Grammidin Neo with anaesthetic #18

Grammidin Neo with anaesthetic instruction manual

You can buy Grammidin Neo with anaesthetic here

Composition

In one Grammidin tablet with an anesthetic, Neo contains 3 mg of gramicidin C (used in the form of dihydrochloride), 1 mg of cetylpyridinium chloride (used in the form of monohydrate), 0.2 mg of hydroxybuproacaine hydrochloride.
In addition, the active ingredients are supplemented with auxiliary substances: colloidal silicon dioxide (aerosil 200), talc, magnesium stearate, potassium acesulfame, mint flavor and sorbitol (Neosorb).

Form of issue

The drug is available in tablets intended for resorption. They are white, round, biconcave, on one side there is an inscription "GR". The package usually contains 18 tablets. - 2 blisters on 9 tablets. or 3 blisters according to 6 tables.

pharmachologic effect

For Grammidin, an anesthetic of Neo is characterized by antiseptic, antimicrobial and local anesthetic action.

Pharmacodynamics and pharmacokinetics

The combined preparation includes an antimicrobial component - gramicidin C, antiseptic - cetylpyridinium chloride and local anesthetic - oxybuprocaine, which gives an analgesic effect and the drug as a whole is effective in infectious inflammatory diseases of the oropharynx.
The mechanism of action of gramicidin C is based on its ability to increase the permeability of cytoplasmic membranes of microbial cells, causing a violation of stability and death of microorganisms (most Gram + and Gram-).
As a local anesthetic, oxybuprokain anesthetizes locally on the mucous membrane in the mouth and throat - acts through a reversible blockade of nerve signaling through the axons (long processes) of nerve cells.
Cetylpyridinium chloride is an antiseptic that suppresses reproduction and growth of infectious and inflammatory pathogens in the mouth and throat.
Due to its anesthetic effect, antimicrobial action removes inflammation, softens unpleasant sensations when swallowing, and increased salivation contributes to natural mechanical cleansing of the throat and mouth.

Pharmacokinetics

The drug acts topically, practically does not undergo absorption in the digestive tract and does not give systemic effects.

Indications for use

    angina;
    tonsillitis;
    gingivitis;
    acute pharyngitis;
    stomatitis;
    parodontosis and other infectious-inflammatory processes in the oral cavity or in the throat.

Contraindications

Grammidin with anesthetic Neo should not be taken to patients who have hypersensitivity reactions to any of the pill components, and also:
    children up to 4 years;
    women breastfeeding;
    pregnant women during the first trimester.

Side effects

    temporary loss of language sensitivity;
    allergic reactions.

Instructions for use Gramidine with an anesthetic Neo (Method and dosage)

Daily doses depending on age

    Adults and children over 12: not more than 3-4 tablets per day.
    Children 4-12 years: 1 -2 tablets.
If there is no therapeutic effect after 7 days of therapy, it is recommended to consult a doctor.
Instructions for the use of tablets: slowly dissolve one at a time, do not chew! Take after meals, as approximately 1-2 hours after taking the pill should refrain from food and drinks.

Overdose

Previously it was not registered.

Interaction

In combination with antimicrobial agents of local or systemic action, their effects intensify.

Terms of sale

Sold in pharmacies and on medical portals without a prescription.

Storage conditions

Temperature regime: up to + 25 ° С.

Shelf life

Tablets are suitable for 2 years from the date available on the original packaging.

Analogues

Gramidine for children

Reviews

From the comments and discussions on the forums you can see that most of the reviews are positive. Patients taking pills for various diseases of the oral cavity or throat state that:
    this is a very good preparation of domestic production;
    the best pills for the throat with a pleasant taste and relieving pain;
    the medicine really helps.