Sorbifer Durules tabs #50

Sorbifer Durules instruction

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Composition

In one tablet, Sorbifer Durules contains active ingredients: ferrous sulphate 0.32 g, ascorbic acid 0.06 g + excipients (povidone, carbomer 934P, macro 6000, magnesium stearate, polyethylene powder, titanium dioxide, paraffin, hypromellose, yellow iron oxide).

Form of issue

The drug is released in the form of tablets of yellow color, convex, with the letter Z on one side. If the tablet is broken in half, the core of the gray color will be visible. In packages of 30 or 50 pieces.

pharmachologic effect

The preparation of iron has an anti-anemic effect on the body.
INN medicines: iron sulfate + ascorbic acid.

Pharmacodynamics and pharmacokinetics

The therapeutic properties of the drug are due to the presence of iron in its composition in combination with ascorbic acid.
Iron, in itself, is an integral part of the human body, its important functional unit. It is a part of hemoglobin, takes part in oxidative reactions in tissues. Ascorbic acid improves the quality and affects the rate of absorption by the body of iron.
The special form, the matrix in which the drug is released, provides a gradual and slow release of iron. The process is not in the stomach, but in the duodenum and jejunum, under the action of peristalsis. The process is characterized by a high degree of absorption and bioavailability. More than 90% of active iron binds to blood proteins. The half-life is about six hours.

Indications for use

The medicine is prescribed:
    with iron deficiency in the body;
    anemia (due to a lack of iron);
    as a preventive measure in pregnant and lactating women and blood donors.

Contraindications

    drug allergy;
    hemosiderosis and hemochromatosis;
    other types of anemia;
    thrombosis and thrombophlebitis;
    diabetes mellitus and fructose intolerance;
    stenosis of the intestine;
    urolithiasis and other serious kidney diseases;
    children (up to 12 years);
    the parallel intake of preparations containing iron, problems with the assimilation of iron in the body.
In inflammation and peptic ulcer of the digestive system, the agent is used only for the intended purpose and under the supervision of a physician.

Side effects

The most common side effects are:
    constipation, diarrhea, nausea and pain in the epigastric region;
    redness and itching on the skin, Quincke's edema is possible;
    hyperglycemia;
    taking the drug promotes the formation of stones and sand in the kidneys;
    thrombocytosis, erythrocytopenia, leukocytosis;
    possible deviations from the normal content and exchange of zinc and copper in the body;
    headache, weakness, palpitations, dizziness;
    blackening or darkening of feces.

Instructions for use Sorbifer Durules (Method and dosage)

According to the instructions on Sorbifer, the tablet is swallowed whole, without chewing and not dividing into pieces, washed down with water.
Usually, if the doctor did not prescribe otherwise, the daily dose is 2 tablets (not more than four), divided into two doses. The course of treatment can be 3-4 months.

How to take the drug during pregnancy?

For preventive purposes, appoint one tablet a day, during treatment - 2 tablets. Therapy continues until the level of iron in the body is restored.

Overdose

Increased fatigue, weakness, lower blood pressure, abdominal pain and vomiting with blood are signs of an overdose.
It should be as soon as possible to seek help from a doctor, make a lavage of the stomach, give a person milk and raw eggs, enter deferoxamine.

Interaction

Do not combine the drug with ciprofloxacin, norfloxacin, levofloxacin, ofloxacin and moxifloxacin.
It is not recommended to combine food additives with calcium and magnesium, captopril, clodronate, cimetidine, levodopa, zinc, desferoxamine, methyldopa, tetracycline, penicillinamine, thyroid hormones, pancreatin, ethanol and tocopherol with sorbifer. The gap between taking medication should be left for less than two hours.
The combination of the drug with ascorbic acid can lead to an overdose of iron.
The process of drug absorption deteriorates when combined with milk, eggs, tea, coffee, juices, bread, foods rich in plant fibers. Also, digestion is adversely affected by oral contraceptives and chloramphenicol.

Storage conditions

Inaccessible to children, the temperature does not exceed 25 degrees.
Shelf life - 3 years.

With alcohol

When the drug is combined with ethanol, the degree of absorption of iron is increased. Perhaps increased adverse reactions.

Sorbifer during pregnancy and lactation

Sorbifer during pregnancy is prescribed for anemia.
According to the instructions, at the initial stages of pregnancy (the first six months), one tablet of the drug is recommended once a day. Last trimester and breastfeeding - 1 tablet twice a day.
Treatment continues until the level of iron in the blood is normalized. According to the doctor's prescription, the medication can be taken up to 6 months.

Reviews about Sorbifer Durules

Reviews during pregnancy are good. Recovery of hemoglobin is rapid. Side effects, with the recommended dosage, are rare. Some women prefer to drink tablets with alcohol, which increases the effectiveness of the drug, despite the fact that drinking alcohol during pregnancy is highly undesirable.