Cifran OD tabs 1000mg #10

Cifran OD user manual

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See also - Cifran

Cifran Od - a drug aimed at the destruction of infections and inflammatory processes in any tissues and organs of man, thanks to the active substance, which is an antibiotic. The drug is released as a tablet, and in the form of solutions for injections, ointments and drops in order to be able to work on any desired point of the body.

Indications for use and composition

Cifran od is one of the strongest among all antibiotics, therefore it is indicated in the treatment of inflammatory infections:
    Pyelonephritis and cystitis
    IVH, chronic bronchitis, pneumonia
    Gonorrhea and skin diseases
    Peritonitis and other abdominal infections
    Infectious diseases, joints and bones
    Infectious diarrhea
    Even anthrax and typhoid fever.
In addition to the main active ingredient, i.e. ciproflaxocin, talc, colloidal dioxide, magnesium stearate, hypromellose, crospovidone, sodium alginate and bicarbonate are present as adjuvants in the drug. They enhance the effect of exposure. For example, crospovidone releases active ingredients faster, magnesium stearate is administered as a filler, hypromellose eliminates discomfort in the eyes, and colloidal dioxide directs the work of the digestive tract.
In the film-forming agent: white opadrai, hypromellose, talc, purified water. Its functions: protection from moisture; smooth, shiny shell facilitates easy slipping of the tablet into the esophagus; due to the lack of soy lecithin reduced allergic reactions.

Healing properties

Cifran od acts directly on the DNA of the bacterium, regardless of whether it is at rest, or multiplies and develops. The drug suppresses the DNA-gyrase, because of which the bacteria do not combine two strands of DNA. Synthesis of proteins becomes impossible.
Ciprofloxacin equally easily penetrates into liquid media and tissues: saliva, mucous membranes, sperm, lymph, prostate, lung, adipose tissue, muscles, bones and so on. This explains the wide range of drug use.
Of the body, half of the drug is excreted through the kidneys, another 15% - also with urine, but already in the form of metabolites (metabolic products), the rest is removed by the intestine. Half-life is about 7 hours.

Tablets Cifran OD

In the blister are 10 tablets. The content of ciprofloxacin in one tablet is either 500 mg or 1000 mg. Dosage and duration of treatment depend on the severity of the infection, the susceptibility to the drug of bacteria, and the state of the kidneys of patients.
For ease of taking the tablets have an oval shape. The contents of the tablet are bitter in taste, but thanks to the shell during the ingestion of the drug, bitterness is not felt. On the break, the tablet has a white color.

Dosing and Administration

Take the pill, squeezed them with plenty of water, after eating. For different diseases and severity the dosage is not the same (it is prescribed by a doctor). Usually treatment lasts one two weeks, but in especially neglected cases, the doctor can extend the medication up to 1 month.
Orally ingested digitum od is taken twice a day at a dosage of 250-750 mg. In any case, intake even for an adult should not exceed 1500 mg.

Eye drops Cifran OD

Eye drops Cifran od are designed to treat inflammation of the eye of an infectious nature. They can also be used as ear drops to treat otitis. Drops are available in 10 ml each in a vial that is convenient for instillation without a pipette. 1 ml of drops for eyes. Cifran is contained in the form of ciprofloxacin hydrochloride with a mass of 3 mg. Drops are also used for conjunctivitis, blepharitis, keratitis, barley (meybumitis), otitis and as a prophylaxis against infections in the postoperative period on the eyes and ears.

Dosing and Administration

In case of severe infection, drop by drop 2 hours, at moderate - 1 drop every 4 hours. Dosage is reduced when the condition improves. When treating the eye with ointment, a squeezed shaft about 1 cm long is inserted into the diseased eye for the lower eyelid.

Solution for infusions Cifran Od

Cifran in the form of a solution for infusion is poured into 100 ml vials. In 1 ml of the solution contains ciprofloxacin 2 mg; thus, the vial contains 200 mg of active substance. For injections, the preparation is also packed into ampoules, indicating the amount of active substance on the box and ampoule. The frequency of injections and the dose of a medicine depends on the type and neglect of the disease, as well as on the size of the lesion.

