Progestogel 1% 80gr

Progestogel instruction

You can buy Progestogel here

Gel Progestogel refers to hormonal drugs for external use. It contains the hormone progesterone and is used to treat various pathologies of women, mainly associated with the lesion of the mammary glands.

Composition and form of release

The Progestogel gel has no color, it is translucent, slightly opalescent. The main active substance of the drug is progesterone. Its content in a single dose is 25 mg (800 mg of progesterone in a tube). Also, the composition of the gel includes auxiliary como, which include:
    Trolamine.
    Macrogol.
    Octyldodecanol.
    Ethanol.
    Carbomer 980.
    Purified water.
The Progestogel gel is contained in an aluminum tube in the amount of 80 g. The cardboard pack contains one tube, a special applicator-doser and instructions for the use of the drug.

Pharmacodynamics and pharmacokinetics

Active gel substance Progestogel progesterone is a hormone that produces the yellow body of the ovaries after the release of the oocyte (the process of ovulation). It blocks the receptors of cells to estrogen, due to which it reduces its effect on the body. The main therapeutic effect of the drug develops due to the accumulation of progesterone in the tissues of the mammary gland with external use of the drug. Progesterone helps reduce edema of the tissues, squeezing the ducts of the mammary gland, as well as reducing the intensity of the lactopoiesis process (production of breast milk) by blocking the receptors to the hormone prolactin. Since progesterone blocks receptors for estrogen, it reduces the intensity of proliferation (division) of cells of the alveoli and ducts of the mammary gland.
With the external application of the Progestogel gel, the active substance accumulates directly in the tissues of the breast, without being metabolized in the liver. In the systemic circulation, progesterone is absorbed in small concentrations, after which it is converted in the liver to inactive decay products, which are excreted in the urine and partly with feces.

Indications for use

Use of the gel The Progestogel is shown in the pathology of the mammary glands, accompanied by increased proliferation of their tissues - diffuse fibrocystic mastopathy, mastodynia.

Contraindications for use

There are a number of medical contraindications to the use of the Progestogel gel, these include:
    Nodular form of fibrocystic mastopathy.
    Malignant neoplasm (cancer) of the breast and genital organs (if used as a monotherapy).
    Pregnancy in the II-III trimester of the current.
    Tumor neoplasms of unknown origin.
    Individual intolerance to any of the components of the drug.
Before the appointment of the Progestogel gel, the doctor must be sure that there are no contraindications to the use of the drug.

Dosage and route of administration

With the help of a special applicator-doser gel Progestogel is applied to the skin of the breast in the area of ​​the pathological process. Dosing regimen is 1-2 application of the 1st dose of gel during the day. Also, the drug can be used in the second half of the menstrual cycle (usually from 16 to 25 days). The average course of treatment is applying the gel in 2-3 cycles. In general, the duration of treatment and dosage the doctor determines individually.

Side effects

In general, the Progestogel gel is transferred well enough. On the part of the reproductive system, pain can develop in the area of ​​the mammary glands, a sensation of hot "tides" of blood to the skin of the face, a decrease in libido (sexual attraction to the opposite sex), metrorrhagia (uterine bleeding). It is also possible the appearance of allergic reactions on the skin in the form of redness, rash and itching.

special instructions

To avoid the development of complications and to obtain the maximum therapeutic effect during the application of the Progestogel gel, several specific indications must be considered:
    After applying the drug on the skin, rub the gel or massage the breast gland is not recommended.
    For a more accurate dosage, it is important to use an applicator-dispenser.
    After applying the gel Progestogel to the skin of the breast is important to avoid getting direct sunlight on it.
    There are no reliable data on the effect of the drug on the speed of psychomotor reactions and the possibility to concentrate attention to today.
In the pharmacy chain, the Progestogel gel is dispensed only by prescription. It is not recommended to use it independently without the appropriate doctor's prescription.

Overdose

Due to the low absorption of the active substance of the Progestogel gel into the systemic blood stream, the possibility of an overdose is unlikely.

Terms and conditions of storage

The term of the Progestogel gel is 3 years from the date of manufacture. The drug is stored in a dark place inaccessible to children at an air temperature of no higher than 25 ° C.