Micrasim caps 25000 #50

Micrasim instruction for use

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Composition

The composition contains active substance pancreatin in microgranules, soluble in the intestine.
As additional substances in the preparation contains: triethyl citrate, eudragit (butyl methacrylate, methyl methacrylate and dimethylaminoethyl methacrylate copolymer), simethicone emulsion, gelatin, talc, H2O, methyl parahydroxybenzoate, sodium lauryl sulfate, propylparaben, dyes, Titanium Dioxide.

Form of issue

Micrasim is available in capsules. Gelatine hard capsules have a brown lid and a transparent body. Inside the capsules there are spherical or cylindrical pellets of brown or light brown color. They have a characteristic smell.
Both capsules of 10,000 units and capsules of 25,000 units are contained in blisters of 10, 20, 30 pieces.

pharmachologic effect

Micrasim is a drug related to the last generation of enzymatic agents. It contains the active ingredient pancreatin. This is a complex of digestive enzymes that are involved in the process of digesting food. The composition of pancreatin contains amylase, lipase, protease. These enzymes of the pancreas promote the process of assimilation in the body of carbohydrates, fats, proteins. The capsule contains granules of pancreatin, which look like minimocrosses, which are gastro-resistant. This effect is provided by a special coating, preventing the effect of gastric acid on the contents. Consequently, the enzymes of the drug are involved in digestion during the passage through the intestine of food, at the level of the stomach for these processes it does not affect.
Pharmacokinetics and pharmacodynamics
Enzymes are released in the small intestine and promote active digestion of food, normalization of these processes. After ingestion for several minutes, the capsule dissolves in the stomach, and the minimacrospheres of pancreatin are released. The effect after ingestion of the capsules is observed after about 30-40 minutes. Only local effects of the drug are noted, in the intestine it is not absorbed. It is excreted with feces.

Indications for use

It is advisable to take Micrasim in the following cases:
    As a substitution treatment for patients with pancreatic insufficiency (with chronic inflammations in the pancreas, cystic fibrosis, pancreatic tumors, after removal of the gland).
    For symptomatic treatment of digestive disorders (gastritis with reduced acidity in chronic form, functional dyspepsia, biliary tract and liver diseases, and diseases of the large or small intestines, in which the evacuation function is disrupted after removal of the gallbladder, stomach, intestine).
    In order to ensure the greatest activity of the digestion process with sufficient function of the digestive tract (overeating, eating very fatty foods, malfunctioning chewing, prolonged immobilization).
    In the process of complex preparation for ultrasound or X-ray examination of the abdominal cavity.

Contraindications

Do not take the drug if the patient notes:
    intolerance to pancreatin or its components;
    inflammatory phenomena of the acute form in the pancreas;
    stage exacerbation of chronic changes in the pancreas.

Side effects

In most cases, patients tolerate this remedy well, but sometimes there are some side effects. In this case, the drug should be canceled or adjusted its dose.
Possible side effects (most often they develop when the dosage is exceeded):
    allergic reactions on the skin in the form of rashes, hives;
    constipation;
    diarrhea;
    discomfort in epigastrium;
    nausea and vomiting;
    elevated uric acid levels in urine and blood.
There were rare cases of narrowing of the intestinal lumen in patients with cystic fibrosis.

Micrasim, instructions for use (Method and dosage)

As indicated in the instructions for use, Micrasim 10000 should be taken during food or after eating. The capsule should be washed with plenty of liquid. You can not chew capsules. If necessary, the contents of the granule can be mixed with food or liquid. Such a mixture must be swallowed without chewing.
Cystic fibrosis in children up to the age of 4 years is indicated for each kilogram of weight of 1000 units of lipase. After four years of age, children should receive 500 units of lipase per kilogram of body weight. The maximum permissible dose is 10,000 U / kg for 24 hours.
With diarrhea and steatorrhea, with each meal, 25,000 units should be taken. The maximum allowable dose is 35,000 U with one meal.
The maximum permissible dose for children under 1.5 years is 50000 units of lipase per day. Those children who are already 1.5 years old can take no more than 100,000 units of lipase per day.

Overdose

If the dosage was significantly exceeded, there may be a tendency for constipation in children, as well as hyperuricosuria and hyperuricemia. With such symptoms, it is necessary to cancel the medicine, consume a lot of fluid and perform symptomatic treatment.

Interaction

When taking Micrasim, absorption of folic acid and iron can decrease. Bioavailability of the drug is reduced if Micrasim is taken concomitantly with antacids, which contain calcium carbonate or magnesium hydroxide.

Terms of sale

You can buy Micrasim without a prescription.

Storage conditions

Keep the capsules in the original packaging, at a temperature not higher than 25 degrees.
Shelf life - for 2 years.

special instructions

It is necessary to clearly monitor the patient's state of health during long-term admission of Micrasim.
There is a decrease in the pharmacological effectiveness of the drug in dysbiosis, acidification of the contents of the small intestine, helminthic invasions, duodenosis. Also, the effectiveness of the drug is reduced if the drug is taken after the expiration date has expired.
If the drug is stored at high temperature, then the activity of minimocrosses decreases relatively quickly.
On the ability to focus, work with precise mechanisms, drive a car, taking medication is not affected.
When treating with Micrasim need to drink plenty of fluids. Do not drink capsules with alkaline liquids.

Children

It is used to treat children in the appropriate dosage and only after appointment of a specialist.

In pregnancy and lactation

During pregnancy, the remedy can be used if the benefit of treatment exceeds the likely risk. There is no data on the penetration of pancreatin into breast milk. During lactation, this remedy can be used only after the appointment of a doctor.

Reviews about Micrasim

Comments on Micrasim are often left by those who noted a marked improvement when using this medication. It is noted that this tool helps not only with diseases of the pancreas and digestive organs, but also allows you to effectively overcome unpleasant symptoms during overeating. The doctors' testimonies testify that Micrasim should be used according to the indications, as his uncontrolled reception may not bring the expected effect.