Dosing and Administration

Intravenous also can be administered twice a day for 200-400 mg. Although this can be done and jettisoned, but for greater efficiency it is desirable that the duration of the dropper is about half an hour.

Contraindications and precautions

In some cases, treatment with this drug is categorically contraindicated:
    Before the age of eighteen
    During pregnancy and breastfeeding
    Patients with epilepsy
    With organic damage to the brain
    People who are prone to seizures
    With pseudomembranous colitis, because it is already caused by excess antibiotics
    With deficiency of glucose-6-phosphate dehydrogenase
In addition, the drug can not be taken simultaneously with theophylline and tizanidine, as well as with increased sensitivity of the body to fluoroquinols.
It is possible to use, but with caution, patients with cerebral atherosclerosis and with renal insufficiency. A large amount of water for swallowing the tablet is caused by the possibility of crystalluria (the formation of crystals in the urine).

In pregnancy and lactation

Since this antibiotic penetrates almost all tissues and liquid media of the body, it will also get into the fetus. Therefore, during pregnancy, take this remedy should not be. During lactation it is necessary to specifically assess the threat to the health of the mother. If the use of this drug is necessary, then you need to give up breastfeeding.
Local application (treatment of conjunctivitis) is possible during pregnancy, and during breastfeeding.

Cifran OD Interactions

Simultaneous administration of the drug with tinazidine can lead to hypotensive and sedative effects: simultaneously with a drop in pressure, the central nervous system is suppressed. This is akin to the effect on the body of clonidine.
With simultaneous acceptance with theophylline, the drug dramatically increases the level of theophylline in the blood, which is fraught with unpredictable adverse reactions.
Antacids slow the absorption of ciprofloxacin and its excretion, so the drug should be administered either within 2 hours, or 6 hours after antacids. When taken with omeprazole, the absorption time of ciprofloxacin is reduced by 20%.
When interacting with anticoagulants, the effect of the latter increases. It is necessary to have constant control over patients taking kidney medications, as ciprofloxacin is slowed, and an increased concentration in the kidney and blood plasma is possible.
When interacting with non-steroidal anti-inflammatory drugs (excluding aspirin), seizures may occur.

Overdose and side effects

If you follow the instructions recommended by your doctor, there are usually no side effects. But they are always possible with overdoses. And because of the total penetration of the drug into all tissues, malfunctions in any body systems are possible.
Gastrointestinal tract: nausea and vomiting, abdominal pain, flatulence and diarrhea. People with a diseased liver can experience cholestatic jaundice, hepatitis, hepatonecrosis.
Cardiovascular and hematopoietic system: heart rhythm disturbances, tachycardia, blood rush to the head and face, lowering of arterial pressure, as well as anemia, reduction of leukocytes in the blood and a decrease in blood clotting and coagulation.
Genitourinary system: crystalluria (especially in alkaline urine and low diuresis), urinary retention, urethral bleeding, albuminuria, acute renal failure.
Sensory organs: change in color perception and photophobia, noise in the ears and hearing loss, changes in taste and perception of odors.
Nervous system: dizziness, irritability and insomnia, headache, fatigue, constant anxiety and nightmares, confusion and hallucinations, depression, migraine and fainting.
To learn more about the treatment of noise in the ears, see: Tinnitus: We are looking for the causes and the way of treatment.

Application features

Many patients who use digiton od, there is a reaction photosensitivity. Therefore, they should not be exposed to direct sunlight and ultraviolet lamps. Otherwise, itching, rash and redness of the skin may occur. If there is pain in the bones and tendons, then treatment should be completed - a rupture of tendons and ligaments is possible.
This is one of the few antibiotics that can be taken on a doctor's recommendation once a day. In addition to all, even mutating microbes can not ignore the drug and perish.

Terms and conditions of storage

Since it is not recommended to take the drug before the age of eighteen, it must be stored in places inaccessible to children. To avoid disruption of the integrity of the tablets, they should be stored in a dry place. The temperature during storage should not exceed 25 ° C. The shelf life of the drug under these conditions is 2 years.
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