Cifran tabs 500mg #10

User manual for Cifran

You can buy Cifran on this page

Composition

One tablet contains 250, 500 or 1000 mg of the active component of ciprofloxacin. Additional substances: talc, hydroxypropylmethylcellulose, sodium alginate, magnesium stearate, crospovidone, colloidal silica gel on anhydrous basis, sodium hydrogen carbonate.
Cifran ST additionally contains 600 mg of tinidazole.
100 ml of the solution contains 200 mg of ciprofloxacin lactate.

Form of issue

The medication is released in tablet form and in the form of a solution.

pharmachologic effect

Cifran, is it an antibiotic or not?

Yes, the principle of antimicrobial action is based on the obstacle to the multiplication of bacteria, which leads to the death of the microorganism. The drug acts on gram-positive bacteria and gram-negative flora, resistant to the action of aminoglycosides, penicillins and cephalosporins. The antimicrobial effect is observed in all organs and systems, suppressing the infectious process and inflammation, which makes it possible to use an antibiotic for toothache.
The active ingredient in the preparation of Ciprolet is ciprofloxacin, therefore, in fact, Ciprolet and Cyphran are the same in pharmacological action.
Cifran OD - prolonged ciprofloxacin long-acting.

Pharmacodynamics and pharmacokinetics

With respect to the gram-negative flora, a bactericidal (destroying) effect is manifested in the phase of division and dormancy (the active substance acts on the enzyme DNA-girase and causes death, lysis). On gram-positive flora, Cyflan 500 acts only during division. In macroorganisms there is no enzymatic DNA-gyrase, which makes ciprofloxacin low-toxic to humans. The parallel development of resistance to other antimicrobial medicines (tetracyclines, aminoglycosides) against the background of treatment is not observed. Stability is formed very slowly.

Indications for the use of Cifran

From what tablets Cifran? Medication is prescribed for bacterial infections caused by microorganisms that are sensitive to the effects of the antibiotic ciprofloxacin.

Diseases of the respiratory system:

    cystic fibrosis;
    pneumonia;
    bronchitis (acute and chronic form);
    bronchiectatic disease.

Diseases of ENT organs:

    tonsillitis;
    otitis;
    sinusitis;
    frontitis;
    pharyngitis.

Diseases of the genito-urinary tract:

    adnexitis;
    cystitis;
    pyelonephritis;
    endometritis;
    salpingitis;
    gonorrhea;
    chlamydia;
    oophoritis;
    a tubular abscess;
    chancroid.

Abdominal infections:

    cholera;
    typhoid fever;
    shigellosis;
    peritonitis;
    salmonellosis.
From what else can be appointed Cifran: burns, phlegmon, septic arthritis, osteomyelitis, infected ulcers, sepsis.
Cifran ST is prescribed for severe mixed infections: empyema, sinusitis, pressure sores, dysentery.

Contraindications

    intolerance to the active component of ciprofloxacin;
    bearing pregnancy;
    lactation.
With mental illness, pronounced atherosclerotic changes in the brain, epileptic syndrome, renal system pathology, the drug is administered with caution, weighing possible complications and the expected result. It is not recommended for elderly people.

Side effects (adverse reactions)

The cardiovascular system:

    drop in blood pressure;
    cardiopalmus;
    arrhythmias.

The digestive tract:

    Cholestatic jaundice (more often in predisposed individuals);
    a violation of appetite;
    diarrheal syndrome;
    nausea;
    epigastric pain;
    hepatitis hepatitis.

Nervous system:

    anxiety;
    headache;
    fast fatiguability;
    sleep disorders;
    peripheral paralgesia (impaired perception of pain syndrome);
    hyperhidrosis;
    various psychotic reactions.

Sense organs:

    impaired auditory perception;
    noise in ears;
    violation of color perception, diplopia;
    perversion of taste.

Genitourinary tract:

    crystalluria;
    hematuria;
    dysuria;
    glomerulonephritis;
    interstitial nephritis.
Possible allergic response in the form of urticaria, drug fever, epidermal necrolysis. Rarely recorded myalgia, arthralgia, tendon ruptures, a change in the blood.

Instructions for use Cifran (Method and dosage)

How to take the drug: to increase the bioavailability is strongly recommended to take the pill on an empty stomach. During the entire treatment period, increased water intake is required. Infusion solution administration is possible only intravenously for 0.5-1 hour.
Treatment of uncomplicated pathology of the genito-urinary tract: every 12 hours, 250 mg.
Treatment of prostatitis, severe pathology of the urinary system: twice a day for 500 mg.
Treatment of ENT pathology, respiratory system diseases, typhoid fever: 500 mg every 12 hours. In severe cases, the drug should be administered parenterally according to the scheme: 200 mg (100 ml bottle) slowly intravenously twice a day (a single dose up to 400 mg is possible).
Instruction on Cifran ST: tablets must be taken after meals, without destroying the integrity of the protective shell. The recommended dosage is -250 \ 300 mg (the ratio of active substances ciprofloxacin and tinidazole) twice a day for 2 tablets.
Instructions for use Cyphran OD: taking medication on an empty stomach accelerates the antibacterial effect. Recommended treatment regimen: 250 mg 2-3 times a day.
Overdose
High doses of the drug increase the severity of adverse reactions. Recommended induction of vomiting, adequate hydration, the conduct of asymptomatic therapy. A special antidote has not been developed.

Interaction

The level of theophylline increases with simultaneous treatment with ciprofloxacin. It is recommended to maintain a 4-hour window between Citrane and preparations containing zinc, iron, magnesium, sucralfate, aluminum. Anti-inflammatory, non-steroidal drugs enhance the stimulating effect of the drug on the nervous system. Required control coagulogram when taking Warfarin.

Storage conditions

In a dry place, the temperature regime is up to 25 degrees.

Shelf life

2 years. When the precipitate falls in the solution, the medication is considered unfit.

special instructions

To prevent crystalluria, sufficient fluid intake during the treatment period is required. It is recommended to avoid sun exposure.

Compatibility with alcohol

The slowing down of the speed of psychomotor reactions is recorded. Alcohol increases the hepatotoxic effect of the drug.

Reviews of Cifran

Medical portals and forums contain only positive reviews about the drug.
Reviews for Cifran OD characterize the drug as a highly effective antibiotic of a broad spectrum with good tolerability.
Reviews on Cifran ST testify to the effectiveness of the medication in the therapy of dysentery and diarrhea syndrome.