Aktiferrin drops 30ml

Aktiferrin instruction

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Composition

The composition of drops Aktiferrin (100 ml) includes 4.72 grams of ferrous sulphate heptahydrate; 3.56 grams of serine + additional ingredients (potassium sorbate, ethanol, raspberry and cream flavors, water, ascorbic acid, invert sugar syrup).

Form of issue

Drop Aktiferrin released as a transparent yellow-green solution, which has a crimson smell and taste, in bottles of 30 ml.

pharmachologic effect

The drug makes up for iron deficiency.

Pharmacodynamics and pharmacokinetics

For the normal functioning of the body, iron is very important. The substance is a part of hemoglobin, cytochromes and myoglobin, participates in the process of oxygen transfer to all organs and tissues, the stimulator of erythropoiesis. About 60% of the substance is part of the red blood cells (hemoglobin), 1 gram - reticuloendothelial system of the liver and spleen. Iron is contained in the bone marrow, every day there is about 25 mg of the substance.
Alpha-amino acid serine improves the absorption of iron, and a much smaller dose of iron is required. It spreads faster through the body and is absorbed.
Folic acid is involved in the synthesis of amino acids, nucleic acids and nucleotides, and also takes part in erythropoiesis. Acid is very useful for pregnant women, protects against various teratogenic factors.
Absorption of active components occurs in the duodenum and the upper part of the small intestine. Here, about 15% of iron is absorbed. However, if the patient has very low hemoglobin, and erythropoiesis is elevated, then this figure can reach 50%. After 3 hours, the drug reaches its maximum concentration in plasma.
Already in the bloodstream, iron binds to the enzyme transferrin and is transferred to the necessary tissues and organs. The maximum amount of iron reacted with the enzyme is 12 mg.
The process of depotation is carried out in the liver, bone marrow and spleen. Iron can penetrate the placenta and enter the breast milk.
Every day the body loses up to 1 mg of iron, especially it occurs in women during menstruation. After the breakdown of hemoglobin, the iron released in the process can be reused for the synthesis of a new oxygen carrier.

Indications for use

The agent is prescribed to eliminate iron deficiency in the body, with a deficiency of folic acid or serine.
Also, the drug is often used in pregnancy, and in other conditions, when the need for iron is increased.

Contraindications

The medicine is not prescribed:
    with allergies to the components of the drug;
    with hemochromatosis and hemosiderosis;
    with anemia (including lead, sidero-sacral, thalassemia, hemolytic and vitamin B12 deficiency);
    if you take other products containing iron;
    with serious diseases of the digestive tract (stenosis, intestinal obstruction);
    with intolerance to fructose or galactose;
    if regular blood transfusion is performed.

Side effects

Possible occurrence:
    constipation, flatulence, diarrhea, abdominal pain, nausea, bitter taste in the mouth, loss of appetite;
    weakness, headaches, dizziness, rarely - encephalopathy;
    pain or pressure in the chest, sore throat, or toothache;
    allergies, rashes on the skin, anaphylactic shock.
If there were abnormalities in the work of the digestive tract, it is worth trying to reduce the daily dose, the symptoms should disappear.

Instructions for Aktiferrin (Method and Dosage)

The treatment regimen should be determined by the attending physician based on the results of the analyzes and monthly monitoring.
Take a drug less than two months is not meaningful, every 4 weeks should be monitored indicators.

Drops Aktiferrin, instructions for use

Dosage is calculated by the formula 5 drops of medication per kg of patient weight, the agent is taken 3 times a day:
    for infants, the daily dose is 30-45 drops per day;
    for preschool children - 75 - 100 drops;
    for schoolchildren - 150 drops.
To open the medicine bottle, you should press it slightly and turn in the direction of the arrow, after application - tightly close.

Overdose

The highest probability of an overdose in children. Even with the reception of one gram there may be a threat to the life of the child, so the drug should be well hidden.
Symptoms of overdose are: nausea, diarrhea, vomiting, drowsiness, shock and collapse of blood vessels. 5 hours after the onset of the first symptoms, there may be an improvement in the condition, but within 12-48 hours the clinical picture may deteriorate significantly (shock, toxic liver failure, coagulopathy, Chain-Stokes respiration).
Because of toxic hepatitis, jaundice may appear, there may be disturbances from the nervous system, up to the coma. If therapy was performed on time, the likelihood of a fatal outcome is significantly reduced.
First, you should wash the stomach with bicarbonate or phosphate p-am, then take milk and a raw egg.
Deferoxamine (1-2 grams) can be administered by intravenous drip. And one more injection the next day.
Clinically proven ineffectiveness of hemodialysis, it is possible to use peritoneal dialysis.
In very severe conditions, sodium dimercaptopropanesulfonate can be administered.

Interaction

Tetracycline, ciprofloxacin, norfloxacin, ofloxacin, levofloxacin, penicillamine, carbidopa, levodopa and methyldopa can be poorly absorbed by the body under the action of the drug, dosage correction is required.
When combined with thyroxine and zinc, iron salts will be less absorbed in the stomach.
Lemon and ascorbic acid enhance the degree of assimilation of iron.
Calcium, magnesium, chloramphenicol, cholestyramine, antacids containing aluminum, magnesium, calcium or bismuth reduce the resorption of iron.
When combined with glucocorticosteroids, the process of erythropoiesis may increase.
Vitamin E reduces the activity of iron in the body, especially in children.

Storage conditions

Do not let children get into hands. Store at a temperature not exceeding 25 degrees.
Shelf life for syrup, drops - 2 years.

special instructions

When taking medication, you should be careful of patients with bronchial asthma, rheumatoid arthritis, hepatitis, alcoholism, with liver and kidney disease, diabetes mellitus.
Do not take tablets or capsules with black tea, milk, or coffee. Also, do not take in parallel (a period of two hours) raw cereals, solid foods, bread, eggs and various dairy products.
It is possible to stain the feces black. In order to avoid staining black teeth, you should brush your teeth after taking medication, do not drink syrup or drops in undiluted form.

In pregnancy and lactation

Often medicine is prescribed for pregnant women. In any case, the question of the use of the drug should be agreed with the doctor. The drug penetrates into breast milk.

Reviews about Aktiferrin

The drug as a whole has good reviews. It is transferred well, side effects are infrequent. Many people like the relatively low cost and variety of dosage forms. Aktiferrin Compositum was much more approached, as it was better assimilated.

Reviews about Aktiferrin for babies

The drug well raises the level of hemoglobin, the child becomes more active, the skin color improves. However, the side effects still arise, badly washed from clothes.