Lipoic acid tabs 25mg #50

Lipoic acid instruction for use

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Composition

The tablet contains 12 or 25 mg of active ingredient of thioctic acid. In 1 ampoule, 10 ml of the solution.

Form of issue

Lipoic acid is released in the form of tablets in a special film membrane in a package of 10, 50, 100 pieces.

pharmachologic effect

The active ingredient is an endogenous antioxidant that can bind aggressive free radicals. Alpha-lipoic acid acts as coenzyme in the process of transformation of substances that are pronounced antioxidant effects.
Such substances are able to exhibit protective, protective functions against cells, which in the process of disintegration of foreign exogenous substances (including heavy metals).
The active substance is involved in the mitochondrial metabolism of substances within the cell. By stimulating the utilization of glucose, thioctic acid is able to exhibit synergy to insulin. In patients with diabetes, the level of pyruvic acid concentration in the blood is recorded.
According to the mechanism and nature of the biochemical effect, the active substance is similar to the B vitamins. The active substance has a lipotropic effect, which is manifested in the acceleration of utilization processes with respect to lipids in the hepatic system. Lipoic acid can stimulate the transition of fatty acids from the liver system to various tissues in the body.
For the medicinal product, the nature of the detoxification effect when the salts of heavy metals and other poisonings enter the body. Thioctic acid changes the cholesterol metabolism, improves the general and functional state of the liver.

Pharmacodynamics and pharmacokinetics

Indicators of pharmacokinetics and a description of pharmacodynamics in the medical literature are not found.

Indications, use of lipoic acid

The drug is widely used in the therapy of hepatic pathology, nervous system, alcoholism and intoxication, diabetes mellitus, to facilitate the oncological diseases.
Main indications:
    chronic hepatitis in the active phase;
    chronic pancreatitis against alcoholism;
    chronic cholecystopancreatitis;
    acute hepatic insufficiency;
    intoxication with heavy metals, hypnotic medicines, carbon, carbon tetrachloride, mushrooms;
    viral hepatitis with progressive jaundice;
    hepatic cirrhosis;
    diabetic polyneuritis;
    alcoholic polyneuropathy;
    poisoning with pale toadstool;
    fatty liver hepatic dystrophy;
    dyslipidemia;
    coronary atherosclerosis.
During the course of treatment with Prednisolone, the medication acts as an equalizer and synergist to prevent the development of a "withdrawal syndrome", a smooth decrease in the dose of a glucocorticosteroid.

Lipoic acid for weight loss

The mechanism of action of the active substance makes it possible to use a medicament to get rid of excess weight. The effect is more pronounced with simultaneous active sporting activity. Lipoic acid is capable of triggering the mechanism of fat burning, but it is impossible to burn absolutely all the excess fat by itself, therefore intensive physical loads are required.
Muscle tissue "attracts" nutrients during exercise, and thioctic acid can increase endurance by enhancing fat burning and increasing the overall effectiveness of physical activity. Simultaneous adherence to the diet allows you to achieve the greatest result.

Dosage of lipoic acid for weight loss

Usually, 50 mg of the drug is sufficient. The minimum threshold is 25 mg. The most effective time to take the medicine to achieve maximum results in the fight against excess weight:
    before or immediately after breakfast;
    at the last daily meal;
    after training, physical activity.

Reviews

The drug works well with diet and simultaneous active combination of activities in the gym. At thematic forums, users open a little secret: the drug works best when taking carbohydrate food (manna or buckwheat porridge, dates, honey, pasta, rice, peas, beans, bread products).

Lipoic acid in bodybuilding

Quite often in bodybuilding, thiectic acid is combined with Levocarnitine (Carnitine, L-carnitine). This amino acid is a relative of B vitamins, and is able to activate fat metabolism. Levokarnitin releases fat from cells, stimulating energy consumption.

Contraindications

    breast-feeding;
    allergic responses;
    individual hypersensitivity;
    pregnancy.
The age limit is up to 16 years.

Side effects

    diarrheal syndrome;
    epigastric pain;
    nausea;
    anaphylactic reactions;
    skin rashes;
    vomiting;
    convulsions;
    increased intracranial pressure;
    disorders of glucose metabolism (hypoglycemia);
    a migraine headache;
    hives;
    itching;
    tendency to bleeding (with functional disorders of platelets);
    pinpoint hemorrhages;
    diplopia;
    difficulty breathing.

Lipoic acid, instructions for use (Method and dosage)

Every day 300-600 mg of thioctic acid is injected intravenously, which corresponds to 1-2 ampoules of 10 ml and 1 ampoule with a volume of 20 ml of a concentration of 3%. The duration of therapy is 2-4 weeks, after which the treatment is continued with a tablet form in a daily dose of 300-600 mg.

Instructions for use Lipoic acid in tablets

Inside 30 minutes before eating. Tablets can not be broken and chewed. Daily dose: 1 tablet once a day (300-600 mg). The therapeutic effect is achieved by taking 600 mg per day. In the future, the dose can be reduced by half.
In diseases of the hepatic system, tablets are prescribed: up to 4 times a day for 50 mg per month. The repeated course can be conducted after 1 month.
Therapy of diabetic neuropathy and alcoholic polyneuropathy: begin with intravenous injections with transition to the tablet form at 600 mg per day.

Overdose

The clinical picture consists of the following negative manifestations:
    diarrheal syndrome;
    headache;
    nausea;
    epigastric pain;
    allergic responses;
    anaphylactic shock;
    hypoglycemia.
Treatment posindromnoe.

Interaction

Medication is able to enhance the effects of glucocorticosteroid drugs. There is a suppression of cisplatin activity. The drug enhances the effect of hypoglycemic agents (oral forms), insulin.
It is not recommended to use with medicines that contain metal ions (calcium, magnesium, iron) because of the ability of Lipoic acid to bind metals.
If there is an acute need for the use of drugs, it is recommended to maintain a certain time interval (minimum 2 hours). Metabolites of ethanol and he weakens the action of thiectic acid.

Storage conditions

Transportation and storage of tablets and solution is allowed only if the temperature regime is observed - up to 25 degrees.
Shelf life - 3 years.

special instructions

The main ways of metabolism are oxidation and conjugation (source - Wikipedia).

Benefit and harm

Lipoic acid refers to natural antioxidants and vitamins. It helps normalize and accelerate metabolic processes, stimulates the pancreas, removes toxins from the body, lowers blood sugar levels, improves visual perception, beneficially affects the heart, reduces cholesterol, and helps normalize blood pressure.
Against the background of Lipoic acid, there is a decrease in the severity of negative reactions that occur after chemotherapy in cancer patients.
The drug has a beneficial effect on the state of nerve endings that are damaged as a result of diabetes mellitus. Rarely on the background of the use of medicament negative reactions are manifested.

Children

Thioctic acid in pediatric practice can be used from 16 years.

In pregnancy and lactation

Lipoic acid is not used in pregnancy.
Breastfeeding is also a contraindication.

Reviews about lipoic acid

The medication is well tolerated, and has proved to be an effective drug for intoxication, poisoning, liver system diseases.

Reviews about lipoic acid with losing weight

There are a lot of different opinions. Someone did not feel any effect at all, retaining their weight, despite the regular use of the medication. Some users note that taking Lipoic acid in combination with intensive cardioads and observing a certain diet, allows you to significantly reduce weight, without harming your health.
Patients suffering from diabetes, note that the drug can reduce the severity of adverse reactions of hypoglycemic agents (in some cases it was possible to reduce dosage) and improve overall health.