Berocca plus tabs #30

Instruction for Berocca plus

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Composition Berocca Plus

The composition of 1 effervescent tablet of the Berocca plus multivitamin complex includes 500 mg of ascorbic acid (vitamin C), 15 mg of thiamine (vitamin B1), 15 mg of riboflavin (vitamin B2), 23 mg of pantothenic acid (vitamin B5), 10 mg of pyridoxine hydrochloride B6), 40 mg of folic acid (vitamin B9), 10 mg of cyanocobalamin (vitamin B12), 50 mg of nicotinamide (vitamin B3), 15 mg of biotin (vitamin B8), 100 mg of calcium, 100 mg of magnesium and 10 mg of zinc.
The basic composition of vitamins is supplemented with citric acid anhydrous, sodium hydrogencarbonate, sodium carbonate anhydrous, sodium chloride, acesulfame potassium, aspartame, mannitol, polysorbate 60, beta-carotene (E160a), dye red beet (E162) and orange flavor.

Form of issue

The multivitamin complex Berocca Plus is available in the form of effervescent tablets that have a flat cylindrical shape and a pale orange color with patches. Tablets, when dissolved in water, emit bubbles and form a solution of orange color with an orange smell.
Effervescent tablets can be packed in 10 or 15 pieces in aluminum and polypropylene cylinders. In turn, the cylinders are placed on 1, 2 or 3 pieces in cardboard packs. In each pack must be present instructions for the application of Berocca Plus.

pharmachologic effect

Vitamins Berocca Plus is a combined preparation, therefore its pharmacological action is determined by included in its composition vitamins and microelements.
Vitamins of group B take an active part in such an important metabolic process as the synthesis of neurotransmitters.
Vitamin C (ascorbic acid) is a biological antioxidant that plays a key role in the process of inactivation of free radicals, and also significantly increases iron absorption in the small intestine and affects the functions of leukocytes and the metabolism of folic acid. Also ascorbic acid promotes the formation of bone and connective tissue and the normalization of capillary permeability.
Calcium is involved in virtually all not only physiological processes, but also enzyme systems. An important role of calcium along with magnesium and vitamin B6 plays in the transmission of nerve impulses.
Magnesium affects the synthesis of protein and promotes the metabolism of fatty acids and the oxidation of sugars.
Zinc acts as a catalyst when about 300 enzymes are activated. Zinc is a component of many proteins, some hormones, as well as neuropeptides and hormone receptors. But the main function of zinc is still the synthesis of derivatives of vitamin B6 (coenzymes).
Berocca Plus contains the entire complex of active substances that must be taken in therapeutic doses under conditions that are accompanied by an increase in the need for vitamins. Particular attention to this multivitamin complex should be addressed to people who have been subjected to increased physical exertion or for a long period of time were in a state of severe nerve strain.
It is recommended to take this medication and people who sit on restrictive diets, since their food is defective or unbalanced. Well-established vitamins and among the elderly, as well as among those who are being treated for chronic alcoholism and nicotine addiction. Women who constantly take oral contraceptives should also pay attention to these effervescent tablets.

Pharmacodynamics and pharmacokinetics

To date, data on the pharmacokinetics and pharmacodynamics of Berocca Plus is not available.

Indications for use

It is recommended to take effervescent tablets Berocca Plus:
    with a deficiency or condition, accompanied by an increased need for substances such as B vitamins, vitamin C and zinc.

Contraindications

It is not recommended to take the drug Berocca Plus:
    with hypercalcemia;
    with hypermagnesia;
    with urolithiasis (nephrolithiasis, urilolitase);
    with hemochromatosis;
    with hyperoxaluria;
    if the kidney function is impaired;
    with deficiency of glucose-6-phosphate dehydrogenase;
    in children under 15;
    with increased sensitivity to the components of the drug.
With special care for the reception of effervescent Berocca Plus tablets, it is necessary to treat patients with such diseases as atrophic gastritis, vitamin B12 malnutrition, congenital deficiency of the internal factor of Kastla. Also, it is recommended that patients who suffer from intestinal and pancreatic diseases are advised not to take this medication.

Side effects

When taking a multivitamin complex Berocca Plus patients can use discomfort:

From the digestive system:

from mild transient gastrointestinal disorders.

Allergic reactions:

from urticaria, rash, edema of the larynx.

On the part of the hematopoiesis system:

from hemolytic anemia (in people with deficiency of glucose-6-phosphate dehydrogenase).

Berocca vitamins, instructions for use

Before taking the medication, the effervescent tablet must first be dissolved in a glass of water.
The recommended dose for adults and children over 14 years is 1 tablet per day. This daily dose should not be exceeded.
The duration of treatment with this drug is 1 month. If necessary, you can conduct a second course of treatment, but this issue must necessarily be agreed with the attending physician.

Overdose

To date, there have been no cases of an overdose of Berocca Plus.
In overdose, patients may experience discomfort from gastrointestinal disorders (diarrhea and discomfort in the stomach). Note that with excessive intake of vitamin B6, the patient may experience symptoms of neuropathy.
As a treatment, the patient is recommended to completely stop taking the medication and always consult a doctor for symptomatic therapy.

Interaction

When taking pyridoxine (Vitamin B6) at a dose of more than 5 mg, the process of neutralizing the action of levodopa in patients who suffer from such an ailment as parkinsonism may begin.
Such substances as thiosemicarbazone and 5-fluorouracil neutralize vitamin B1.
From the use of antacids it is also better to refuse, since they inhibit the process of resorption of vitamin B1.
Reducing the absorption of vitamin B12 can trigger substances such as neomycin and aminosalicylic acid.
The joint administration of histamine H2 receptor blockers causes the same effect.
A significant decrease in the content of vitamin B12, folic and ascorbic acid, as well as pyridoxine in the serum can be caused by regular intake of oral contraceptives.
Absorption of ascorbic acid may decrease approximately on the simultaneous intake of acetylsalicylic acid and Berocca Plus.
Refuse to take this medication is also recommended for people who take deferoxamine and vitamin C every day (500 mg), since such a combination can adversely affect the condition of the left ventricle.

Terms of sale

Drug Berocca Plus is dispensed from pharmacies without a prescription.

Storage conditions

This multivitamin complex should be stored out of the reach of children. Pay attention to the fact that the packaging is always tightly closed. Temperature regime for storage: 20 - 25 ° C.
Shelf life - 2 years.

Analogues

The main analogues of the drug are Duovit and Supradin, but Berocca Plus analogues such as Revalid is also popular.

Reviews about Berocca Plus

The average Berocca Plus score on the forums is 4.3 on a 5-point scale.

To the advantages of this vitamin complex, forum visitors include:

    the effectiveness of physical and mental stress;
    helps easier to transfer strict diets;
    is issued in effervescent form.

Disadvantages of the drug forum visitors believe:

    high price;
    low efficiency.
After analyzing the reviews on Berocca vitamins, it is worth noting that Berocca Plus vitamins are often compared with suprastin vitamins, but there is no definitive answer to the question "Supradin or Berocca: what is better?" Nevertheless, doctors are more likely to prescribe Supradin during physical and mental overstrain.