Duovit drajee #40

Duovit instruction

You can buy Duovit online

Composition of Duovit

In the composition of Duovit red vitamins are (1 dragee):
    acetate α-tocopherol (vitamin E) - 10 mg;
    palmitate retinol (vitamin A) - 2.94 mg;
    cyanocobalamin (vitamin B12) - 3 mcg;
    ascorbic acid (vitamin C) - 60 mg;
    Thiamine mononitrate (vitamin B1) - 1 mg;
    colcalciferol (vitamin D3) - 200 μg;
    calcium pantothenate (vitamin B5) - 5 mg;
    folic acid - 400 mcg;
    riboflavin (vitamin B2) - 1.2 mg;
    pyridoxine hydrochloride (vitamin B6) - 2 mg;
    nicotinamide (vitamin PP) - 13 mg.

The composition of a blue colored dragee includes:

    calcium hydrogen phosphate dihydrate is 64.5 mg (this corresponds to 15 mg of calcium and 12 mg of phosphorus);
    magnesium lactate dihydrate - 200 mg (this corresponds to 20 mg of magnesium);
    fumarate of iron - 30.3 mg (this corresponds to 10 mg of iron);
    copper sulfate pentahydrate - 4 mg (this corresponds to 1 mg of copper);
    zinc sulfate heptahydrate - 13.3 mg (this corresponds to 3 mg of zinc);
    manganese sulfate monohydrate - 3.1 mg (this corresponds to 1 mg of manganese);
    sodium molybdate dihydrate is 220 μg (this corresponds to 100 μg molybdenum).
Excipients: lactose monohydrate, polysorbate 80, orange oil, glycerol, castor oil, liquid dextrose, povidone, antifoaming agent 1510, sorbitol, magnesium stearate, liquid paraffin, dyes (Opalux, indigo carmine Blue and sunset yellow sunset), emulsion wax, sucrose.

Form of issue

It is produced in the form of pills, 10 pieces (5 red dragees and 5 blue pellets) in a blister, four such blisters in a paper package.

pharmachologic effect

Replenishment of micronutrient deficiencies and vitamins.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

B vitamins are involved in the processes of protein, carbohydrate and fat metabolism, are irreplaceable for the proper functioning of the nervous system. Retinol is indispensable for the development of epithelial cells and for the production of visual pigment. Vitamin D is responsible for absorption of calcium and mineralization of bone tissue. Ascorbic acid is responsible for iron absorption and is a necessary component of oxidation-reduction reactions in the body. Vitamin E is a powerful antioxidant and a membrane protector.
Oligoelements and minerals are also extremely important. Calcium ions are involved in the regulation of the tone of the cardiac muscle and in the processes of the appearance of nerve impulses. And phosphorus and calcium are the necessary elements of bones and teeth. Copper and iron structural components of erythrocytes. Magnesium, zinc, manganese and molybdenum are constituents of a number of important enzymes.

Pharmacokinetics

Water-soluble vitamins (group B, ascorbic acid and biotin) are perfectly absorbed within the daily requirement. The remaining amount is excreted in urine and feces.
After intake, lipophilic vitamins A and D are absorbed in the presence of fats in the small intestine. Absorption of alpha-tocopherol is from 25% to 80% of the dose. These vitamins in a significant amount accumulate in the liver, because of this being potentially toxic.

Indications for use

Duovit vitamins are recommended for:
    active leisure and sports;
    mental and physical overload;
    poor nutrition (elderly people, smokers suffering from alcoholism);
    unbalanced nutrition (dry food, fast food);
    diets for weight loss;
    pregnancy and lactation;
    seasonal shortage of vegetables and fruits in the diet;
    severe loss of mineral substances (excessive menstruation, vomiting, diarrhea, increased sweating).

Contraindications

    Allergy to drug components, hypervitaminosis A, E or D, renal failure.
    Nephrolithiasis, hyperuricemia, gout, erythrocytosis, erythremia, fructose intolerance, thromboembolism, thrombophlebitis, glucose-galactose malabsorption syndrome, impaired metabolism of copper or iron, chronic gromerulonephritis, history of sarcoidosis, hypercalciuria, hypercalcemia, thyrotoxicosis, gastric or duodenal ulcer, tuberculosis in active form.
    Age is less than 10 years.

Side effects

    On the part of immunity: allergic reactions, including anaphylactic shock, Quincke's edema, bronchospasm.
    From the side of metabolism: hypercalcemia.
    From the nervous system: headache, drowsiness.
    From the viewpoint: visual disturbances.
    On the part of the digestive system: nausea, dyspepsia, vomiting, diarrhea, abdominal pain, constipation, increased acidity.
    From the skin: urticaria, rash, skin hyperemia.
    From the excretory system: hypercalciuria.
    General disorders: hyperthermia, sweating.
With long-term admission in large doses occur: hyperuricemia, hyperglycemia, paresthesia, arrhythmia, irritation of the mucosa of the digestive tract, dryness of the palms and feet, alopecia, seborrhea rash, renal damage, temporary increase in LDH, AST, alkaline phosphatase.

Instructions for use Duovit

This section indicates how to take Duovit correctly. If you take vitamins, as prescribed below, they do not cause unwanted effects.
Instructions for Duovit recommend taking vitamins orally in the morning after a meal. Swallow whole, wash with water.
For children from 10 years and adults -1 red dragées and 1 blue pellet per day. The course of therapy is 20 days (can be repeated on the recommendation of the attending physician).

Overdose

Symptoms: headache, hypervitaminosis D and A, vomiting, diarrhea.
There were no reports of an overdose when using the drug in recommended amounts.

Interaction

Do not apply Duovit simultaneously with tetracyclines and antacids, since it is possible to reduce the absorption of tetracycline and minerals. If the therapy requires the joint use of these drugs, the time interval between doses should be at least three hours.
Because of the possible occurrence of hypervitaminosis A, the simultaneous use of Duovit with agents containing retinol is not recommended.
It is necessary to avoid the use of vitamin E for people who use oral anticoagulants, as the probability of bleeding increases.
During the treatment with sulfonamides, it is recommended to avoid excessive amounts of ascorbic acid to prevent the development of crystalluria.
Riboflavin slows down adsorption and reduces the effectiveness of antibacterial drugs. It should be taken more than 3 hours before or after taking an antibiotic.

Terms of sale

Duovit can be bought without a prescription.

Storage conditions

Store in a dry, dark place at a temperature of up to 25 degrees. Keep away from children.
Shelf life - Three years.

special instructions

Perhaps yellowing of urine is harmless and is caused by the presence of riboflavin in the preparation.
People with diabetes need to know that a single dragee contains about 800 mg of sugar.
The blue and red pellets contain 1084 mg sucrose, 330 mg lactose, 238 mg sorbitol, 270 mg glucose, therefore Duovit is not recommended for persons with congenital intolerance to fructose or glucose, with glucose or galactose malabsorption syndrome and isomaltase or sugarase deficiency.
Azo dyes E110 and E124 are able to cause allergic reactions with asthmatic phenomena.
The development of allergies is also possible in persons with hypersensitivity to acetylsalicylic acid.
Do not take Duovit together with other products containing minerals and vitamins.

For children

Section "Instructions for the use of Duovit" tells how to drink vitamins for children over 10 years old. Children who have not reached the age of ten take these vitamins are contraindicated.

During pregnancy (and lactation)

The drug is approved for use during pregnancy or lactation as prescribed by the doctor.

Reviews about Duovit

Reviews about Duovit vitamins are quite numerous, negative evaluations of the effectiveness of the drug are rare. The doctors' testimonies testify to the absence of allergic reactions to the drug.