Structum 500mg #60

Instruction for Structum

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The drug Structum represents the pharmacological group of medicines drugs that regulate the metabolic processes in the cartilaginous tissue, as well as protect it from negative effects (chondroprotectors). It is used to treat various pathologies of the structures of the musculoskeletal system, accompanied by damage to the cartilaginous tissue.

Composition and form of release

The drug Structum is manufactured in a dosage form gelatin capsules for oral administration (oral administration). They have a casing of blue color, the contents are in the form of a powder of whitish cream coloring, small sizes (size No. 0). The main active ingredient of the drug is chondroitin sulfate in the form of a sodium salt, its content in one capsule is 500 mg. It also includes auxiliary substances, which include:
    Carmine indigo.
    Gelatin.
    Titanium dioxide.
Capsules of Structum are packaged in a blister of 12 pieces. Cardboard pack contains 5 blisters with capsules (60 capsules), as well as instructions for using the drug.

Pharmacodynamics and pharmacokinetics

The main active component of capsules Structum chondroitin regulates metabolic processes (metabolic processes) in tissues of hyaline and fibrous cartilage. It stimulates synthetic processes, in particular the formation of glycosaminoglycans, which are the main structural component of the intercellular substance of the cartilaginous tissue. Due to this, the drug reduces the intensity of the course of degenerative processes, accompanied by damage to the cells and intercellular substance of the cartilaginous tissue. To a lesser extent chondroitin influences the metabolic processes in bone tissue, it promotes its early recovery, and also reduces the intensity of resorption (washing away) of calcium salts, imparting strength to the mineral matrix. Due to such biological effects, this drug has a protective effect on the cartilaginous tissue (chondroprotective effect), and also reduces the severity of the inflammatory reaction.
After taking the capsule of Structum, the active ingredient is taken in quickly enough and absorbed into the systemic bloodstream 70% from the intestinal lumen by 70%. Chondroitin is evenly distributed in tissues, followed by accumulation in cartilage and bone. Partly it is excreted in the urine by the kidneys.

Indications for use

The reception of capsules of Structum is indicated as a means of pathogenetic therapy (treatment aimed at reducing the severity of manifestations of the pathological process by restoring the functional state of cartilage and bone tissue) diseases accompanied by eating disorders and destruction of cartilaginous tissue (degenerative-dystrophic processes) - osteochondrosis, osteoarthritis with localization in any joints.

Contraindications

Absolute medical contraindication to the reception of capsules of Structum is the individual intolerance of any of the components of the drug, which mainly leads to the development of an allergic reaction. Also, the drug is not used in patients under the age of 15, since its safety and effectiveness for children remain unproven.

Dosing and Administration

Capsules of Structum are intended for oral administration. They are taken whole, without chewing and drinking with a sufficient amount of water. The average therapeutic dosage and regimen for adults and adolescents over 15 years is 50 mg (1 capsule) 2 times a day. The duration of the initial course of therapy should be at least six months. The therapeutic effect after the course of therapy is usually maintained for several months (3-5 months). If necessary, after a certain period of time, the course of treatment can be re-appointed, and the doctor sets the duration and mode of application of the medicine individually, depending on the degree of severity, the effectiveness of the previous course of therapy.

Side effects

Against the background of taking the drug capsule Structum, it is possible to develop negative pathological reactions from various organs and systems, these include:
    The digestive system - nausea, accompanied by periodic vomiting.
    Allergic reactions - a rash on the skin, its itching, characteristic changes resembling a nettle burn (hives), the appearance of red spots (erythema).
If adverse side effects occur, the capsules should be discontinued and consult a medical professional who will determine whether to continue the course of therapy.

special instructions

Before taking capsules Structum, it is important to carefully read the instructions to the drug. There are several specific indications that should be taken into consideration during the application of this medication, including:
    With special care under medical supervision, as well as laboratory monitoring of the functional state of the blood coagulation system (hemostasis), the drug is used in individuals with concomitant disorders of thrombus formation.
    The active ingredient of capsules of Structum may increase the therapeutic effects of drugs of the pharmacological group, indirect coagulants, fibrinolytic and antiplatelet agents, therefore, when combined, medical supervision and laboratory monitoring of the functional state of the hemostasis are required.
    Since there is no reliable confirmed data on the safety of this drug on the developing fetus and the infant, its use for pregnant and lactating women is not recommended.
    The active component of this drug does not directly affect the nervous system, therefore, against the background of its use, it is allowed to engage in work, which is associated with the need for sufficient concentration of attention and speed of psychomotor reactions.
In the pharmacy chain, Structum capsules are dispensed without a doctor's prescription. If there is any doubt about the use of this medication, it is recommended that you consult with a medical professional.

Overdose

If there is a significant one-time excess of the recommended therapeutic dose of Structum capsules, nausea, vomiting, and diarrhea may develop. In case the taken dose exceeds 3 g, there may be a pinpoint bleeding in the skin (hemorrhagic rashes). In such cases, washing of the stomach, intestines, intake of intestinal sorbents (activated charcoal), as well as symptomatic therapy in a hospital are performed.

Terms and conditions of storage

The shelf life of capsules of Structum is 3 years. They must be stored in intact original packaging, dark, dry, inaccessible to children at an air temperature of not more than + 25 ° C.