Hepa-Merz concentrate 10ml 5gr #10
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Hepa-Merz concentrate instruction for useReed more and buy Hepa-Merz concentrate hereForm of release, composition and packagingConcentrate for the preparation of a solution for infusions is transparent, light yellow in color.1 ml ..
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Hepa-Merz concentrate instruction for use
Reed more and buy Hepa-Merz concentrate here
Form of release, composition and packaging
Concentrate for the preparation of a solution for infusions is transparent, light yellow in color.
1 ml of 1 amp.
L-ornithine L-aspartate 500 mg 5 g
Auxiliary substances: water d / and.
10 ml - dark glass ampoules (10) - cardboard boxes.
pharmachologic effect
Hypoammonemic drug. Reduces the elevated level of ammonia in the body, in particular, with liver diseases. The effect of the drug is associated with its participation in the ornithine cycle of urea formation Krebs (formation of urea from ammonia).
Promotes the production of insulin and growth hormone. Improves protein metabolism in diseases requiring parenteral nutrition.
Pharmacokinetics
It is excreted in the urine through a cycle of urea formation.
Indications for Hepa-Merz solution
- acute and chronic liver disease, accompanied by hyperammonemia;
- hepatic encephalopathy, incl. in the complex therapy of mental disorders (precoma and coma);
- as a corrective additive to preparations for parenteral nutrition in patients with protein deficiency.
Contraindications
- renal failure of severe degree (serum creatinine> 3 mg / 1 dl);
- the period of lactation (breastfeeding);
- Hypersensitivity to the components of the drug.
Dosage
In / in injected up to 40 ml (4 amp.) / Day, dissolving the contents of the ampoules in 500 ml infusion solution.
In hepatic encephalopathy (depending on the degree of severity of the condition), IV injection of up to 80 ml (8 amp.) / Day.
Duration of infusion, frequency and duration of treatment are determined individually. The maximum infusion rate is 5 g / h.
It is recommended to dissolve no more than 60 ml (6 amp) of the drug in 500 ml of the infusion solution.
Side effects
From the side of the digestive system: in some cases - nausea, vomiting.
Other: allergic reactions.
Overdose
Symptoms: increased severity of side effects.
Drug Interactions
The drug interaction of the Hepa-Merz drug is not described.
special instructions for Hepa-Merz solution
If there is nausea or vomiting, you should reduce the speed of the drug.
Impact on the ability to drive vehicles and manage mechanisms
With hepatic encephalopathy, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.
Pregnancy and lactemia
The drug should be used with caution in pregnancy.
The drug is contraindicated for use during breastfeeding.
In case of violations of kidney function
The drug is contraindicated in patients with severe renal insufficiency (creatinine score 3 mg / 100 ml).
With violations of liver function
The drug is used according to the indications.
Conditions of leave from pharmacies
To buy solution of Hepa-Merz you don't need a prescription.
Terms and conditions of storage
The drug should be stored out of reach of children at a temperature of no higher than 25 ° C. Shelf life - 5 years.
