dose of 20 g (i.e., 4 ampoules of the drug) per day. The recommended average daily therapeutic dose of the drug can be increased to a maximum of 8 ampoules (40 grams) per day.
The drug Hepa-Merz is not released in the form of tablets.

Overdose

Increased side effects of the drug may signal an overdose of Hepa-Merz. In this situation, first of all, stop using this medication. Patients are washed with a stomach, symptomatically treated and activated charcoal.

Interaction

At present, there is no information about the drug interaction of Hepa-Mertz with other drugs.

Terms of sale

Over-the-counter leave from pharmacies.

Storage conditions

Keep out of reach of children at a temperature not exceeding 25 ° C.

Shelf life

5 years.

special instructions

Before direct intravenous administration of Hepa-Merz solution, more than 6 ampoules (500 ml solution for infusion) of the drug should not be dissolved at a time. In order to exclude vomiting and nausea, the rate of administration of the drug should be optimized.
During the use of the drug for the treatment of hepatic encephalopathy patients are advised to refrain from driving vehicles, and not to work with potentially dangerous mechanisms and not engage in activities that require increased concentration of attention, and besides a rapid mental reaction.

In pregnancy and lactation

Although pregnancy does not apply to absolute contraindications to the use of Hepa-Mertz, it is necessary to take the drug during this period only under the supervision of a doctor. It is recommended to stop breastfeeding while taking the medication.

Reviews about Hepa-Mertz

People who took the drug leave in the bulk of the positive feedback on the forums about the drug, noting its effectiveness and a small number of contraindications, as well as side effects. Judging by the reviews about Hepa-Merz, this drug is suitable for a wide range of patients, including children and the elderly.