Fromilid Uno tabs 500mg #14

Fromilid Uno user manual

Reed more and buy Fromilid Uno on this page

See also - Fromilid

The drug Fromilid Uno refers to antibiotics from the macrolide group.

Form of formulation and composition of the preparation

The preparation of Fromilid Uno is available in the form of tablets for oral administration. The tablets are yellow, oval, convex on both sides, covered with a protective film shell, long-lasting. The drug is packaged in blisters of 5 or 7 pieces (1-2) in a cardboard box with the attached annotation with a full description of the characteristics of the antibiotic.
Each tablet contains 500 mg of the active ingredient Clarithromycin, as well as a number of auxiliary components.

Indications for use

Tablets Fromilid Uno is prescribed to patients inside for the treatment of inflammatory-infectious diseases caused by Clarithromycin-susceptible pathogens. Indications for the use of the drug are:
    acute and chronic inflammatory diseases of the upper respiratory tract and oropharynx - tonsillitis, pharyngitis, tonsillitis, otitis media, sinusitis, sinusitis, laryngitis, tracheitis, laryngotracheitis;
    Inflammatory-infectious diseases of the lower respiratory tract - bronchitis, pneumonia, including community acquired, lung abscess;
    Inflammatory and infectious diseases of the skin and soft tissues - furuncles, carbuncles, erysipelas, streptoderma, staphyloderma, folliculitis.

Contraindications

Before starting therapy, the patient must be sure to take blood tests and swabs from the throat and nose to differentiate the pathogen. Before taking the tablets, you should carefully read the product's annotation, since Formylid Fromilid Uno has a number of contraindications:
    individual intolerance to the components of the drug;
    the patient's age is up to 12 years (this is due to the fact that the experience of using the drug in pediatric practice is absent, and the safety of the antibiotic is not established);
    pregnancy in 1 trimester;
    the period of breastfeeding;
    congenital lactose intolerance, lactase insufficiency;
    severe diseases of the kidneys and liver, accompanied by a violation of the function of the body;
    chronic renal failure.
Relative contraindications to the use of the drug are:
    pregnancy 2 and 3 trimesters;
    myasthenia gravis;
    diabetes;
    simultaneous therapy with drugs, the metabolism of which occurs in the liver.

Dosing and Administration

The dose of the drug is selected individually for each patient, depending on the diagnosis, the severity of the disease and the characteristics of the body. According to the instructions, adolescents older than 12 years and adults are prescribed 500 mg of the drug once a day. In the presence of complications or severe infectious disease, the daily dose of the drug the doctor can increase to 1 g (2 tablets) at one time.
The duration of the course of therapy, as a rule, is 5-7 days, but in severe cases it can be prolonged up to 14 days.
Patients with severe kidney and liver diseases, accompanied by impaired function of the organs, require an individual dose adjustment, and the treatment is under the supervision of the doctor.

Use during pregnancy and breastfeeding

In the first trimester of pregnancy, the use of the drug Fromilid Uno is contraindicated, since the use of antibiotics from the macrolide group at early stages may provoke fetal development of congenital anomalies and deformities.
In the second and third trimesters of pregnancy, taking the drug is possible only if there are life indications, in the event that the expected benefit for the mother significantly exceeds the potential risk to the fetus.
During breastfeeding, taking Fromilid Uno tablets is contraindicated, since Clarithromycin can be excreted in breast milk. If it is necessary to treat a lactating mother, the question of stopping lactation should be resolved.

Adverse Events

During the administration of the drug, Fromilid Uno, in persons with increased individual sensitivity to Clarithromycin, side effects may develop:
    from the side of the digestive tract - dry mouth, stomatitis, ulceration in the tongue, increased thirst, lack of appetite, heaviness in the stomach, heartburn, belching, nausea, sometimes vomiting, inflammation of the pancreas, increased activity of hepatic transmissions, hepatitis, bloating, diarrhea , development of pseudomembranous colitis;
    from the nervous system - headaches, drowsiness, lethargy, apathy, sometimes dizziness, impaired consciousness, hallucinations (with a significant excess of the dose), a feeling of crawling, shivering of limbs, depression;
    from the skin and mucous membranes - increased sweating, acne, erysipelas, erythema;
    from the side of the heart and blood vessels - violation of the heart rhythm, atrial fibrillation, ventricular flutter, pirouette tachycardia;
    from the hematopoiesis - thrombocytopenia, leukopenia, agranulocytosis;
    from the senses - a temporary decrease in hearing, ringing and noise in the ears, double vision, reduced visual acuity, a violation of taste sensations at the receptor level;
    from the musculoskeletal system - muscular pain, joint pain, myopathy;
    from the organs of the urinary system - interstitial nephritis, the development of acute renal failure;
    allergic reactions - rash on the skin, angioedema, hives, skin hyperemia, Lyell's syndrome, toxic epidermal necrolysis, anaphylactic shock;
    laboratory indicators - an increase in the concentration of creatinine in the blood, increased urea levels, hypoglycemia, lengthening prothrombin time.
When developing one or more of these side effects, the patient should consult a doctor for advice.

Overdose

It is not advisable to intentionally increase the dose prescribed by the doctor, as this may lead to an overdose of Clarithromycin. Clinical signs of macrolide overdose are expressed in the intensification of the side effects described above and the development of acute renal and hepatic insufficiency.
When accidentally ingesting a large number of Fromilid Uno tablets, the patient is washed with a stomach, given at least 6-8 tablets of Activated Carbon and left under observation. If necessary, symptomatic therapy is performed.

Interaction of the drug with other drugs

The preparation Fromilid Uno with caution should be prescribed with hypoglycemic drugs and insulin, since under the influence of Clarithromycin the effect of hypoglycemic agents may be intensified. If this drug interaction is required, correction of the dose of hypoglycemic agents under the supervision of a doctor is required.
Clarithromycin increases the action of cardiac glycosides, analgesics, antibacterial agents. This leads to an increase in the concentration of active agents of these drugs in the blood, respectively, increases the risk of side effects.
The simultaneous administration of the preparation of Fromilid Uno with Simvastatin is contraindicated, as the concentration of Clarithromycin and statins in the blood serum increases, and this increases the risk of myopathy and rhabdomyolysis.
With the simultaneous administration of the drug, Fromilid Uno with carbamazepine or Phenobarbital, the therapeutic effect of Clarithromycin decreases, which should be taken into account not to assign these medications to the patient in parallel.

special instructions

The composition of the tablets of Fromilid Uno includes lactose, therefore the drug is not suitable for patients with congenital intolerance to this component or glucose malabsorption syndrome.
Persons with diabetes should be treated with caution in the treatment with the drug Fromilid Uno. This is due to the fact that Clarithromycin is able to enhance the therapeutic effect of hypoglycemic agents, which increases the risk of a sharp drop in blood sugar.
The experience of using the drug among children under the age of 12 is absent or limited, therefore, Fromilid Uno tablets are not prescribed in pediatrics.
Patients with kidney and liver diseases, accompanied by a violation of their function, including a history, before starting therapy with the drug should always consult a doctor. During the period of treatment, such patients should be constantly monitored by specialists and, if any worsening of the condition occurs, immediately stop taking the drug.
During treatment with the drug, Fromilid Uno, it is necessary to limit driving or the management of equipment requiring precise action. This is due to possible sudden dizziness, double vision and drowsiness in the patient during the taking of tablets.

Leave and storage conditions

You can buy Fromilid Uno tablets without a prescription. Store the package with the drug in a place inaccessible to children at room temperature. Shelf life of the antibiotic is 3 years from the date of manufacture, at the end of this period the tablets should be discarded.