Ciprolet tabs 500mg #10

Ciprolet user manual

You can buy Ciprolet here

See also - Ciprolet A

Composition

The composition contains the active substance ciprofloxacin, as well as additional substances: water injection, edetate disodium, hydrochloric acid, benzalkonium chloride as a solution, as well as sodium chloride.

Form of issue

The drug is available in the form of eye drops, a solution for infusions and tablets.
Eye drops Ciprolet 3 mg / ml are available in the form of a vial.
Solution for injections of 2 mg / ml.
Tablets of 10 pieces in a blister, 250 mg and 500 mg.

pharmachologic effect

Ciprolet is an antibiotic or not? Yes, Ciprolet is an antibiotic. The main component is ciprofloxacin. The active component is a derivative of fluoroquinolone. The mechanism of action is aimed at suppressing the DNA-gyrase of a bacterial cell, which leads to a disruption in the synthesis of DNA, slowing down the growth and multiplication of microbes. As a result of pronounced morphological changes, the microbial cell dies under the influence of the antibacterial Ciprolet. The bactericidal effect is manifested in the period of division and dormancy of gram-negative microorganisms. With respect to gram-positive flora, a bactericidal effect occurs only during division. Cells of a macroorganism do not contain DNA-gyrase, which completely excludes toxic effects on the human body. The drug does not cause resistance to other antibacterial drugs. Ciprolet is active against aerobic flora, enterobacteria, gram-negative flora, chlamydia, listeria, mycobacterium tuberculosis, yersinia, campylobacteria, proteas, mycoplasmas, etc. The drug does not have a bactericidal and bacteriostatic effect on treponem pallidum (an agent of syphilis).

Pharmacodynamics and pharmacokinetics

Quickly absorbed from the gastrointestinal tract. Well penetrates into bone tissue, saliva, skin, muscle corset, lymph, and also bile, lungs, kidneys, liver, tonsils, peritoneum, pleura, ovaries, seminal fluid.
An antibiotic is excreted through the kidneys. About 50-70 percent out of the bladder, and about 20 percent with feces.

Indications for the use of Ciprolet

Ciprolet tablets - what are they from? The drug is prescribed for bacterial lesions of the respiratory system (cystic fibrosis, bronchitis, bronchiectatic disease, pneumonia, tonsillitis), ENT organs (tonsillitis, pharyngitis, otitis media, mastoiditis, sinusitis, sinusitis), genitourinary system (salpingitis, cystitis, pyelonephritis, oophoritis, tubular abscess, adnexitis, prostatitis, gonorrhea, chlamydia, chancroid, pelivioperitonitis, pyelitis), digestive system (peritonitis, typhoid fever, salmonellosis, intraperitoneal abscesses, yersiniosis, campylobacteriosis, cholera, shigellosis), skin , abscess, burns, infected ulcers, wounds), osteoarticular system (sepsis, septic arthritis, osteomyelitis).
What helps Ciprolet yet? The medicinal preparation is prescribed for the prophylaxis of infectious lesions after surgical operations.
Eye drops Ciprolet indications for use have the following: conjunctivitis, blepharitis, barley.

Contraindications

Contraindications to the drug are as follows. Ciprolet is not prescribed in pediatric practice until adulthood (formation of the bone system, skeleton), with intolerance to ciprofloxacin, pregnancy, during lactation. When cerebral circulation is disturbed, atherosclerosis of cerebral vessels, with epileptic syndrome, epilepsy, mental disorders, pronounced pathology of the liver, kidneys, elderly people are appointed after consultation of specialists.

Side effects

The digestive tract: vomiting, diarrhea syndrome, flatulence, epigastric pain, nausea, bloating, cholestatic jaundice, decreased appetite, hepatonecrosis, hepatitis.
Nervous system: insomnia, dizziness, anxiety, fatigue, peripheral paralysis, "nightmarish" dreams, limb tremor, increased intracranial pressure, increased sweating, hallucinations, depression, confusion, various psychotic reactions, cerebral thrombosis, syncope, migraine.
Organs of the senses: a decrease in hearing, tinnitus, a violation of taste perception, diplopia. Possible development of tachycardia, a drop in blood pressure, heart rhythm disturbances, the development of anemia, granulocytopenia, leukocytosis.
Genitourinary system: polyuria, dysuria, glomerulonephritis, crystalluria, hematuria, interstitial nephritis, disturbance of the nitrogen-producing function of the kidneys.
Ciprolet can provoke an allergic response, hives, arthralgia, tendovaginitis, arthritis and other side effects.

