Motilak tabs 10mg #30
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Instruction for MotilakReed more and buy Motilak onlineCompositionOne tablet in the shell contains 10 mg of domperidone and additional substances: aerosil, lactose, sodium carboxymethyl starch, PVP, microcrystalline cellulose, sta..
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Instruction for Motilak
Reed more and buy Motilak online
Composition
One tablet in the shell contains 10 mg of domperidone and additional substances: aerosil, lactose, sodium carboxymethyl starch, PVP, microcrystalline cellulose, starch, silicon dioxide, polysorbate-80, titanium dioxide.
In one tablet for resorption contains 10 mg of domperidone and additional components: magnesium stearate, FS-95 adjuvant, glucose, starch, carboxymethyl starch and flavor (mint natural oil).
Form of issue
The medication is available in tablet form: tablets for resorption and tablets covered with a special coating. In each cardboard pack there are 30 tablets (3 blisters for 10 pieces).
pharmachologic effect
By its structure, the active ingredient domperidone is similar to neuroleptics, and in terms of effectiveness it is comparable with metoclopramide. The active substance has no practical effect on the severity of gastric secretion and is not capable of causing extrapyramidal disorders.
By increasing the time of contraction of the walls of the duodenum and stomach, the drug has a positive effect on the peristalsis of the gastrointestinal tract. The drug accelerates the emptying of the stomach, without delaying the food lump.
Due to increased tone of the gastroesophageal sphincter, an antiemetic effect is achieved.
Pharmacodynamics and pharmacokinetics
The active substance is absorbed rapidly after ingestion. Biological availability is about 15% (low). With a decreased acidity of the gastric juice, the absorption of the active ingredient decreases. The peak concentration is recorded after 60 minutes. The connection with plasma proteins is 93%.
The drug penetrates all tissues of the body, a small concentration is recorded in the brain. In the liver, the walls of the intestine are subjected to intensive metabolism. The half-life is 7-9 hours.
Indications for use of Motilak
What is the drug Motilak? The medication is actively prescribed when:
reflux-esophagitis;
eructation;
heartburn.
From what tablets domperidona can be appointed:
enhanced gassing;
pain in epigastrium.
Indications for use in patients with Parkinson's disease: nausea on the background of taking Levodopa and Bromocriptine.
Contraindications
Medication is not prescribed when:
bleeding in the digestive tract;
individual hypersensitivity to domperidone derivatives;
mechanical obstruction of the gastrointestinal tract;
perforation in the digestive system;
diagnosis of prolactinoma.
Side effects
skin rashes;
gynecomastia;
extrapyramidal disorders (in pediatrics);
spasms of the intestine;
anaphylaxis;
hives.
Instructions for use Motilak (Method and dosage)
How to prescribe the drug Motilak?
Instructions for use: daily dose - 30 mg; single dose - 10 mg. It is recommended to take the medicine 30 minutes before meals. Tablets for resorption should be kept in the mouth until completely dissolved; tablets in the shell can not be broken, divided and chewed. In single cases, the daily amount of the drug can be increased to 60 mg.
Children (weight 20-30 kg) are prescribed for ½ tablets 2 times a day. At weight over 30 kg appoint 1 tablet twice a day.
Overdose
Extrapyramidal disorders, increased drowsiness, disorientation in space and time are recorded. It is recommended the appointment of enterosorbents (activated charcoal), timely gastric lavage, the appointment of post-syndrome therapy.
Antihistamines help to stop extrapyramidal disorders.
Interaction
Antisecretory agents and antacids can have a negative effect on the bioavailability of Motilak.
M-holinoblokatory reduces the ability of the drug in relation to the evacuation of the stomach and intestines.
Inhibitors of HIV protease, nefazodone, macrolides and azole agents increase the level of domperidone in the blood.
Terms of sale
To buy Motilak you don't need a prescription.
Storage conditions
Protect from moisture. The temperature regime recommended by the manufacturer is not more than 25 degrees.
Shelf life - 2 years.
special instructions
If simultaneous therapy with antacids is required, it is recommended to maintain a 30-minute interval between medications.
What is better Motilium or Motilak?
There is no unequivocal answer. The active ingredient in the preparations is domperidone, the difference is only in the manufacturers of medicines.
In pregnancy and lactation
With care, providing for possible risks.
Reviews about Motilak (general view)
The drug is well tolerated and effectively copes with eructations, heartburn, and swelling.
Reviews about Motilak in pediatrics: the rapid action of the drug allows you to timely stop the attacks of epigastric pain in children.