Panzinorm forte 20000 #30

Instruction for Panzinorm forte

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The preparation Panzinorm forte 20000 represents an enzyme failure, used in gastroenterology to reduce the load on the pancreas and improve the digestive process.

Form of formulation and composition of the preparation

Panzinorm forte 20000 is available in the form of tablets coated with an enteric coating of white or slightly grayish color with a characteristic smell of vanilla. Tablets are packed in blisters of 10 pieces for 1 or 3 blisters in a cardboard bundle with the attached instructions.
The composition of 1 tablet includes pancreatin, which is equated to the active ingredients:
    Amylase;
    Lipase;
    Protease.
As auxiliary components are lactose monohydrate, microcrystalline cellulose, colloidal silicon dioxide, magnesium stearate.

pharmachologic effect

The drug Panzinorm forte 20000 belongs to the group of enzyme agents. Compensates the insufficiency of the secretory function of the external ducts of the pancreas, the therapeutic effect is due to the active ingredients in the tablet.
The lipase, included in the preparation by hydrolysis, cleaves fats into acids, glycerol, which facilitates the absorption of fat-soluble vitamins from food. Amylase promotes the rapid breakdown of carbohydrates to sugars, the protease cleaves proteins, which speeds up the process of their assimilation by the body.
After taking the pill inside the therapeutic effect of the drug begins only in the small intestine, where the protective coating of the drug is cleaved. The enzymes included in the preparation accelerate and facilitate the process of digestion, so that useful substances, proteins and vitamins are completely absorbed by the intestinal walls from incoming food.
The drug eliminates symptoms such as bloating, flatulence, a feeling of heaviness after eating, nausea, caused by a lack of enzymes in the body.

Indications for use

Tablets Panzinorm forte 20000 is prescribed for adults and children for the treatment and prevention of the following conditions:
    Chronic pancreatitis with pronounced insufficiency of the exocrine function of the pancreas;
    Cystic fibrosis;
    Inflammatory diseases of the duodenum, stomach, gall bladder, as a result of which the process of digestion of food is disrupted;
    Disorders of the small intestine, as a result of which the process of cleavage of proteins, fats and carbohydrates is disrupted;
    Postponed operations on the digestive organs;
    Resection of the stomach or pancreas;
    Improving the process of digesting food after a plentiful feast or inaccuracies in the diet;
    A sedentary lifestyle, excess weight, as a result of which the process of digestion can be disturbed;
    Preparation for X-ray examination or ultrasound of the abdominal cavity.

Contraindications to use

The drug has a number of contraindications, so before starting therapy, you should carefully read the attached instructions. Tablets Panzinorm forte 20000 can not be taken in the following cases:
    Acute pancreatic inflammation or exacerbation of chronic pancreatitis;
    Age at children till 3 years for the given medicinal form;
    Patients with cystic fibrosis younger than 15 years (for tablets at this dosage);
    Individual hypersensitivity to the components of the drug;
    Intolerance of pork protein.
With caution this medication is used to treat pregnant women.

Dosing and Administration

Tablets Panzinorm Я forte 20000 are intended for oral use. Tablets can not be chewed and crushed, it is recommended to swallow immediately, washing down with a small amount of water.
The drug is taken with food, with the dose and duration of treatment determined by the doctor individually.
According to the instructions Panzinorm forte tablets 20000 appoint 1 piece 3 times a day during meals. If necessary, according to the indications, the dose of the drug can be increased with the permission of the doctor.
In case the drug is prescribed in preparation for X-ray or ultrasound examinations, it is enough to take 2 tablets on the evening of the day before and 2 tablets in the morning before the procedure.
In pediatric practice, the dose for children older than 3 years is calculated on an individual basis. The course of therapy of the drug can be from several days to several weeks or even months, depending on the severity of the disorders.

Use among pregnant women and nursing mothers

The use of Panzinorm Fort tablets during pregnancy is limited, so treatment with the drug is only possible if the benefit for the expectant mother is greater than the potential risks to the fetus. In the course of the studies, the teratogenic or embryotoxic effect of the drug on fetal development in the womb was not established.
Ingredients of the preparation can penetrate into breast milk, so before beginning therapy with pills, the nursing mother should consult a doctor.

Adverse Events

The drug is well tolerated by patients. Side effects occur only in rare cases with individual hypersensitivity or exceeding the recommended dose. Adverse reactions are manifested by the following symptoms:
    Hyperemia of the skin;
    Pain in the stomach, hunger;
    Rumbling in the abdomen, flatulence;
    Diarrhea;
    Rashes on the skin.
In rare cases, the patient may develop hyperuricemia and hyperglycosuria.

An overdose of the drug

When using the drug for a long time in large doses, the patient may develop signs of overdose:
    Nausea, vomiting, diarrhea;
    Change in the indicators of urine analysis - increase in glucose level, hyperuricemia;
    Skin irritation around the anus;
    Development of strictures in patients with cystic fibrosis.
When developing signs of an overdose, the patient should immediately stop treatment with the drug and consult a doctor. Patients in this case are symptomatic therapy.

Interaction with other drugs

The drug Panzinorm forte is not recommended at the same time to appoint with folic acid or iron preparations, as with this drug interaction, the process of absorption of the latter in the small intestine is disrupted.
The enteric membrane begins to dissolve in the duodenum, therefore, it is not recommended to administer Panzinorm forte to patients simultaneously with drugs that reduce acidity. Antacids and enveloping agents significantly reduce the effectiveness of Panzinorm Fort.

special instructions

In the case of complex treatment of cystic fibrosis, when the recommended dose of Panzinorm Fort is exceeded in patients, the risk of developing strictures (fibrous colonopathy) in the ascending colon is increasing.
The drug does not have a negative effect on the central nervous system and does not inhibit the rate of psychomotor reactions.

Drug analogues

The following medicines are similar in their effect with the preparation Panzinorm forte 20000:
    Pancreatin tablets;
    Kreon capsules;
    Mezim forte;
    Festal tablets;
Before replacing the prescribed drug with its analogue, the patient should always check with the doctor about the dose.

Leave and storage conditions

Tablets Panzinorm forte 20000 can be bought in a pharmacy without a doctor's prescription. Store the drug in a dry cool dark place in the original package. Ensure that the product is not accidentally taken by children.
Shelf life of the tablets is 2 years from the date of production, which is indicated on the package. Tablets with expired shelf life should not be taken orally.