Alfa-Tocopherol Acetate solution 30% 50ml

Alfa-Tocopherol Acetate instruction

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Composition

The drug contains Alfa-Tocopherol acetate (vitamin E). A solution in the form of a solution for internal use also includes sunflower refined oil as an additional component.

Form of issue

Capsules and oil solution of tocopherol acetate 30% for oral administration.

pharmachologic effect

The medicine serves to fill the lack of vitamin E in the body. Antioxidant.

Pharmacodynamics and pharmacokinetics

Alfa-Tocopherol acetate (vitamin E) is involved in tissue metabolism. This remedy prevents hemolysis of red blood cells and the appearance of peroxides, which can damage cellular and subcellular membranes. Prevents free radical reactions, the appearance of degenerative-dystrophic changes in skeletal muscles and heart muscle, atherosclerosis, disruption of the testicles and seminiferous tubules, as well as the placenta. In addition, it prevents an increase in the permeability and fragility of capillaries, improves reproductive function. Normalizes nutrition and contractility of the myocardium, tissue respiration. Reduces myocardial oxygen consumption. Helps in the synthesis of gem and heme-containing enzymes, as well as in the synthesis of proteins. Protects vitamin A from oxidation. Prevents the oxidation of selenium and unsaturated fatty acids. It blocks the synthesis of cholesterol.
Tocopherol acetate for the face with regular application allows you to achieve the following results:
    retardation of aging - the skin lasts longer and tighter and firmer, without wrinkles;
    healing of damaged areas - wounds heal much faster;
    the prevention of oncological diseases;
    improving the protection of skin from ultraviolet rays - redness, burns and other reactions that can be provoked by sunlight, appear less often;
    normalization of the skin - tocopherol prevents peeling, reduces the fat content of the skin and helps to control the work of the sebaceous glands, it also saturates the cells with oxygen, promotes regeneration. The skin has a healthier and more attractive appearance without surgical interventions.
The drug after oral administration is slowly absorbed by approximately 50%. The maximum concentration in the blood is observed after 4 hours. For absorption, bile acids are needed. With the absorption, a complex is created with lipoproteins - intracellular carriers of tocopherol.
The active ingredient first enters the lymph, and then into the total bloodstream, which is mainly associated with Alfa1 and beta-lipoproteins and, in part, with serum albumin. It accumulates in the adrenal glands, testes, muscle tissue, liver, pituitary gland, lipid tissue, erythrocytes. Splits and is excreted from the body mainly with bile. Some of the drug is excreted in the urine.

Indications for use

This drug is used for hypovitaminosis, severe physical exertion, diseases of the ligamentous apparatus and muscles, states of convalescence after diseases with febrile syndrome, in old age. In addition, it helps in case of menopausal vegetative disorders, asthenic neurasthenic syndrome, posttraumatic myopathy, neurasthenia in overfatigue, primary muscular dystrophy, postinfection secondary myopathy, degenerative and proliferative changes in the joints and ligamentous apparatus of the spine.

Contraindications

The drug can not be used with increased sensitivity to its components, myocardial infarction, cardiosclerosis.
With caution, it should be used in the case of hypoprothrombinemia.

Side effects

With the use of this tool, allergic reactions, diarrhea, epigastric pains are possible. In the case of intramuscular injection - infiltration at the injection site, tenderness.

Instructions for use Tocopherol acetate (Method and dosage)

The usual dosage is 100-300 mg daily. If necessary, it can be increased to 1 g per day.
Instructions for use Tocopherol acetate reports that the exact dose and duration of the course are selected depending on the purpose of admission:
    for prophylaxis take every day for 100 mg 1-2 times, the course lasts 1-3 weeks;
    violation of spermatogenesis - take 100-300 mg every day as a component of hormone therapy, the course is designed for a month;
    violation of the menstrual cycle - after a day should take 300-400 mg. It should begin with the 17th day of the cycle and for five cycles;
    climacteric vegetative disorders - 100 mg 3 times / day;
    anemia - 200 mg per day;
    hypertension due to pregnancy - 100 mg in I trimester every day or every other day;
    liver disease with periods of exacerbation - take 300 mg per day for several months;
    diseases of the neuromuscular system - taken daily for 100 mg, treatment lasts 1-2 months, the course can be repeated after 2-3 months;
    problems with the menstrual cycle in adolescence before hormonal therapy - take 1-2 times a day for 100 mg, treatment lasts 2-3 months;
    threat of termination of pregnancy - taken daily or every other day for 100 mg in the first trimester;
    neurasthenia due to overwork - take daily 100 mg, treatment lasts 1-2 months;
    Diseases of the skin - 100 mg per day for 20-40 days.

Overdose

When an overdose of a medicine, creatinuria, a decrease in working capacity, pain in the epigastrium are possible. The agent is canceled, glucocorticoids are administered and symptomatic treatment is performed. There is no specific antidote.

Interaction

Combination with Warfarin and Dicumarol may lead to a change in their effect. Possible a decrease in the effectiveness of drugs with iron. The use of ciclosporin increases its absorption.

Storage conditions

Keep the drug in a dark place, the optimum temperature is 18-20 ° C. Keep away from children.
Shelf life - Two years.

Alfa-Tocopherol acetate - Reviews

About Tocopherol, what it is and how to take it, often try to learn on the Internet. This tool is recommended not only by specialists, but also by those who have already tried it on themselves. Negative opinions about him you will not meet. Everyone calls an effective Alfa-Tocopherol acetate - reviews it receives exceptionally positive. Especially often they are left by women who took the drug for the normalization of the menstrual cycle or during pregnancy. They note that it is much more affordable than analogues with vitamin E.