Instructions for the use of Ciprolet (Method and dosage)

Consider how to take the drug.

Ciprolet tablets, instructions for use

The medicine is taken orally 2-3 times a day for 250 mg; in severe disease, the dosage is increased to 0.5-0.75 grams.
Infections of the genitourinary system: twice a day for 0.25-0.5 grams for 7-10 days.
Uncomplicated gonorrhea: once 0.25-0.5 grams.
Gonococcal infection in conjunction with mycoplasmosis, chlamydia: every 12 hours at 0.75 grams, the course - 7-10 days.
Chancroid: twice daily Ciprolet 500 mg.
The drug in the tablets is swallowed completely, washed down with liquid.

Eye drops Ciprolet, instructions for use

Drip for 1-2 drops of funds every 4 hours. If a serious defeat - drip 2 drops every hour. As you recover, you can limit the intake of antibiotic for dosage and frequency.
Some doctors believe that you can use a drop like an ear. However, it should be borne in mind that this is not their direct purpose. It must be remembered that these are drops for the eyes.

Instructions for injecting a solution

Intravenous administration is carried out drip for a half hour of 0.2 grams.
Osteomyelitis therapy takes about 2 months.
Chronic carriage of salmonella: twice a day for 0.2 grams, course 4 weeks.
After intravenous infusion, they switch to taking a tablet form.

Overdose

It is manifested by increased severity of side effects. Specific antidote is not developed. It is necessary to wash the stomach, carry out peritoneal dialysis, hemodialysis.

Interaction

Ciprolet prolongs the half-life, increases the concentration of indirect anticoagulants, oral hypoglycemic drugs due to a decrease in the activity of microsomal oxidation in hepatic cells of hepatocytes. Ciprofloxacin lowers the prothrombin index. Combination with other antibacterial agents leads to synergism. Ciprolet is effectively used in conjunction with azlocillin, ceftazidime, beta-lactams, isoxazole penicillins, vancomycin, clindamycin, metronidazole. The drug increases the nephrotoxicity of cyclosporine, raises the level of serum creatinine. Preparations of the NSAID group, in addition to acetylsalicylic acid, can cause convulsive syndrome. The infusion solution is incompatible with infusion solutions according to pharmaceutical indices. It is inadmissible to mix solutions for intravenous infusions with solutions whose pH exceeds the value of 7.

Storage conditions

Do not allow children to the drug.
In a dry, dark place, the temperature should not be above 25 degrees Celsius. In no case can not be frozen.
Shelf life - 2 years.

special instructions

It requires control of blood pressure, heart rate, ECG with the simultaneous administration of general anesthetics (barbituric acid derivatives) and ciprofloxacin. Excess daily dosage can lead to crystalluria. Ciprolet influences the management of transport, the concentration of attention. Patients with organic lesions of the brain, vascular pathology, epilepsy, convulsive seizures in the history of the drug Ciprolet is prescribed in exceptional cases, according to "vital" indications. Before carrying out antibacterial therapy, it is necessary to exclude pseudomembranous colitis. Treatment is stopped at the first signs of tendovaginitis, the appearance of pain in the tendons. It is important during treatment to avoid insolation.
In Wikipedia, there is no article on the preparation, the online encyclopedia contains only information on the active substance ciprofloxacin.

Analogs of Ciprolet

Analogues of Ciprolet in composition are drugs: Ciprofloxacin, Cifran and others.

Ciprolet and Cifran the same thing?

Cifran is an analogue of the drug for the active substance.

For children

It is not recommended to use drugs for children under 18 years. Eye drops for children also do not apply.

Ciprolet and alcohol

Compatibility with alcohol is absent. In the best case, the interaction with alcohol increases the side effects of the drug. However, the consequences may be more deplorable: severe poisoning and death.

In pregnancy

Contraindicated in pregnancy and breastfeeding.

Reviews about Ciprolet

Reviews of Ciprolet tablets
In general, the drug, of course, helps, because it is an antibiotic. However, it is worth remembering that it is for this reason that it should be taken only in extreme cases, so as not to harm the health, especially at doses exceeding 500 mg. In particular, the annotation says that you can not take Ciprolet before adulthood, as this can adversely affect the skeleton. Also on the Internet there are reviews of the side effects of this drug, such as weakness, dizziness, heaviness of breathing.
The drug is successfully taken with cystitis, but it is not recommended to stay in the sun for a long time while taking this antibiotic.
Eye drops Ciprolet reviews have the following
Effective with conjunctivitis, blepharitis, barley. Drops are inexpensive.